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2561
Immune Checkpoint Blockade sensitivity and Progression-Free Survival associates with baseline CD8+ T cell clone size and cytotoxicity
Published 2021“…The cells contained within the expression matrices and Seurat objects have undergone full pre-processing and QC steps and are used for the analysis and figures in the linked manuscript. For raw data, please refer to the FASTQ files which have been deposited in the European Genome–phenome Archive, which is hosted by the European Bioinformatics Institute and the Centre for Genomic Regulation (accession no. …”
Dataset -
2562
Histone lysine and DNA methylation: dynamic marks in the chromatin
Published 2019“…A common post translational modification is Nε-lysine methylation which is linked to transcriptional silencing or activation depending on the location within the nucleosome. …”
Thesis -
2563
Association between self-reported napping and risk of cardiovascular disease and all-cause mortality: a meta-analysis of cohort studies
Published 2024“…However, napping for 1 hour or more was linked to a 1.37-fold increased risk of CVD (HR: 1.37; 95% CI: 1.09–1.71; I2 = 68.3%; P = 0.007). …”
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Article -
2564
Minimum Wage Policy Effects on Economic Efficiency and Poverty (S/O 12183)
Published 2020“…However, there is no study linking minimum wage on efficiency. Hence, the objective of this study is to analyze the effect of minimum wage policy on a country's efficiency and also its effect on poverty. …”
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Monograph -
2565
Changes in cerebrospinal fluid balance of TNF and TNF receptors in naïve multiple sclerosis patients : early involvement in compartmentalised intrathecal inflammation
Published 2021“…Finally, the CSF TNFR2-associated pattern (encompassing high CSF levels of IFN-β, IFN-λ2, sIL-6Rα) was linked to Th cell differentiation and regulatory cytokine signalling. …”
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Journal Article -
2566
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2022“…We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. …”
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Journal Article -
2567
Lactate cross-feeding between Bifidobacterium species and Megasphaera indica contributes to butyrate formation in the human colonic environment
Published 2024“…Previously, the literature has explicated the butyrate-forming links between Bifidobacterium and Faecalibacterium prausnitzii and between Bifidobacterium and Eubacterium rectale. …”
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Journal Article -
2568
Low magnetic field exposure alters prostate cancer cell properties
Published 2024“…Furthermore, we analysed alterations in matrix metalloproteinases (MMPs) and miRNAs linked to metastasis, as this is crucial in cancer aggressiveness. …”
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Article -
2569
Towards Synergistic Understanding of Language Processing in Biological and Artificial Systems
Published 2024“…Furthermore, the average degree of sentence straightening in the deep layers of the model correlates with corpus-based estimates of sentence surprisal, which are linked to human comprehension difficulty (e.g., as reflected in reading times). …”
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Thesis -
2570
A materials science framework for connecting protein stability with surface adsorption and coating applications
Published 2022“…Although a protein’s conformational stability has been closely linked to its extent of unfolding in the adsorbed state, it remains to be understood how this relationship may be exploited in order to control a protein’s adsorption behavior and adlayer properties to suit specific application needs. …”
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Thesis-Doctor of Philosophy -
2571
Molecular recognition in protein-DNA assemblies
Published 2009“…Distinctions in DNA and nucleosomal site selectivity were apparent between cisplatin and oxaliplatin, which could be linked to differences in their pharmacological profiles. …”
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Research Report -
2572
The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy
Published 2017“…To this end, we used imaging TIRF-fluorescence correlation spectroscopy (ITIR-FCS) to make measurements of fluidity of one bulk membrane probe, DiI, and two ordered/raft-type membrane probes, a transiently expressed GPI-linked GFP and cholera toxin subunit B, on the membranes of living cells that were exposed to Aβ. …”
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Thesis -
2573
Financial elites and the spatial variation of inequality: examining the intersection of gender, race and class in Frankfurt, London, and New York
Published 2021“…Studies investigating the links between diversity and finance originate primarily from behavioural economics or business and management studies. …”
Thesis -
2574
Category learning in infants and adults
Published 2018“…The results revealed that categorisation experience is linked to a modulation of several event-related potentials components suggesting that categorisation may affect visual object processing at an early stage.…”
Thesis -
2575
Metabolic maturation of induced pluripotent stem cells derived cardiomyocytes
Published 2018“…<p>Cardiac metabolism and function are inherently linked, as substrate metabolism generates the energy needed for the heart to beat. …”
Thesis -
2576
Circadian rhythm and misalignment in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD): an experimental medicine approach
Published 2023“…The opening sections of this thesis summarise our existing understanding of the mechanisms driving MASLD, the anatomy and function of the circadian clock, and the links between circadian rhythm and metabolism. I then go on the report data from two bespoke experimental medicine clinical studies: The DECIMAL study (Defining Circadian Metabolism in MASLD) and the MIDNIGHT study (Metabolic Implications of Day and Night-shift working in NHS Healthcare Staff).…”
Thesis -
2577
论明泰昌、天启初年内臣与朝臣的关系 :以宦官王安为例 = The relationship between eunuchs and imperial officials from Ming Tai Chang period to early Tian Qi period : a case study of eunuch Wang An...
Published 2021“…By looking at his career, we can connect the possible links between Wang An and the imperial officials and analyze their relationship. …”
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Final Year Project (FYP) -
2578
The prospective associations of 24-hour movement behaviors and domain-specific activities with executive function and academic achievement among school-aged children in Singapore
Published 2024“…Background: Physical activity (PA), sedentary behavior (SB), and sleep are collectively referred to as 24-h movement behaviors, which may be linked to cognitive development in children. However, most of the evidence was based on cross-sectional studies and/or solely relied on parent-reported information on children’s behaviors, and it remains uncertain whether all domains/contexts of PA and SB are similarly associated with executive function and academic achievement. …”
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Journal Article -
2579
Prospective associations between an empirically derived dietary pattern and life satisfaction in Malaysian adolescents
Published 2024“…Similar RRR analysis was used to find a DP that best explained the variation in response variables linked to poorer life satisfaction, including dietary energy density (DED), fiber density, and percentage of energy from total fat and sugar at the PUTRA-Adol follow-up study. …”
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Article -
2580
High cycle fatigue characterisation and modelling of 316L stainless steel processed by laser powder bed fusion
Published 2020“…In view of the ongoing efforts towards the development of standardised approaches for the determination of suitable processing conditions and part quality for L-PBF-processed parts, this PhD research aims to clarify links of the process-structure-property triad and develop methods for material property assessment. …”
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Thesis-Doctor of Philosophy