Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
Get full text

Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…After the first dose, limited antigen availability in germinal centers (GCs) results in a response dominated by B cells that target immunodominant epitopes that are mutated in an Omicron-like variant. After the second dose, these memory cells expand and differentiate into plasma cells that secrete antibodies that are thus ineffective for such variants. …”
Get full text

One Plus One is More than Two: A Practical Combination of Power and Fault Analysis Attacks on PRESENT and PRESENT-Like Block Ciphers by Patranabis, Sikhar, Mukhopadhyay, Debdeep, Breier, Jakub, Bhasin, Shivam

“…Our attack sheds light on a hitherto unexplored vulnerability of PRESENT and PRESENT-like block ciphers that use bit-permutations instead of maximum distance separable (MDS) layers for diffusion.…”
Get full text
Get full text

Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth by Pollock, K, Cheeseman, H, McFarlane, L, Day, S, Tolazzi, M, Turner, H, Joypooranachandran, J, Shramko, K, Dispinseri, S, Mundsperger, P, Bontjer, I, Lemm, N-M, Coelho, S, Tanaka, M, Cole, T, Korber, B, Katinger, D, Ward, A, Scarlatti, G, Sanders, R, Sattentau, Q, Shattock, R

“…<p><strong>Background:</strong> We report findings from an experimental medicine study of rationally designed prefusion stabilised native-like HIV envelope glycoprotein (Env) immunogens, representative of global circulating strains, delivered by sequential intramuscular injection.…”

Failures in computer contracts in the Eastern part of the United States. by Chan Yeung, Seah May Ling, Tan Eng Teng

Get full text

“新游牧精神”为文化冲突的和解方案 ：从《陆犯焉识》探讨严歌苓的身份认同 = “New normadic spirit” as a solution to cultural identity conflict : an analysis of Yan Ge Ling’s cultural identity through her novel, Lu Fan Yan Shi by See, Seow Ling

“…The renown American Chinese author Yan Ge Ling migrated to the United States in the 1980s. …”
Get full text

‘Russian military censorship, like the Russian warship, can go f*** itself.’ An analysis of Russian independent media response to wartime media freedom restrictions by Raspopina, Aleksandra

Get full text

Search for single-production of vector-like quarks decaying into Wb in the fully hadronic final state in pp collisions at s = 13 TeV with the ATLAS detector by Aad, G, Aakvaag, E, Abbott, B, Abdelhameed, S, Abeling, K, Abicht, NJ, Abidi, SH, Aboelela, M, Aboulhorma, A, Abramowicz, H, Abreu, H, Abulaiti, Y, Acharya, BS, Ackermann, A, Adam Bourdarios, C, Adamczyk, L, Addepalli, SV, Addison, MJ, Adelman, J, Adiguzel, A, Adye, T, Affolder, AA, Afik, Y, Agaras, MN, Barr, AJ, Bortoletto, D, Bruckler, TL, Celli, F, Chen, M, Conroy, EI, Cooper-Sarkar, AM, Dingley, T, Draguet, MA, Eberwein, GH, Frost, JA, Gallas, EJ, Grabarczyk, RP, Gwenlan, C, Haslbeck, F, Hays, CP, Hodkinson, BH, Huffman, TB, Iizawa, T, Karava, K, Koch, SF, Li, Z, Moser, B, Nagai, K, Nedic, L, Nickerson, RB, Pacey, HA, Rossi, E, Ruggiero, A, Schopf, E, Shipsey, IPJ, Sultan, DMS, Viehhauser, GHA, Weidberg, AR, Yildirim, TP

“…A search for T and Y vector-like quarks produced in proton-proton collisions at a centre-of-mass energy of 13 TeV and decaying into Wb in the fully hadronic final state is presented. …”

Work / memories of work by Arkomanis, Ektoras

Subjects: “…700 The arts; fine & decorative arts…”
Get full text

The risk management of unemployment. by Chan, Han Eng., Ling, Julian., Sim, Rodney Boon Hian.

