Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers by Takyi-Williams, John

“…The test compound, sunitinib, was stable in all conditions studied and analyte extraction and detection sensitivity could be improved with sufficient off-line or on-line pre-moistening of the dried spot prior to PS-MS analysis after longer storage period. …”
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Investigations into high resolution imaging of the aqueous outflow system and cornea by Hong, Jesmond Xun Jie

“…The imaging probe has resolutions of 10.08 line pairs per mm (~49.61 µm) at the iridocorneal angle region and 5.04 line pairs per mm (~99.21 µm) at the fundus. …”
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Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity by Davey, Curt Alexander, Adhireksan, Zenita, Davey, Gabriela E., Campomanes, Pablo, Groessl, Michael, Clavel, Catherine M., Yu, Haojie, Nazarov, Alexey A., Yeo, Charmian Hui Fang, Ang, Wee Han, Dröge, Peter, Rothlisberger, Ursula, Dyson, Paul J.

“…Using a novel ‘atom-to-cell’ approach, we establish the basis for the surprisingly site-selective adduct formation behaviour and distinct cellular impact of these two chemically similar anticancer agents, which suggests that the cytotoxic effects arise largely from DNA lesions, whereas the protein adducts may be linked to the other therapeutic activities. Our study shows promise for developing new ruthenium drugs, via ligand-based modulation of DNA versus protein binding and thus cytotoxic potential, to target distinguishing epigenetic features of cancer cells.…”
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N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 by Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.

“…Due to its critical role in epigenetics and physiological links to several human diseases, it is also of tremendous biological and medical interest. …”
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Characterization of the biosynthetic gene cluster and shunt products yields insights into the biosynthesis of balmoralmycin by Ma, Guang-Lei, Xin, Lingyi, Liao, Yanghui, Chong, Zhi-Soon, Candra, Hartono, Pang, Li Mei, Lee, Sean Qiu En, Gakuubi, Martin Muthee, Ng, Siew Bee, Liang, Zhao-Xun

“…Balmoralmycin (compound 1) represents a unique group of angucyclines that contain an angular benz[a]anthracene tetracyclic system, a characteristic C-glycosidic bond-linked deoxy-sugar (D-olivose), and an unsaturated fatty acid chain. …”
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Decoding divergence in marine protistan communities: from strain diversity to basin biogeography by Krinos Quinn, Arianna Isabella

“…Scalable workflows highlight the challenge and promise of meta-omic data to link community structure to physiology. I developed a pipeline for metatranscriptome analysis and taxonomic annotation to address the lack of tools built specifically for microbial eukaryotes, and created mock communities to assess recovery success in protistan metatranscriptome analysis workflows (Chapters 4 and 5). …”
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Mechanics of Three-Dimensional Micro-Architected Interpenetrating Phase Composites by Chen, Andrew Y.

“…Altogether, this work broadens our established understanding of the link between architecture and mechanical performance by considering the framework of interpenetrating phase composites, creating the foundation for a new class of strong, resilient, and programmable materials with architected stress states.…”
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LEO satellite formation for SSP : energy and doppler analysis by Goh, Shu Ting, Zekavat, Seyed Alireza, Abdelkhalik, Ossama

“…In this paper, first, the transmission link budget from LEO and geostationary orbits to the Earth are compared, and the harvested energy by the ground station on the Earth is investigated. …”
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Threshold estimation models for linear threshold-based influential user mining in social networks by Talukder, Ashis, Tran, Nguyen H., Niyato, Dusit, Park, Gwan Hoon, Hong, Choong Seon, Mohammad Golam Rabiul Alam

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Distributed hierarchical control of AC microgrid operating in grid-connected, islanded and their transition modes by Hou, Xiaochao, Sun, Yao, Lu, Jinghang, Zhang, Xin, Koh, Leong Hai, Su, Mei, Guerrero, Josep M.

“…In addition, stability analysis is added to facilitate the control parameter designs, and substantial simulation cases are provided to validate the control feasibility, link-failure-resiliency, and plug-and-play capability.…”
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Functional homogeneity and specificity of topological modules in human proteome by Kaalia, Rama, Rajapakse, Jagath Chandana

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Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm by Ng, Calista Keow Leng, Herath, Wishva, Lili, Sun, Hutchins, Andrew P, Robson, Paul, Kolatkar, Prasanna R, Stanton, Lawrence W, Aksoy, Irene, Jauch, Ralf, Chen, Jiaxuan, Dyla, Mateusz, Divakar, Ushashree, Bogu, Gireesh K, Teo, Roy

“…This work provides insights in understanding cell fate transcriptional regulation by highlighting the direct link between the DNA sequence of an enhancer and a developmental outcome.…”
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Review of patency rates between one-stage and two-stage brachial-basilic transposition arteriovenous fistulae creation in an asian population by Lo, Joseph Zhiwen, Yu, Hongyan, Huang, Baoxian, Yau, Joachim Wen Kien, Chandrasekar, Sadhana, Tan, Glenn Wei Leong

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Human comfort in indoor environment : a review on assessment criteria, data collection and data analysis methods by Song, Ying, Mao, Fubing, Liu, Qing

“…Occupants' comfort perception about the indoor environment is closely linked to their health, wellbeing and productivity. …”
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Environmental and human data-driven model based on machine learning for prediction of human comfort by Mao, Fubing, Zhou, Xin, Song, Ying

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Efficient public key encryption with equality test in the standard model by Zhang, Kai, Chen, Jie, Lee, Hyung Tae, Qian, Haifeng, Wang, Huaxiong

“…Then, to prevent adaptive chosen ciphertext attacks (CCA2), we give a link between them by adapting the technique which was originally proposed for identity-based encryption and previously exploited to design efficient CCA2-secure PKE schemes. …”
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Pedestrian heading estimation based on spatial transformer networks and hierarchical LSTM by Wang, Qu, Luo, Haiyong, Ye, Langlang, Men, Aidong, Zhao, Fang, Huang, Yan, Ou, Changhai

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Risk assessment model for UAV cost-effective path planning in urban environments by Hu, Xinting, Pang, Bizhao, Dai, Fuqing, Low, Kin Huat

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Flow network models for online scheduling real-time tasks on multiprocessors by Cho, Hyeonjoong, Easwaran, Arvind

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Smart grid to energy internet : a systematic review of transitioning electricity systems by Joseph, Akhil, Balachandra, Patil

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