Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination by Yong, Hui Yee

“…Next, the encapsulation of ImmRNAs into virus-like particles (VLP) was carried out. The coat protein for two different RNA bacteriophage, MS2 and Q beta were cloned and recombinantly expressed in E.coli. …”
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Template-free formation of uniform urchin-like α-FeOOH hollow spheres with superior capability for water treatment by Wang, Bao, Wu, Hao Bin, Yu, Le, Xu, Rong, Lim, Teik-Thye, Lou, David Xiong Wen

“…Uniform urchin-like α-FeOOH hollow spheres assembled from nanoneedles have been synthesized via a facile and green one-pot method. …”
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CuOx nanotubes via an unusual complexation induced block copolymer-like self-assembly of poly(acrylic acid) by Liang, Yen Nan, Hu, Jinhua, Tam, Michael Kam Chiu, Hu, Xiao

“…Such a unique copolymer-like self-assembly behaviour of the PAA–Cu2+ complex manifests within a specific window of [Cu2+] : [COOH]0 ratio around the binding limit. …”
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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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Like the sea: living communityship as a form of participatory leadership within the creativity for learning in HE (#creativeHE) community by Nerantzi, Chrissi, Gillaspy, Emma, Sinfield, Sandra, Karatsiori, Marianthi, Burns, Tom, Hunter, Anna, Seat, Hannah, Tasler, Nathalie

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Immunotherapy-resistant neuropathic pain and fatigue predict quality-of-life in contactin-associated protein-like 2 antibody disease by Ceronie, B, Strippel, C, Uy, C, Paneva, S, Makuch, M, Soleimani, B, Turaga, S, Binks, S, Ramanathan, S, Michael, S, Varley, J, Easton, A, Themistocleous, A, John Dawes, Bennett, DL, Irani, A, Handel, AE, Irani, SR

“…The long-term clinical outcomes and associated prognostic factors in contactin-associated protein-like 2 (CASPR2)-antibody diseases are unknown. A total of 75 participants with CASPR2 antibodies were longitudinally assessed for disability, quality-of-life, and chronic pain. …”

Nationwide spatial epidemiological dataset of over 100,000 influenza-like illness notifications in Iran by county (2015–2019) by Sedghian, A, MohammadEbrahimi, S, Sartorius, B, Kiani, B

“…Objectives: This data note documents influenza-like illness (ILI) notifications in Iran by county from 2015 to 2019 as a pre-COVID-19 dataset, providing individual and spatial data for further comprehensive spatiotemporal analysis. …”

Development of superhydrophobic ceramic membrane decorated with flake-like structure by two-step synthesis for seawater desalination by membrane distillation by Omar, Najib Meftah Almukhtar, Othman, Mohd. Hafiz Dzarfan, Tai, Zhong Sheng, Puteh, Mohd. Hafiz, Wong, Keng Yinn, Tan, Huiyi, Tonni Agustiono Kurniawan, Tonni Agustiono Kurniawan, Ooi, Boon Seng, Nomura, Mikihiro, Iwamoto, Yuji

“…Significant findings: The results revealed that the MK-SS/4 h HFM, characterized by its flake-like structure, exhibited optimal superhydrophobic behavior. …”

A random-key genetic algorithm-based method for transportation network vulnerability envelope analysis under simultaneous multi-link disruptions by Gu, Y, Ryu, S, Xu, Y, Chen, A, Chan, H-Y, Xu, X

“…This study aims to develop an efficient method based on the random key genetic algorithm (RKGA) for determining the TNVE under simultaneous multi-link disruptions. The main features and benefits of the proposed method include: (a) it simultaneously solves the upper- and lower-bound problems at the same time while guaranteeing the feasibility of all solutions in the solution procedure; (b) it improves the computational efficiency to ensure the applicability to real transportation networks; and (c) it can provide a variety of alternative solutions in addition to the single optimal one, which facilitates the derivation of TNVE buffer and identification of sub-important links. …”

