Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank by Lassen, FH, Venkatesh, SS, Baya, N, Hill, B, Zhou, W, Bloemendal, A, Neale, BM, Kessler, BM, Whiffin, N, Lindgren, CM, Palmer, DS

“…We phased rare variants (MAF ∼0.001%) in the UK Biobank (UKBB) exome-sequencing data to characterize recessive effects in 175,587 individuals across 311 common diseases. A total of 6.5% of individuals carry putatively damaging CH variants, 90% of which are only identifiable upon phasing rare variants (MAF < 0.38%). …”

Tailored dose baclofen in patients with alcoholic liver disease: A case series with 2-year follow-up of hospitalisation by Heydtmann, M, Macdonald, B, Lewsey, J, Masson, N, Cunningham, L, Irnazarow, A, Nardone, A, Cosgrave, J, Chick, J

“…</p> <p><strong>Methods:</strong> Fifty-three hospitalised patients with alcoholic liver disease started tailored dose baclofen (median: 5.05 months, median highest dose before tapering down: 60 mg). …”

Deubiquitinases in muscle physiology and disorders by Olie, CS, O'Brien, DP, Jones, HBL, Liang, Z, Damianou, A, Sur-Erdem, I, Pinto-Fernández, A, Raz, V, Kessler, BM

“…Several mutations in DUB encoding genes are linked to human NMDs, such as ATXN3, OTUD7A, UCHL1 and USP14, whilst other NMDs are associated with dysregulation of DUB expression. USP5, USP9X and USP14 are implicated in synaptic transmission and remodeling at the neuromuscular junction. …”

Establishing the association between traditional tobacco, e-cigarette and dual use and mental health problems among high school students: results from a 2022 behavioral surveillanc... by Thepthien, BO, Tinn, CS, Sharma, R

“…A secondary analysis was conducted using data from 2022 Bangkok Behavioral Surveillance Survey (BBSS) (6,000 invited, 5,740 completed). Among the respondents, approximately, 14.1% used EC only, 11.0% used CC only, and 7.9% used both in the past year. …”

Prevalence and risk factors for suicide attempts in prison by Favril, L, Shaw, J, Fazel, S

“…A total of 20 studies comprising 19,882 individuals (6.5% women) in 20 countries were eligible for inclusion. …”

Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics by Perochon, T, Krsnik, Z, Massimo, M, Ruchiy, Y, Romero, AL, Mohammadi, E, Li, X, Long, KR, Parkkinen, L, Blomgren, K, Lagache, T, Menassa, DA, Holcman, D

“…Additionally, we uncover an association between microglia and blood vessels in fetal brains exposed to maternal SARS-CoV-2. These findings offer insights into whether various microglial phenotypes form networks in the developing brain to occupy space, and in conditions involving haemorrhages, whether microglia respond to, or influence changes in blood vessel integrity. …”

A review of high-speed rotating HP turbine heat transfer and cooling studies over the last decade in the Oxford Turbine Research Facility by Falsetti, C, Beard, PF, Cardwell, DN, Chana, KS

“…Major upgrades include: (i) a combustor simulator able to produce engine radial and circumferential temperature profiles and inlet swirl simultaneously to study combustor-turbine interaction, (ii) fully film-cooled HP turbine designs and 1.5 stage configurations with a low-turning strut, (iii) novel rotor casing effusion cooling concepts, (iv) an advanced in-shaft data acquisition electronics system. …”

Additive manufacturing of tantalum scaffolds: processing, microstructure and process-induced defects by Aliyu, AAA, Poungsiri, K, Shinjo, J, Panwisawas, C, Reed, RC, Puncreobutr, C, Tumkanon, K, Kuimalee, S, Lohwongwatana, B

“…The presence of oxygen resulted in the formation of some oxide phases such as Ta2O5 and Ta2O3. Numerous process-induced defects, including solidification-induced micropores, pores-induced and solidification-induced microcracks were identified. …”

Strain‐modulated ferromagnetism at an intrinsic van der Waals heterojunction by Fujita, R, Gurung, G, Mawass, M, Smekhova, A, Kronast, F, Toh, AK, Soumyanarayanan, A, Ho, P, Singh, A, Heppell, E, Backes, D, Maccherozzi, F, Watanabe, K, Taniguchi, T, Mayoh, DA, Balakrishnan, G, van der Laan, G, Hesjedal, T

“…In this work, the piezoelectricity of the exfoliated van der Waals piezoelectric α-In2Se3 is utilized to modify the magnetic properties of exfoliated Fe3GeTe2, a van der Waals ferromagnet, resulting in increased domain wall density, reductions in the transition temperature ranging from 5 to 20 K, and an increase in the magnetic coercivity. …”

Board characteristics and financial performance: evidence from Bursa Malaysia Financial Times Stock Exchange (FTSE) top 100 index firms by Nur Hafizah Abdul Puhat, Suhaily Hasnan, Khairul Ayuni Mohd Kharuddin, Hafizah Marzuki, Mazurina Mohd Ali

“…The small percentage of politically-connected directors (19%) and military-experienced directors (5%) reported in this study can be viewed favourably in line with the recent MCCG 2021 recommendation that the appointment of the directors should be apolitical or politically neutral without having any executive powers in politics. …”
Get full text

