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6361
Proteomic network of antibiotic-induced outer membrane vesicles released by extensively drug-resistant Elizabethkingia anophelis
Published 2023“…Furthermore, this is the first study to discuss the protein-protein interaction network of the OMVs released by E. anophelis, especially under antibiotic stress. Our findings provide important insights into clinical antibiotic stewardship.…”
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Journal Article -
6362
Foot care behaviours and associated factors among patients with type 2 diabetes: a cross-sectional study
Published 2024“…Additionally, more FC knowledge increased the likelihood by 20% (OR=1.21; 95% CI=1.10–1.33), and higher diabetes-related stress increased it by 1.03 times (OR=1.03; 95% CI=1.02–1.05). Conclusions: Our findings underscore the interplay of various factors influencing FC behaviours among individuals with diabetes and call for targeted interventions and tailored strategies to improve FC practices in this vulnerable population.…”
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Journal Article -
6363
Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration
Published 2018“…Concomitant with TDP-43 aggregation and proteolysis after prolonged arsenite exposure, GADD34-bound CK1ϵ catalyzed TDP-43 phosphorylations at serines 409/410, which were diminished or absent in GADD34−/− cells. Our findings highlight that the phosphatase regulator, GADD34, also functions as a kinase scaffold in response to chronic oxidative stress and recruits CK1ϵ and oxidized TDP-43 to facilitate its phosphorylation, as seen in TDP-43 proteinopathies.…”
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Journal Article -
6364
The capabilities of Multiclass Support Vector Machine (MSVM) training algorithms in grading agarwood essential oil
Published 2024“…The agarwood essential was graded into five grades (low, medium low, upper low, medium high, and high) and six grades (low, medium low, upper low, medium high, high, and upper high). The findings of this paper show the confusion matrix for five grades and six grades have no mismatch between actual and predicted data. …”
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Article -
6365
Experimental and Computational Advancements in Peptidomimetic Ligand Discovery
Published 2024“…At the same time, discovery tools for finding peptides that modify PPIs have evolved, including advances in affinity selection techniques and combinatorial chemistry. …”
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Thesis -
6366
Revealing Structural and Spin-state Dependent Reactivity of Single Atom Catalysts (SACs) with Systematically Improvable Computational Tools
Published 2024“…The ML models demonstrate superior accuracy in predicting reaction energetics compared to traditional scaling relationships. The findings validate codoping as a powerful strategy for tuning the properties of SACs to achieve enhanced ORR performance. …”
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Thesis -
6367
Shifting Paradigms: Data-Centric Approach for Marine Statics Correction using Symmetric Autoencoding
Published 2024“…This notable precision improvement using SymAE highlights how a streamlined data-centric paradigm outperforms the traditional model-centric paradigm of marine statics correction. This finding is pivotal as it is the foundation that lays the groundwork and opens the path towards the real-world deployment of SymAE for statics correction in challenging deepwater environments.…”
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Thesis -
6368
Design, fabrication and characterization of organic-inorganic hybrid solar cells
Published 2020“…Moreover, the literature review provides the information about different types of lead-free solar cells and their advantages and their drawbacks. The achieved findings in this thesis include the following: (1) Six NDI-based molecules have been designed and synthesized as electron transporting layers in inverted perovskite solar cells; (2) Two pyrene-based molecules were designed and synthesized as electron transporting layers; (3) The effect of sulfur position in pyrene-based molecules was investigated (4) Three N-type conjugated polymers were explored as electron transporting layer (5) The effect of embedded sp2-nitrogen in donor and acceptors of conjugated polymer was explored and (6) Tellurium tetraiodide was explored as a promising light absorber in solar cells. …”
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Thesis-Doctor of Philosophy -
6369
Creative ageing in Singapore : a population study on participatory arts engagement and wellbeing among adults aged 50 and above
Published 2020“…Respondents expressed that their greatest interest lies within the genre of culture and heritage arts, with a strong preference to engage in arts activities within the community, and to attend such activities with their family or friends. Findings from propensity score matching with t-test analyses revealed that respondents who passively engaged in the arts experienced better quality of life t(728) = 3.35, p = .0008, d = .25, self-perceived health t(728) = 2.21, p = .028, d = 0.16, and sense of belonging t(728) = 2.17, p = .028, d = 0.16, as compared to those who did not. …”
