Functional characterisation guides classification of novel BAP1 germline variants by Hong, Jing Han, Chong, Siao Ting, Lee, Po-Hsien, Tan, Jing, Heng, Hong Lee, Nur Diana Ishak, Chan, Sock Hoai, Teh, Bin Tean, Ngeow, Joanne

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The influence of soil age on ecosystem structure and function across biomes by Delgado-Baquerizo, Manuel, Reich, Peter B., Bardgett, Richard D., Eldridge, David J., Lambers, Hans, Wardle, David A., Reed, Sasha C., Plaza, César, Png, Kenny Guochen, Neuhauser, Sigrid, Berhe, Asmeret Asefaw, Hart, Stephen C., Hu, Hang-Wei, He, Ji-Zheng, Bastida, Felipe, Abades, Sebastián, Alfaro, Fernando D., Cutler, Nick A., Gallardo, Antonio, García-Velázquez, Laura, Hayes, Patrick E., Hseu, Zeng-Yei, Pérez, Cecilia A., Santos, Fernanda, Siebe, Christina, Trivedi, Pankaj, Sullivan, Benjamin W., Weber-Grullon, Luis, Williams, Mark A., Fierer, Noah

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A promising deep learning-assistive algorithm for histopathological screening of colorectal cancer by Ho, Cowan, Zhao, Zitong, Chen, Xiu Fen, Sauer, Jan, Saraf, Sahil Ajit, Jialdasani, Rajasa, Taghipour, Kaveh, Sathe, Aneesh, Khor, Li-Yan, Lim, Kiat-Hon, Leow, Wei-Qiang

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Functional analysis of germline RAD51C missense variants highlight the role of RAD51C in replication fork protection by Kolinjivadi, Arun Mouli, Chong, Siao Ting, Choudhary, Ramveer, Sankar, Haresh, Chew, Ee Ling, Yeo, Claresta, Chan, Sock Hoai, Ngeow, Joanne

“…Investigations using patient-derived lymphoblastoid cell line carrying heterozygous RAD51C L134S variant showed an impairment in RAD51 chromatin association and replication fork protection, suggestive of deleteriousness of this VUS variant. …”
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Shape morphing of plastic films by Zhang, Feilong, Li, Dong, Wang, Changxian, Liu, Zhihua, Yang, Man, Cui, Zequn, Yi, Junqi, Wang, Ming, Jiang, Ying, Lv, Zhisheng, Wang, Shutao, Gao, Huajian, Chen, Xiaodong

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Constrained neuro fuzzy inference methodology for explainable personalised modelling with applications on gene expression data by Singh, Balkaran, Doborjeh, Maryam, Doborjeh, Zohreh, Budhraja, Sugam, Tan, Samuel, Sumich, Alexander, Goh, Wilson, Lee, Jimmy, Lai, Edmund, Kasabov, Nikola

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Exciton polariton interactions in Van der Waals superlattices at room temperature by Zhao, Jiaxin, Fieramosca, Antonio, Dini, Kevin, Bao, Ruiqi, Du, Wei, Su, Rui, Luo, Yuan, Zhao, Weijie, Sanvitto, Daniele, Liew, Timothy Chi Hin, Xiong, Qihua

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New paths for modelling freshwater nature futures by Kramer, Lilith, Teurlincx, Sven, Rashleigh, Brenda, Janssen, Annette B. G., Janse, Jan H., Brauman, Kate A., Földesi, Csaba, van Wijk, Dianneke, de Senerpont Domis, Lisette N., Patil, Sopan D., Rashidi, Parinaz, Hamel, Perrine, Rising, James, Mooij, Wolf M., Kuiper, Jan J.

