Unravelling 2-oxoglutarate turnover and substrate oxidation dynamics in 5-methylcytosine-oxidising TET enzymes by Šimelis, K, Belle, R, Kawamura, A

“…Simultaneous detection of substrate and cofactors is difficult, contributing to a poor understanding of the dynamics between substrate oxidation and 2OG decarboxylation activities. Here, we profile 5-methylcytosine (5mC)-oxidising Ten-Eleven Translocation (TET) enzymes using MS and 1H NMR spectroscopy methods and reveal a high degree of substrate oxidation-independent 2OG turnover under a range of conditions. 2OG decarboxylase activity is substantial (>20% 2OG turned over after 1 h) in the absence of substrate, while, under substrate-saturating conditions, half of total 2OG consumption is uncoupled from substrate oxidation. 2OG kinetics are affected by substrate and non-substrate DNA oligomers, and the sequence-agnostic effects are observed in amoeboflagellate Naegleria gruberi NgTet1 and human TET2. …”

DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts by Kuś, K, Carrique, L, Kecman, T, Fournier, M, Hassanein, SS, Aydin, E, Kilchert, C, Grimes, JM, Vasiljeva, L

“…Xrn2 activity is stimulated by Spt5 to ensure efficient degradation of nascent RNA leading to Pol II dislodgement from DNA. …”

Lasting dynamic effects of the psychedelic 2,5-dimethoxy-4- iodoamphetamine ((±)-DOI) on cognitive flexibility by Sabanovic, M, Lazari, A, Blanco Pozo, M, Tisca, C, Tachrount, M, Martins Bach, A, Lerch, J, Walton, M, Bannerman, D

“…Here we show that a single dose of the psychedelic 2,5-dimethoxy-4-iodoamphetamine ((±)-DOI) affects structural brain plasticity and cognitive flexibility in young adult mice beyond the acute drug experience. …”

Acute inflammatory diseases of the central nervous system after SARS-CoV-2 vaccination by Francis, AG, Elhadd, K, Camera, V, Ferreira Dos Santos, M, Rocchi, C, Adib-Samii, P, Athwal, B, Attfield, K, Barritt, A, Craner, M, Fisniku, L, Iversen, AKN, Leach, O, Matthews, L, Redmond, I, O'Riordan, J, Scalfari, A, Tanasescu, R, Wren, D, Huda, S, Leite, MI, Fugger, L, Palace, J

“…Consequently, the mass SARS-CoV-2 vaccination program could result in increased rates of these conditions. …”

The economic burden of rotavirus hospitalization among children < 5 years of age in selected hospitals in Bangladesh by Ahmed, S, Dorin, F, Satter, SM, Sarker, AR, Sultana, M, Gastanaduy, PA, Parashar, U, Tate, JE, Heffelfinger, JD, Gurley, ES, Khan, JAM

“…<p><strong>Methods</p></strong> We estimated the societal costs of children <5 years for hospitalization from rotavirus gastroenteritis (RVGE) and incidences of catastrophic health expenditure. …”

Northern Borneo stalagmite records reveal West Pacific hydroclimate across MIS 5 and 6 by Carolin, SA, Cobb, KM, Lynch-Stieglitz, J, Moerman, JW, Partin, JW, Lejau, S, Malang, J, Clark, B, Tuen, AA, Adkins, JF

Effect of Co on twin formation and magnetic properties of Sm(Fe,Ti,V)12 alloys by Tozman, P, Hrkac, G, Patrick, CE, Staunton, JB, Saito, T, Sasaki, T, Ohkubo, T, Sepehri-Amin, H

“…Here we have shown that the addition of Co in Sm(Fe_1-xCo_x)_10&ndash;11M_1&ndash;2&nbsp;alloys, where&nbsp;<em>M</em>=Ti and V, leads to an increase in twin density. Microstructural characterizations revealed that the atomic arrangement in the twin boundary changes depending on the stabilizing element, which directly influences the local intrinsic magnetic properties. …”

Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England by Copland, E, Patone, M, Saatci, D, Handunnetthi, L, Hirst, J, Hunt, DPJ, Mills, NL, Moss, P, Sheikh, A, Coupland, CAC, Harnden, A, Robertson, C, Hippisley-Cox, J