Periodontal disease and serum uric acid levels in the absence of metabolic syndrome: is there a link? A study on a sample of Cameroonian adults by Nkeck, JR, Ndjoh, JJ, Meyo Mvondo, GF, Eko Ondoa, M, Takam, O, Mbouna, SFM, Tcheutchoua Nzokou, D, Tchuisseu-Kwangoua, LA, Momo, CBY, Ekouelkoum Ngoude, JX, Chemgne, MI, Ama Moor, VJ

“…There appears to be no link between SUA and overall periodontal status in this population. …”

Hormone replacement therapy and cancer mortality in women with 17 site-specific cancers: a cohort study using linked medical records by Cardwell, CR, Ranger, TA, Labeit, AM, Coupland, CAC, Hicks, B, Hughes, C, McMenamin, Ú, Mei, XW, Murchie, P, Hippisley-Cox, J

Deactivation of the parvalbumin-positive interneurons in the hippocampus after fear-like behaviour following electrical stimulation of the dorsolateral periaqueductal gray of rats by Temel, Yasin., Blokland, Arjan., Lim, Lee Wei.

“…In conclusion, our findings indicate that the inhibition of this subpopulation of hippocampal parvalbumin-positive interneurons induced a long lasting anxiety- or fear-like behaviour.…”
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The political economy of oil and economic diversification: a neglected research field Robert Mabro would certainly like us to revive by Aissaoui, A

Broadcast Performance Analysis and Improvements of the LTE-V2V Autonomous Mode at Road Intersection by Md. Noor-A-Rahim, G. G. Md. Nawaz Ali, Guan, Yong Liang, Ayalew, Beshah, Chong, Peter Han Joo, Pesch, Dirk

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In situ cross-linked carboxymethyl cellulose-polyethylene glycol binder for improving the long-term cycle life of silicon anodes in Li ion batteries by Lee, Dongsoo, Park, Hyunjung, Goliaszewski, Alan, Byeun, Yun-ki, Song, Taeseup, Paik, Ungyu

“…Through in situ cross-linking during the electrode drying process, the cross-linked CMC-PEG binder is simply prepared without an additional process. …”
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Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration by Goh, Catherine Wenhui, Lee, Irene Chengjie, Sundaram, Jeyapriya Rajameenakshi, George, Simi Elizabeth, Yusoff, Permeen, Brush, Matthew Hayden, Sze, Newman Siu Kwan, Shenolikar, Shirish

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Robust microhoneycomb-like nanofibrous aerogels derived from cellulose and lignin as highly efficient, low-resistant and anti-clogging air filters by Ma, Daphne Xiu Yun, Zeng, Zhihui, Wang, Zhe, Xu, Lulu, Zhang, Youfang, Ang, Jia Ming, Wan, Man Pun, Ng, Bing Feng, Lu, Xuehong

“…In this article, we report highly porous yet robust microhoneycomb-like nanofibrous aerogels (NFAs) with porous cell walls and hierarchical porous structures, and their potential as durable high-performance air filters. …”
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Modern Game Testing : Learn how to test games like a pro, optimize testing effort, and skyrocket your QA career / by Finska, Nikolina, author 656259

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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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Testosterone, sex hormone-binding globulin, insulin-like growth factor-1 and endometrial cancer risk: observational and Mendelian randomization analyses by Mullee, A, Dimou, N, Allen, N, O'Mara, T, Gunter, MJ, Murphy, N

“…<p><strong>Background</strong></p> Dysregulation of endocrine pathways related to steroid and growth hormones may modify endometrial cancer risk; however, prospective data on testosterone, sex hormone-binding globulin (SHBG) and insulin-like growth factor (IGF)−1 are limited. To elucidate the role of these hormones in endometrial cancer risk we conducted complementary observational and Mendelian randomization (MR) analyses. …”