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Ion pairs for transdermal and dermal drug delivery: a review
Published 2021“…This review attempts to show the various ways in which ion pairs have been used in drug delivery via the skin. It also endeavours to extract and consolidate common approaches in order to inform future formulations for topical and transdermal delivery.…”
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Preparation, characterization and dermal delivery of methadone
Published 2019“…The first stage of the work was the preparation of methadone free base as this form of the drug is expected to permeate the skin to a greater extent than the hydrochloride salt. …”
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Topical delivery of Niacinamide: influence of binary and ternary solvent systems
Published 2019“…Previously, we reported a comparative study of NIA permeation from neat solvents using the Skin Parallel Artificial Membrane Permeability Assay (PAMPA) and mammalian skin. …”
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Characterization and topical delivery of phenylethyl resorcinol
Published 2019“…The permeation through porcine skin at 24 h ranged from 4 to 13 μg/cm2, while the corresponding amounts of PR delivered through human skin were 2 to 10 μg/cm2. …”
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Investigation of binary and ternary solvent systems for dermal delivery of methadone
Published 2020“…Nine formulations were subsequently examined in human skin. A good correlation (r2 = 0.80) for methadone permeation was obtained between porcine ear skin and human skin data. …”
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Dermal delivery of amitriptyline for topical analgesia
Published 2021“…Volatile formulations comprising of isopropyl alcohol (IPA) and isopropyl myristate (IPM) or propylene glycol (PG) were evaluated in porcine skin under finite dose conditions. Compared with neat IPM, the IPM:IPA vehicles promoted 8-fold and 5-fold increases in the amount of amitriptyline that permeated at 24 h. …”
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Overview of Jute Fibre as Thermoplastic Matrix Polymer Reinforcement
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3D-printed Franz type diffusion cells
Published 2019“…Franz cells are routinely used to measure in vitro skin permeation of actives and must be inert to the permeant under study. …”
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Antivirals for broader coverage against human coronaviruses
Published 2024“…Spike is also not applicable for targeting other HCoVs as these are not well-conserved sequences among human CoVs. …”
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Reflectance spectroscopy system for real time and non-invasive detection of transcutaneous bilirubin level
Published 2018“…In addition, a lower bilirubin was observed for individuals with dark skin compared to fair skin, and a higher bilirubin level in male compared to their female counterparts. …”
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Siam weed based hydrogel hybrid for tissue engineering
Published 2020“…Tissue engineered skin grafts have been considered as an auxiliary for replacement of damaged skin due to burns and injury. …”
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Acne Severity Classification on Mobile Devices using Lighweight Deep Learning Approach
Published 2024“…Acne is a prevalent skin condition affecting millions of people globally, impacting not just physical health but also mental well-being. …”
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The role of excipients in promoting topical and transdermal delivery: current limitations and future perspectives
Published 2022“…The emphasis here is on studies focused on passive skin transport, because of clinical limitations associated with disrupting the skin barrier by physical methods. …”
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Topical delivery of niacinamide: influence of neat solvents
Published 2020“…The aim of the present work was therefore to investigate skin delivery of NIA from single solvent systems in porcine skin under finite dose conditions. …”
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