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Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

“…Viability of the cells at 7 day-post-infection was 80% - 97% in all conditions tested. In line with published literature, transduction efficiency of neurons at day 14 was found to be 3% - 7% for plasmids containing the SYN1 promoter and 2% - 5% for plasmids containing the CaMKII promoter. …”

Effects of Edible bird's nest on quality of Arabian stallion semen and post-breeding induced endometritis in mares by Al-Khaldi, Khalid Obaid Salim

“…E-Z mixin® treated semen had significantly higher TM, PM, average path velocity (VAP), straight-line velocity (VSL) and curvilinear velocity (VCL) compared to EquiPlus® at either 24 and/or 48 h. …”
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A standardised fraction 1 (SF1) from clinacanthus nutans attenuates the stemness of cervical cancer stem-like cells via inhibition of notch1 signalling by Ismail, Faridah

“…Bioassay guided fractionation was employed for the isolation of SF1 from C. nutans leaf extract. The SiHa cell line was used for the enrichment of CCSCs by culturing the cells in CSC-conditioned medium (cervospheres). …”
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Use of smartphones to detect diabetic retinopathy : scoping review and meta-analysis of diagnostic test accuracy studies by Tan, Choon Han, Kyaw, Bhone Myint, Smith, Helen, Tan, Colin Siang Hui, Car, Lorainne Tudor

“…This review is reported in line with the Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies guidelines. …”
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Individual-fMRI-approaches reveal cerebellum and visual communities to be functionally connected in obsessive compulsive disorder by Kashyap, Rajan, Eng, Goi Khia, Bhattacharjee, Sagarika, Gupta, Bhanu, Ho, Roger, Ho, Cyrus S. H., Zhang, Melvyn, Mahendran, Rathi, Sim, Kang, Chen, Annabel Shen-Hsing

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Plasmonic semiconductor nanogroove array enhanced broad spectral band millimetre and terahertz wave detection by Tong, Jinchao, Suo, Fei, Zhang, Tianning, Huang, Zhiming, Chu, Junhao, Zhang, Dao Hua

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Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods by Lau, Wai-Hoe, White, Nathan J., Yeo, Tsin Wen, Gruen, Russell L., Pervushin, Konstantin

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Atypical DNA methylation, sRNA-size distribution, and female gametogenesis in Utricularia gibba by Cervantes-Pérez, Sergio Alan, Yong-Villalobos, Lenin, Florez-Zapata, Nathalia M. V., Oropeza-Aburto, Araceli, Rico-Reséndiz, Félix, Amasende-Morales, Itzel, Lan, Tianying, Martínez, Octavio, Vielle-Calzada, Jean Philippe, Albert, Victor A., Herrera-Estrella, Luis

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Shaped Bessel beam singulation of glass substrates by Chia, Hao Guang

“…However, the heat generated can cause chipping and debris along the cut line. In addition, the area surrounding the cut often has heat damage, which alters the material's mechanical properties. …”
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Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances by Lim, Hui Kheng, Hughes, Christopher Owen, Lim, Michelle Jing Sin, Li, Jia'En Jasmine, Rakshit, Moumita, Yeo, Calvin, Chng, Kern Rei, Li, Angela, Chan, Joanne Sheot Harn, Ng, Kee Woei, Leavesley, David Ian, Smith, Benjamin Paul Chapman

“…Micronucleus assays typically utilise homogenous in vitro cell lines which poorly recapitulate the physiology, biochemistry and genomic events in the gut, the site of first contact for ingested materials. …”
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Ecosystem productivity has a stronger influence than soil age on surface soil carbon storage across global biomes by Plaza, César, García-Palacios, Pablo, Berhe, Asmeret Asefaw, Barquero, Jesús, Bastida, Felipe, Png, Kenny Guochen, Rey, Ana, Bardgett, Richard D., Delgado-Baquerizo, Manuel

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Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) by Kusuma, Frances Karla, Prabhu, Aishvaryaa, Tieo, Galen, Syed Moiz Ahmed, Dakle, Pushkar, Yong, Wai Khang, Pathak, Elina, Madan, Vikas, Jiang, Yan Yi, Tam, Wai Leong, Kappei, Dennis, Dröge, Peter, Koeffler, H. Phillip, Jeitany, Maya

“…By performing anti-cancer compound library screen on isogenic cell lines and using extrachromosomal telomeric C-circles, as a bona fide marker of ALT activity, we identify a receptor tyrosine kinase inhibitor ponatinib that deregulates ALT mechanisms, induces telomeric dysfunction, reduced ALT-associated telomere synthesis, and targets, in vivo, ALT-positive cells. …”
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