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Thesis-Master by Research -
6370
Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination
Published 2020“…Similarly within the scaffolds, miR-219/miR-338 samples contained significantly more myelin basic protein (MBP) signals (p < 0.01) and higher myelination index (p < 0.05) than Neg miR samples. These findings highlight the potential of this platform to promote remyelination within the CNS.…”
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Journal Article -
6371
TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR4 Interacts with WRINKLED1 to mediate seed oil biosynthesis
Published 2020“…In addition, TCP4 repressed the AtWRI1-mediated transactivation of the promoters of fatty acid biosynthetic genes. Collectively, our findings suggest that TCP4 represses fatty acid biosynthetic gene expression through interaction with AtWRI1, leading to a reduction of AtWRI1-mediated seed oil accumulation.…”
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Journal Article -
6372
Multi-path region mining for weakly supervised 3D semantic segmentation on point clouds
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Conference Paper -
6373
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6374
Three essays on behavioral and experimental economics
Published 2021“…We explain this difference on the basis of the Singaporean senders’ beliefs about trustworthiness: they believed that people with a Mainland Chinese accent would return more money to them than their in-group Singaporean counterparts. To bolster our findings, we confirmed in a separate experiment that the difference in response to the accents was not due to the speed of speech or vocal pitch. …”
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Thesis-Doctor of Philosophy -
6375
Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells
Published 2021“…Given the high prevalence of CMV worldwide, our findings point to a significant global health issue. …”
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Journal Article -
6376
Prediction of stable perovskite quantum dots (QDs) using machine learning (ML) algorithms
Published 2022“…Falling back to literature of known understanding of the photoluminescence property, suggested that the nanocrystal’s surface ligands interface has a substantial impact on optical properties. Hence finding a method to incorporate the string data type of synthesis methods and passivation agents to machine learning models who typically prefer numerical data types could improve the prediction abilities.…”
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Final Year Project (FYP) -
6377
Understanding lay conceptions of workplace criers: a prototype analysis
Published 2022“…Moreover, they were quicker to disconfirm peripheral features as typical of workplace criers, compared to central features. These findings corroborated the prototype structure by demonstrating its impact on implicit cognition. …”
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Thesis-Doctor of Philosophy -
6378
Direct and indirect effects of fire on microbial communities in a pyrodiverse dry-sclerophyll forest
Published 2022“…Pathogenic fungi also increased in recently burnt forests that had a low fire frequency, mediated by a decline in litter carbon and an increase in soil pH in these sites. Synthesis. Our findings indicate that predicted increases in the frequency of fire may select for specific microbial communities directly and indirectly through ecological interactions, which may have functional implications for plants (increase in pathogens, decrease in symbionts), decomposition rates (declines in Actinobacteriota and Acidobacteriota) and carbon storage (decrease in ectomycorrhizal fungi). …”
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Journal Article -
6379
关中方言的体貌系统 = The aspect of the Guanzhong dialect
Published 2022“…It found that the Guanzhong dialect has a more comprehensive aspectual system and more markers for aspect if compared with Standard Mandarin. The data and findings of this study will serve as important references for the studies of aspect in both Chinese dialects and languages in general.…”
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Thesis-Master by Research -
6380
Improved mobility and photovoltaic performance of two-dimensional Ruddlesden−Popper (ThMA)₂(MA)₂M₃I₁₀ perovskites applied in perovskite solar cells
Published 2023“…Nevertheless, (ThMA)2(MA)2Cu3I10 was predicted to have the highest PCE of 22.97%, featuring itself as a potential photo–absorber candidate for photovoltaic applications. The findings reported herein not only achieve our goal in designing highly efficient and environmentally-friendly 2DRP perovskites, but also shed light on new strategies for advancing their applications in optoelectronic.…”
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Journal Article