“…Her population is greying. Singapore is likely to undergo a lot of changes, be it the social environment or the economic environment. …”
Get full text

Hybrid mesoporous microbeads based on sheets-like sulfur-doped copper oxide embedded in calcium alginate-derived carbon for batch and columnar adsorption of cationic dye by Naggar, Ahmed H., Alshammari, Mutairah S., Seaf-Elnasr, Tarek A., Chong, Kwok Feng, Bakr, Zinab H., Alotaibi, N. F., Ali, Hazim M., El-Nasser, Karam S., Thabet, Mahmoud, Abd El-Monaem, Eman M., Goda, Adel E. S., Gomaa, Hassanien

Get full text
Get full text

Reserving interior void space for volume change accommodation : an example of cable-like MWNTs@SnO2@C composite for superior lithium and sodium storage by Zhao, Yi, Wei, Chao, Sun, Shengnan, Wang, Luyuan Paul, Xu, Zhichuan Jason

“…Reserving interior void space in the cable-like structure of multiwalled carbon nanotubes-in-SnO2-in-carbon layer (MWNTs@SnO2@C) is reported for the first time. …”
Get full text
Get full text

Elucidation of functional significance of plasmodium falciparum reticulocyte binding like protein homologues - RH1, RH2A AND RH4 during merozoite invasion. by Karthigayan Gunalan.

“…One major family of ligands involved in these interactions is the Reticulocyte binding like protein Homologues (RHs). Using highly specific monoclonal antibodies against PfRH1, RH2a and RH4, we have focused on the processing and erythrocyte binding properties of RHs that are important for host cell recognition. …”
Get full text

Stand-alone and combined effects of protein hydrolysate and humic-like substances derived from waste materials on the growth, physiology and mineral nutrition of tea nursery plants by Raguraj, Sriharan, Kasim, Susilawati, Sanali, Bellana Vithanage Roshika, Senarathne, Thakshala Thilini Kumari, Weerathunga, Saman Kumara, Damayanthi, Maha Makkalage Nalika, Wijesinghe, Senarath Pathiranalage Shyamali Kumari, Amali, Rathnasekara Kuruppu Arachchige, Madushani, Maha Gamage Kusala, Liyanage, Liyana Rallage Mahesh Chaminda

“…This study was designed to investigate the effects of individual and combined application of protein hydrolysate (PH) and humic-like substances (HLS) along with the reduction of fertilizer on the growth, physiological and biochemical parameters and mineral nutrition of tea nursery plants. …”

Efficient water disinfection against antibiotic-resistant bacteria by visible-light heterogeneous photo-Fenton-like process with atomically dispersed Cu on graphitic carbon nitride as the catalyst by Liu, Hang, Wang, Tianyi, Liu, Sixiao, Zhou, Xiaoyu, Zhang, Lei, Sun, Yi, Hu, Yongfeng, Sharouri, Mohsen, Zhang, Yu, Teng, Zhenyuan, Zhang, Xiuyun, Wang, Guoxiu, Wang, Chengyin

“…Photocatalytic heterogeneous Fenton and Fenton-like processes can offer efficient pathogen removal, with benefits in recycling, solid–liquid separation, and byproduct avoidance. …”
Get full text

Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine by Kumar, Kiven, Tan, Wen Siang, Arshad, Siti Suri, Ho, Kok Lian

“…Immunization of BALB/c mice with the virus-like particles (VLPs) self-assembled from the recombinant CP showed that, with AddaVax as an adjuvant, a significantly high level of humoral response was elicited. …”
Get full text

Structure and functions of a metallo-beta-lactamase- like hypothetical protein bleg1_2437 from alkali-tolerant soil bacterium Bacillus lehensis G1 by Tan, Soo Huei

“…In the present study, there are 1202 hypothetical proteins (HPs) have been discovered from newly sequenced genome of alkali-tolerant soil bacterium B. lehensis G1, HP Bleg1_2437 may likely be an MBL. Domain and sequence analysis of HP Bleg1_2437 using InterProScan and DELTA-BLAST revealed that this 23 kDa protein contains highly conserved metal-binding residues such as H54, H56, D58, H59, H131 and H191 that are similar with the those in subclass B3 of MBL that are involved in the coordination of two Zn2+ ions. …”
Get full text

A standardised fraction 1 (SF1) from clinacanthus nutans attenuates the stemness of cervical cancer stem-like cells via inhibition of notch1 signalling by Ismail, Faridah

Get full text

Perceived impact of shift from income tax to GST by Singapore residents by Eng, Celina Soo Hwi, Ling, Hue Miin, Kuah, Beng Hui

Get full text

A comparison study between open book and closed book examinations. by Heng, Cecilia Pei Pei., Lim, Kenneth Eng Seng., Ng, Ee Ling.

Get full text