Potential utilization of phenolic acid compounds as anti-inflammatory agents through TNF-α Convertase inhibition mechanisms: a network pharmacology, docking, and molecular dynamics... by Ekowati, Juni, Tejo, Bimo A., Maulana, Saipul, Kusuma, Wisnu Ananta, Fatriani, Rizka, Ramadhanti, Nabila Sekar, Norhayati, Novianty, Kholis Amalia, Sulistyowaty, Melanny Ika, Zubair, Muhammad Sulaiman, Yamauchi, Takayasu, Hamid, Iwan Sahrial

“…Among tested compounds, chlorogenic acid (−6.90 kcal/mol), rosmarinic acid (−6.82 kcal/mol), and ellagic acid (−5.46 kcal/mol) exhibited the strongest binding affinity toward TNF-α convertase. …”

oltammetric studies on microcrystalline C60 adhered to an electrode surface by solvent casting and mechanical transfer methods by Tan, W., Lim, E., Bond, A.

“…These data enable reversible potentials of -816 and -1168 mV vs. Ag/Ag+ to be obtained in acetonitrile (0.1 M NBu4PF6) respectively for the processes: C60(solid) + NBu4+(solution) + e- ⇌ NBu4 C60(solid) and NBu4C60(solid) + NBu4+(solution)+ e- ⇌ (NBu4)2C60(solid). …”

Effects of variety and stage of fruit ripeness on the physicochemical and sensory characteristics of deep‐fat‐fried banana chips by Ammawath, Wanna, Che Man, Yaakob, Yusof, Salmah, A Rahman, Russly

“…The fruits were peeled, sliced to a thickness of 2 mm and deep-fat fried in refined, bleached and deodorised (RBD) palm olein at 180±5°C for 3 min. The quality parameters determined for fresh bananas were total soluble solids, pH, acidity, carbohydrate, sugar content, fat, protein, moisture content, ash, fibre, colour and fruit firmness. …”
Get full text

Urinary excretion of duodenal purine derivatives in Kedah-Kelantan cattle by Pimpa, O, Liang, J.B, Jelan, Z.A, Abdullah, N

“…Three male Kedah-Kelantan (KK) cattle each fitted with a ruminal and a T-shaped duodenal cannulae, with an initial body weight of 178.3 ± 5.78 kg were used to study the recovery rate of urinary purine derivatives (PD) after duodenal infusion of incremental amounts of purine bases (PB). …”
Get full text

Effect of Dactylaria higginsii on interference of Cyperus rotundus with L. esculentum by Kadir, J.B., Charudattan, R., Stall, W.M., Bewick, T.A.

“…Cyperus rotundus plants were inoculated by spraying with a spore suspension of D. higginsii containing 0.5% Metamucil as a carrier. The treatments were Metamucil only, 104 conidia ml-1 + Metamucil, or 106 conidia ml-1 + Metamucil. …”

Effect of B2O3 on the physical and mechanical properties of calcium fluoroaluminosilicate glass system by Mohammed Efa, Abdelkader, Matori, Khamirul Amin, Mohd Zaid, Mohd Hafiz, Che Abdullah, Che Azurahanim, Zainuddin, Norhazlin, Mayzan, Mohd Zul Hilmi, Kamis, Shahira Liza

“…. © The Author(s), under exclusive licence to Springer Nature B.V. 2024.…”

Agaro-oligosaccharides enhanced the Monilinia fructicola resistance of peach fruit by regulating antioxidative and phenylpropanoid metabolism by Li, Qian, Wei, Yingying, Chen, Yi, Jiang, Shu, Ye, Jianfen, Xu, Feng, Lou, Yongjiang, Ding, Phebe, Ouaziz, Meriem, Shao, Xingfeng

“…These findings demonstrated that agaro-oligosaccharides induced the disease resistance of peach fruit, which was attributed to the activation of antioxidative and phenylpropanoid metabolism. © 2024 Elsevier B.V.…”
Get full text

Isolation, characterization and identification of plant growth-promoting rhizobacteria from the rhizosphere of Acacia mangium at sandy BRIS soil by Mustapha, Zakiah, Othman, Radziah, Nik Muhammad Nasir, Nik Nurnaeimah, Zawawi, Dhiya Dalila

“…A total of 24 pure colonies were isolated and only 8 colonies were selected for further evaluation of the growth rate in 5% organic molasses medium supplemented with 2% KNO3. …”
Get full text

Human health risk, potentials of biomonitoring and phytoremediation of copper using Amaranthus viridis by Al-Mutairi, K.A., Yap, C.K.

“…From a biomonitoring point of view, the Cu concentrations in the leaves, stems, and roots of A. viridis ranged from 10.8 to 21.9 µg/g dw (1.30-2.63 µg/g ww), 5.96 to 14.60 µg/g dw (0.36-0.88 µg/g ww), and 9.17 to 30.68 µg/g dw (1.01-3.37 µg/g ww), respectively. …”
Get full text

Improved bacterial foraging optimization algorithm with machine learning-driven short-term electricity load forecasting: a case study in peninsular Malaysia by Zaini, Farah Anishah, Sulaima, Mohamad Fani, Wan Abdul Razak, Intan Azmira, Othman, Mohammad Lutfi, Mokhlis, Hazlie

“…The comparative analysis demonstrates the model, achieving the highest determination coefficient (R2) of 0.9880 and significantly reducing the average MAPE value by 28.36%, 27.72%, and 5.47% compared to the deep neural network (DNN), LSSVM, and LSSVM-BFOA, respectively. …”
Get full text