SARS-CoV-2 evolution during treatment of chronic infection by Kemp, SA, Collier, DA, Datir, RP, Ferreira, IATM, Gayed, S, Jahun, A, Hosmillo, M, Rees-Spear, C, Mlcochova, P, Lumb, IU, Roberts, DJ, Chandra, A, Temperton, N, Sharrocks, K, Blane, E, Modis, Y, Leigh, KE, Briggs, JAG, van Gils, MJ, Smith, KGC, Bradley, JR, Smith, C, Doffinger, R, Ceron-Gutierrez, L, Barcenas-Morales, G, Pollock, DD, Goldstein, RA, Smielewska, A, Skittrall, JP, Gouliouris, T, Goodfellow, IG, Gkrania-Klotsas, E, Illingworth, CJR, McCoy, LE, Gupta, RK

“…The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for virus infection through the engagement of the human ACE2 protein1 and is a major antibody target. …”

A systems biology approach to define SARS-CoV-2 correlates of protection in non-human primates by Brady, C

“…The relationship between spike antibody isotype, IgG subclass, glycosylation and functional responses, and the relationship between these properties and protection, was explored. …”

Timekeeper by Ng, Yang Meng

“…Timekeeper is a short film about the chanced meeting of Hock and Anna. Hock, a retired watchmaker, enjoys collecting obsolete objects because he treasures the value in them. …”
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Driving mechanism development for autonomous hospital bed by Tan, Jia Liang

“…Demand is foreseen to spike and a range of healthcare services that range from acute to community care is necessary for a holistic healthcare system. …”
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Existence and Analysis of a Rotating Stall Inception Continuum & Development of Concept Questions in Fluid Dynamics by Cherry, Maranda F.

“…The divergence of stall inception from two-dimensionality is suggested as a distinguishing feature of spike type stall inception compared to modal type stall inception. …”
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Dealing with confounders in omics analysis by Goh, Wilson Wen Bin, Wong, Limsoon

“…The Anna Karenina effect is a manifestation of the theory-practice gap that exists when theoretical statistics are applied on real-world data. …”
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Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics by Roney, Miah, Huq, AKM Moyeenul, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…The most attractive antiviral targets of SARS-CoV-2 are the spike protein and main protease (Mpro). In this work, sixteen phenolic acids of Azadirachta indica were docked into the active site of the spike protein and Mpro. …”
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Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
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Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells by Carlevaro-Fita, Joana, Rahim, Anisa, Guigó, Roderic, Johnson, Rory, Vardy, Leah Karen Anne

“…Here we make a global, absolute estimate of the cytoplasmic and ribosome-associated population of stringently filtered lncRNAs in a human cell line using polysome profiling coupled to spike-in normalized microarray analysis. …”
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B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination by Kotagiri, P, Mescia, F, Rae, WM, Bergamaschi, L, Tuong, ZK, Turner, L, Hunter, K, Gerber, PP, Hosmillo, M, Hess, C, Clatworthy, MR, Goodfellow, IG, Matheson, NJ, McKinney, EF, Wills, MR, Gupta, RK, Bradley, JR, Bashford-Rogers, RJM, Lyons, PA, Smith, KGC

“…Infection generates a broad distribution of SARS-CoV-2-specific clones predicted to target the spike protein, while a more focused response after vaccination mainly targets the spike's receptor-binding domain. …”

Improved margin multi-class classification using dendritic neurons with morphological learning by Hussain, Shaista, Liu, Shih-Chii, Basu, Arindam

“…We present an architecture of a spike based multiclass classifier using neurons with non-linear dendrites and sparse synaptic connectivity where each synapse takes a binary value. …”
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Family factors and adolescent depression by Ho, Swee Yin.

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Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…The results showed a high prevalence of pre-existing immunity against seasonal coronaviruses when measuring IgG concentration of antibodies against spike protein but did not confer protection against SARS-CoV-2.…”

Numerical modelling of detonation reaction zone of nitromethane by EXPLO5 code and wood and kirkwood theory by Štimac, Barbara, Chan, Serene Hay Yee, Kunzel, Martin, Muhamed Suceska

“…The measured particle velocity profile of NM shows the existence of a sharp spike followed by a rapid drop over the first 5-10 ns (fast reaction). …”
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The Rise and Fall of the Ideal City by Scarso, Jacek Ludwig

“…Curated by Jacek Ludwig Scarso with Luisa Bravo and Anna Marazuela Kim. The Renaissance concept of the Ideal City is here a provocation to critically explore the ideological connotations of the urban context and the need for social change, locally and globally. …”
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Telephone conversation openings across languages, cultures and settings by Marquez Reiter, R., Kang, Luke Kwong Kapathy

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Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Chapter 4 focuses on the site-specific glycosylation occupancy, and N- and O-glycan structures attached to virion derived SARS-CoV-2 spike glycoproteins. This glycan signature was compared to a stabilised prefusion trimeric spike, to a monomeric subunit of spike (S1) and to an antigen of a non-stabilised vaccine candidate, revealing subunit shedding of the S1 glycoprotein for the vaccine candidate. …”

Comparative effects of domain-specific human monoclonal antibodies against LGI1 on neuronal excitability by Sell, J, Rahmati, V, Kempfer, M, Irani, SR, Ritzau-Jost, A, Hallermann, S, Geis, C

“…However, only the LRR-specific mAbs increased the number of action potential firing together with enhanced initial instantaneous frequency and promoted spike-frequency adaptation, which were less pronounced after the EPTP mAb. …”

Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations by Bi, Jialin, Wee, JunJie, Liu, Xiang, Qu, Cunquan, Wang, Guanghui, Xia, Kelin

“…Biologically, protein-protein interactions between SARS-CoV-2 surface spike (S) protein and human ACE2 protein are the key mechanism behind the COVID-19 disease. …”
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An exploratory study on Yingchou : Components of Yingchou for females in the chinese culture and their attitudes towards it. by Lin, Shi Yin.

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