DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11 by Loh Jia Tong, Teo, Joey Kay Hui, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Andiappan, Anand Kumar, Lim, Hong-Hwa, Lam, Kong-Peng

“…Knocking out Dok3 enhanced the production of the cytokine IFN-γ by T cells, which conferred protection against experimental atopic dermatitis-like skin inflammation in mice. The expression of DOK3 was increased in T cells isolated from patients with atopic dermatitis and inversely correlated with IFNG expression. …”
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Engineering nano-nodular pattern on the substrate surface by tuning phase inversion to construct ultrapermselective ion-separation nanofiltration membrane by Zhao, Yali, Li, Can, Liao, Yuan, Yin, Yurong, Wang, Rong, Chen, Dongliang

“…Consequently, a PA membrane with nano-nodular pattern, thin skin layer, narrow pore size distribution and negative charge was formed. …”
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Computation fluid dynamics on drag reduction II by Zang, Bin

“…Lastly, the grid size and RANS models are subjected to further verification to ensure the observations and calculations are indeed trustworthy and relatively accurate by studying skin friction coefficient and comparing to empirical formula; also by simulating more complex dimpled flow with different Reynolds number regimes. …”
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A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…Many across-domain pairs exhibited substantial shared genetics (e.g., iron deficiency anaemia and peripheral arterial disease: genetic correlation 𝑅𝑔 = 0.45 [95% Confidence Intervals 0.27:0.64]). 33 pairs displayed negative genetic correlations, such as skin cancer and rheumatoid arthritis (𝑅𝑔 = −0.14 [−0.21:−0.06]), due to potential adverse drug effects. …”

Association between feel-like temperatures and injury risk during international outdoor athletic championships: a prospective cohort study on 29 579 athlete starts during 10 champi... by Edouard, P, Dandrieux, P-E, Klöwer, MK, Junge, A, Racinais, S, Branco, P, Hollander, K, Navarro, L

“…We performed Poisson regressions with incidence rates (number of injuries per 1000 athlete starts) as outcomes and UTCI as a predictive variable adjusted for sex, for all and time-loss injuries, for different injured tissue types (ie, muscle, tendon, ligament, articular, bone and skin) and specific discipline (ie, sprints, hurdles, jumps, throws, middle distance, long distance, marathon and race walking).…”

Fractional exhaled nitric oxide (FeNO) among school children in Java and Sumatra, Indonesia: associations with respiratory symptoms, house dust mite sensitization and the home envi... by Norbäck, Dan, Hashim, Jamal Hisham, Hashim, Zailina, Jalaludin, Juliana, Ismail, Rohaida, Wieslander, Gunilla, Wispriyono, Bambang, Sary, Lolita, Pratama, Satria, Sari, Meliana, Sisinta, Tiaraima, Putra, Hondli, Perdana, Agung Aji, Muhani, Nova, Lestari, Sri Maria Puji, Wulandari, Ririn, Nurmala, Eliza Eka

“…Methods: Data on health and home were collected by a face-to face interview before measuring FeNO and performing skin prick test against common allergens. Exploratory linear mixed and logistic regression models were employed. …”
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Quantifying the internal and external drivers of Southeast Asian rainfall extremes on decadal timescales by Wang, Shouyi, Ummenhofer, Caroline C., Murty, Sujata A., Nguyen, Hung T. T., Buckley, Brendan M.

“…Volcanic aerosols, the most effective radiative forcing during the last millennium, contributed to both the Ming Dynasty Drought (1637–1643) and the Strange Parallels Drought (1756–1768). …”
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Environmental and social factors influencing the spatiotemporal variation of archaeological sites during the historical period in the Heihe River basin, northwest China by Shi, Zhilin, Chen, Tingting, Storozum, Michael J., Liu, Fengwen

“…In the Western Xia-Yuan period (AD 1038–1368), people mainly settled in the lower reaches of the Heihe River basin and only returned to the middle reaches of the Heihe River basin during the Ming and Qing dynasties (AD 1368–1912). Although climate change and the local environment affected human activities in Heihe River basin, geopolitical events, such as forced mass migrations, are more responsible for influencing the distribution of archaeological sites over the past 2000 years.…”
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An in-depth study of software library upgrade dependency issues by Teo, Dave Hwa Tao

“…This final year project will be an extension of a previous study done by my senior, Nicholas Yeo Ming Jie (Project ID: SCSE21-0215), which had proposed a method to detect these vulnerabilities using Concrete Syntax Tree (CST) generated by parsing projects using LibCST. …”
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Ternary blend organic bulk heterojunction photovoltaics based on incorporation of low bandgap materials by Ling, Jin

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Friction stir processing of 3D-printed metal composites by Lim, Dalton Jun Jie

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A generalized solution to verify authorship and detect style change in multi-authored documents by Leekha, Rohan, Vandam, Courtland

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Dual-phase microporous polymer nanofilms by interfacial polymerization for ultrafast molecular separation by Lee, Tae Hoon, Balcik, Marcel, Wu, Wan-Ni, Pinnau, Ingo, Smith, Zachary P

“…Fine-tuning microporosity in polymers with a scalable method has great potential for energy-efficient molecular separations. …”
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A multiplicative Nakagami speckle reduction algorithm for ultrasound images by Yu, Chengpu, Zheng, Cishen, Xie, Lihua

“…A 2D total variation regularized Nakagami speckle reduction algorithm is derived based on the maximum a posteriori estimation framework, which performs well in restoring piecewise-smooth reflectivity and preserving fine details of the image. The proposed algorithm is verified by a series of computer-simulated and real ultrasound image data. …”
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A communal furniture informed by the deprivation of Mauritian beach by Fok Kow, Fok-Chi-Seng

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Life and dyeing : floral escapes by Teng, Yu Qing

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Beyond the beautiful garden city by Koh, Kevin Jing Sen

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A 9-bit, 1.08ps resolution two-step time-to-digital converter in 65 nm CMOS for time-mode ADC by Kong, Junjie, Henzler, Stephan, Schmitt-Landsiedel, Doris, Siek, Liter

“…The proposed TDC uses body-biasing in the fine TDC to obtain the resolution of the entire TDC, which is simulated to be 1.08 ps. …”
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Of dreams and reality : chance on graphic design. by Chu, Tracey Shao Han.

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Hierarchical document representation for summarization by Tey, Rui Jie

“…HIWESTSUM is very light in weight with parameter size over 10 times smaller than current existing models that fine-tune BERT for summarization. Moreover, the proposed model is faster than SOTA models with shorter training and inference time. …”
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