“…In 12-17-year-olds, we estimated 3 (95%CI 0–5) and 5 (95%CI 3–6) additional cases of myocarditis per million following a first and second dose with BNT162b2, respectively. …”

Applications of deep learning for physical layer of wireless communication systems by Xie, Yihang

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Milimeter wave patch antenna using thick SU8 photoresist technique / by Basliza Mohamad Noor, 1977-, author 607297, Noor Asniza Murad, supervisor 486393, Fakulti Kejuruteraan Elektrik 540663

Subjects: “…Microwave transmission lines…”

Broadband strip-line ferromagnetic resonance spectroscopy of soft magnetic CoFeTaZr patterned thin films by Jin, Tian Li, Nongjai, R., Asokan, K., Ghosh, A., Aparnadevi, M., Suri, P., Piramanayagam, S. N., Gupta, Surbhi, Kumar, Durgesh

“…In this paper, magnetic and magnetization dynamic properties of compositionally patterned Co46Fe40Ta9Zr5 thin films are investigated. A combination of self-assembly and ion-implantation was employed to locally alter the composition of Co46Fe40Ta9Zr5 thin film in a periodic manner. 20 keV O+ and 60 keV N+ ions were implanted at different doses in order to modify the magnetization dynamic properties of the samples in a controlled fashion. …”
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A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And... by Mhd Rodzi, Nur Anis Raihana

Subjects: “…T11.95-12.5 Industrial directories…”
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Occlusion handling for augmented reality environment using neural network image segmentation: A review. by Ahmad, Muhammad Anwar, Mohd. Suaib, Norhaida, Ismail, Ajune Wanis

Subjects: “…T58.5-58.64 Information technology…”

Game-based augmented reality learning of Sarawak history in enhancing cultural heritage preservation by Clive, Lai Yi Cheng, Goh, Eg Su, Ahmad, Johanna, Tole Sutikno, Tole Sutikno

Subjects: “…T58.5-58.64 Information technology…”
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Predicting child alimony under Islamic shariah law using hybrid fuzzy inference system by Rosili, Nur Aqilah Khadijah, Hassan, Rohayanti, Zakaria, Noor Hidayah, Che Rose, Farid Zamani, Kasim, Shahreen, Tole Sutikno, Tole Sutikno

Subjects: “…T58.5-58.64 Information technology…”
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Hybrid K -means clustering and support vector machine method for via and metal line detections in delayered IC images by Cheng, Deruo, Shi, Yiqiong, Lin, Tong, Gwee, Bah-Hwee, Toh, Kar-Ann

“…This brief proposes a hybrid K-means clustering and support vector machine (HKCSVM) method to detect the positions of vias and metal lines from delayered IC images for subsequent netlist extraction. …”
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Double periodic composite right/left handed transmission line based leaky wave antenna by singular perturbation method by Mujumdar, Manisha D., Jin, Cheng, Alphones, Arokiaswami

“…The paper proposes a Composite Right/Left Handed double periodic transmission line structure with both inductance and capacitance loaded. …”
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Tree-ring δ 18 O and δ 2 H stable isotopes reflect the global meteoric water line by Arosio, T, Büntgen, U, Nicolussi, K, Moseley, GE, Saurer, M, Pichler, T, Smith, MP, Gutierrez, E, Andreu-Hayles, L, Hajdas, I, Bebchuk, T, Leuenberger, M

“…Introduction: The Global Meteoric Water Line (GMWL) describes the linear relationship between stable hydrogen (δ 2H) and oxygen (δ 18O) isotopes in precipitation over large spatial scales and therefore represents a unique reference for water isotopic values. …”

Measurement of the top quark mass using a profile likelihood approach with the lepton + jets final states in proton–proton collisions at $$\sqrt{s}=13\,\text {Te}\hspace{-.08em}\text {V} $$ s = 13 Te V by Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Del Valle, A. E., Hussain, P. S., Jeitler, M., Krammer, N., Lechner, L., Liko, D., Mikulec, I., Paulitsch, P., Pitters, F. M., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M.

“…The top quark mass is measured to be $$171.77\pm 0.37\,\text {Ge}\hspace{-.08em}\text {V} $$ 171.77 ± 0.37 Ge V . …”
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Product Construction of Affine Codes by Chee, Yeow Meng, Kiah, Han Mao, Purkayastha, Punarbasu, Solé, Patrick

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