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7841
Analysis of lava flow impacts for use in risk assessments
Published 2023“…Along with the 2018 Kīlauea assessment, I used this compiled dataset to assess relationships between lava flow thickness as a proxy for hazard intensity and damage severity, presenting the first empirically-derived and non-linear fragility functions for lava flow structure damage, for different structure types. The findings show a recent increase in recorded impact events, and that these events occur more frequently than previously thought, with almost three impact events, to population centres, per decade in the past 100 years. …”
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Thesis-Doctor of Philosophy -
7842
Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore
Published 2024“…To compare interventions, we used the synthetic control method to generate appropriate counterfactuals for the intervention towns using a weighted combination of 30 control towns between EW 1, 2014 and EW 26, 2022. Findings: Our study comprised an at-risk population of 607 872 individuals living in intervention sites and 3 894 544 individuals living in control sites. …”
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Journal Article -
7843
The development and application of fish scale waste for tissue engineering applications : waste-to-resource conversion of resource resilient materials
Published 2017“…Therefore in this thesis, fish scale-derived collagen (FSCol) and fish scale-derived HA (FSHA) were extracted from different fish species and the potential of the extracted products for various TE applications were explored. Findings from the studies demonstrated that Type I FSCol was successfully extracted using a modified acid solubilization extraction method with preserved structural quality (i.e. retention of triple helical structures) where snakehead scale-derived collagen (SHCol) exhibited significant higher (p < 0.05) thermal stability as compared to other species. …”
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Thesis -
7844
Biomolecular hydration in protein-protein interaction, protein stability and aggregation and lead optimization : computational studies
Published 2017“…Combining systematic data mining and quantification of these hydration sites using „JAL‟ a novel two water-bridge motif is identified that appears to be central to the nucleotide recognition by eIF4E. This is a novel finding and I believe will facilitate the design of specific inhibitors of eIF4E which is a therapeutic target in oncology. …”
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Thesis -
7845
New algorithms for hardware-efficient implementation of sign detection and magnitude comparison in residue number systems
Published 2017“…Specifically, the following new findings and results are reported in this thesis. …”
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Thesis -
7846
Cardiac-sympathetic dysfunction in hypertension
Published 2018“…Chapter seven also discussed the implications of the findings described, with an emphasis on the potential future avenues of research within the field of neurogenic hypertension.…”
Thesis -
7847
Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Published 2024“…We also calculated burden of stroke attributable to 23 risk factors and six risk clusters (air pollution, tobacco smoking, behavioural, dietary, environmental, and metabolic risks) at the global and regional levels (21 GBD regions and Socio-demographic Index [SDI] quintiles), using the standard GBD methodology. 95% uncertainty intervals (UIs) for each individual future estimate were derived from the 2·5th and 97·5th percentiles of distributions generated from propagating 500 draws through the multistage computational pipeline. <p><b>Findings</b></p> In 2021, stroke was the third most common GBD level 3 cause of death (7·3 million [95% UI 6·6–7·8] deaths; 10·7% [9·8–11·3] of all deaths) after ischaemic heart disease and COVID-19, and the fourth most common cause of DALYs (160·5 million [147·8–171·6] DALYs; 5·6% [5·0–6·1] of all DALYs). …”
Journal article -
7848
Epidemiology of endometriosis in women of Arab ancestry
Published 2021“…</p> <p>Conclusion</p> <p>This study provided novel findings of the clinical presentation and risk factors of endometriosis among Arab women from a combined hospital and population-based sites. …”
Thesis -
7849
Immunoprofiling of drug-resistant epilepsy with a focus on glutamic acid decarboxylase 65 antibodies
Published 2021“…Pain was reported as a seizure trigger in three patients, an unusual finding in epilepsy.</p> <p>Cytokine concentrations measured by a multiplex bead-based immunoassay combined with flow cytometry showed GAD65 autoantibody-positive DRE patient plasmas were enriched for IL1b, IL4, IL10, IL15 and TNFa, consistent with multifaceted immune system involvement. …”
Thesis -
7850
Effects of Edible bird's nest on quality of Arabian stallion semen and post-breeding induced endometritis in mares
Published 2022“…Glandular density and conception rate was also higher (P>0.05) in mares treated with H-EBN relative to LEBN and control. These findings depict the promising role of EBN in preserving chilled and frozen semen quality, and as an alternative reproductive medicine in selectively targeting mares susceptible to PBIE.…”
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Thesis -
7851
Retention and storage stability of vitamins A and C in extruded native and pregelatinized starches
Published 2015“…It can be concluded that in all the extruded starches, the stability during extrusion and upon storage was significantly higher for vitamin C than vitamin A. The findings provided information on the application of the fixed extrusion conditions for better retention of vitamin A or vitamin C in starches. …”
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Thesis -
7852
Neuroprotective effect of tocotrienol-rich fraction and a-tocopherol of vitamin E against glutamate toxicity in neuronal cells and astrocytes
Published 2015“…The flow cytometry morphological findings were validated by scanning electron microscopy analysis. …”
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Thesis -
7853
Factors associated with body weight status and internet addiction among malaysian university students in Penang: mixed method study before and during covid-19 pandemic
Published 2024“…They were also encouraged to share their perception of face-to-face personal interaction with family and friends, sports and other offline activities as compared to similar online activities. The findings of this study prove that there is a significant contribution of demographic and socio-economic factors to internet addiction among Malaysian university/college students in Penang. …”
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Thesis -
7854
From the microbial to the mechanical : environmental impacts on coral nitrogen cycling, microbial communities, and skeletal properties
Published 2021“…As Porites corals are likely to incur higher forces in the direction parallel to corallite growth, particularly from predation, anisotropy may provide the skeleton with a structural advantage. …”
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Thesis-Doctor of Philosophy -
7855
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2022“…We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings: Globally in 2019, 1·14 billion (95% uncertainty interval 1·13–1·16) individuals were current smokers, who consumed 7·41 trillion (7·11–7·74) cigarette-equivalents of tobacco in 2019. …”
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Journal Article -
7856
Evaluating conversational agents for mental health: scoping review of outcomes and outcome measurement instruments
Published 2023“…Descriptive and thematic analyses of the findings were performed. Results: We included 32 studies that targeted the promotion of mental well-being (17/32, 53%) and the treatment and monitoring of mental health symptoms (21/32, 66%). …”
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Journal Article -
7857
Doctor, Will You Pray for Me? : Medicine, Chaplains, and Healing the Whole Person /
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software, multimedia -
7858
Modelling familiarity : towards age-friendly exergame design
Published 2020“…Based on all the research findings, familiarity can contribute to age-friendly exergame design and older adults' game experience can be enhanced with the help of this research.…”
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Thesis-Doctor of Philosophy -
7859
Individual-fMRI-approaches reveal cerebellum and visual communities to be functionally connected in obsessive compulsive disorder
Published 2021“…While the main results were consistently observed with accounting for head motion and using another atlas, the key findings were not reproduced with GSR application. …”
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Journal Article -
7860
ESBL and AmpC β-lactamase encoding genes in E. coli from pig and pig farm workers in Vietnam and their association with mobile genetic elements
Published 2021“…Overall, despite evidence of transferability of plasmids in the analyzed strains, our findings do not support that ESBL-producing E. coli from pigs or their ESBL/AmpC encoding plasmids are commonly spread to workers in close contact with the animals.…”
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Journal Article