Developing small molecule ligands for the study of bromodomain-histone interactions by Brand, M

“…The stability of the dihydroquinaxolinone headgroup was optimised by ring size expansion, which maintained CREBBP affinity and binding mode – the latter of which was confirmed by X-Ray crystallography. …”

Resolution of proteotoxic stress in the endoplasmic reticulum by ubiquitin ligase complexes by Lari, F

“…ER-associated degradation (ERAD) oversees protein folding and delivers misfolded proteins for degradation by the proteasome via ubiquitin conjugation mediated by RING-type E3 ubiquitin ligases. An intact ERAD is crucial to cellular homeostasis, as unresolved protein imbalances cause ER stress that ultimately lead to apoptosis. …”

Synthesis and properties of porphyrin nanotubes by Haver, R

“…An unprecedented method of ring-stacking of pre-formed 6-porphyrin nanorings is discussed as well as a template-directed procedure. …”

Quality seaport : model building and empirical validation by Phang, Louise Foong Hung.

“…The survey was sent out to a total of 350 Freight Forwarders, Shipping Lines and Cargo Owners who are main users of the Singapore Port that we are focusing our study on for simplification purposes. …”
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The development and application of mass-spectrometry-based tools to monitor proteome remodeling in microbes by Telusma, Bertina

“…Although each pathway will contribute, ultimately, whether cells mount a response primarily driven by synthesis or by degradation hinges on the nature and duration of the stress, as well as the cell type involved. …”
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Injectable cell transplantation system for cytokine-based cancer immunotherapy by Gerard Nathanael Adrianus.

“…The construct was able to exert toxicity to two malignant cell lines, MCF-7 and HepG2, but no effect was observed in HeLa and H1229 cells. …”
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Evaluation and selection of rice mutants for high yield and quality fodder production by Abisola, Oladosu Yusuff

“…Evaluation over two locations, mutant lines ML21, ML10, ML4, ML6 and ML9 performed better in terms of yield production compared to other mutants. …”
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WHISPERS OF THE WIND / by Grace, Jeyna, author 655424

“…From the hazardous trip behind enemy lines to the festive East Asian-esque Meihua; from the kingdom hovering above the clouds to the military-driven Bevattna; from the heterogeneous society of a tunnelled realm to Aithan’s duel with the heir of Tentazoa, every step in his journey uncovers a gem of his past, present, and future. …”

End-to-end simulation of high-contrast imaging systems: methods and results for the PICTURE mission family by Douglas, Ewan S., Hewawasam, Kuravi, Mendillo, Christopher B., Cahoy, Kerri L, Cook, Timothy A., Finn, Susanna C. Finn, Howe, Glenn A., Kuchner, Marc, J., Lewis, Nikole K., Marinan, Anne D., Mawet, Dimitri, Chakrabarti, Supriya

“…Simulated science observations of the predicted warm ring around Epsilon Eridani illustrate the performance of both missions.…”
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Comparative analysis of changes in retinal layer thickness following femtosecond laser-assisted cataract surgery and conventional cataract surgery by Surl, Dongheon, Kim, Seungmin, Kim, Sangyeop, Kim, Tae-Im, Seo, Kyoung Yul, Jun, Ikhyun

“…The average retinal thickness of the four inner macular ring quadrants was used for comparative analysis. …”
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Temperature and burning history affect emissions of greenhouse gases and aerosol particles from tropical peatland fire by Kuwata, Mikinori, Kai, Fuu Ming, Yang, Liudongqing, Itoh, Masayuki, Gunawan, Haris, Harvey, Charles F.

“…Mass spectrometric analysis of organic components indicated that aerosol particles emitted at higher temperatures had more unsaturated bonds and ring structures than that emitted from cooler fires. …”
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Mechanical and microstructural characteristics of high-strength self-compacting concrete (HSSCC) with optimal silica fume and fly ash cement replacement by Aliyu Azare, Ahmed, Mohd Haziman, Wan Ibrahim, Faisal Alshalif, Alshalif, Putra Jaya, Ramadhansyah, Nindyawati, Nindyawati

“…These aspects entailed fresh properties’ verification, slump flow, T500, J-ring, segregation resistance, and compressive strength on newly incorporated properties. …”
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Nanothermite composites with a novel cast curable fluoropolymer by Nie, Hongqi, Tan, Li Ping, Pisharath, Sreekumar, Hng, Huey Hoon

“…Herein, we report the synthesis of a novel cast curable fluoropolymer (FP) with 58 wt% fluorine content produced through the cationic ring opening polymerization of 3-Perfluorohexyl-1, 2-epoxypropane. …”
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Gold-catalyzed intramolecular animation of alcohol pro-electrophiles as novel synthetic strategies to nitrogen heterocycles by Prasath Kothandaraman

“…In Chapter V, gold-catalyzed tandem ring opening/amination of secondary and tertiary 2-tosylaminophenylcyclopropyl carbinols is introduced as an efficient synthetic route to 2,3-dihydro-1H-benzo[b]azepines as well as 2-vinylindolines. …”
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Chris Ryan Extreme : Night Strike / by Ryan, Chris, author 329350

“…Shadowed every step of the way by a ruthless CIA hitman, Bald soon finds that the lines between friend and enemy are blurred, and he'll have to call on all his warrior instincts to stay alive...…”

Dealing, music and youth violence: neighbourhood relational change, isolation and youth criminality by Alexander, James

“…The study considers the emergence of drill music, county lines and the lowering of the threshold of when weapons are used to explore the isolated social environments so many young people find themselves in. …”
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A wireless, battery-free device enables oxygen generation and immune protection of therapeutic xenotransplants in vivo by Krishnan, Siddharth R, Liu, Claudia, Bochenek, Matthew A, Bose, Suman, Khatib, Nima, Walters, Ben, O’Keeffe, Laura, Facklam, Amanda, Langer, Robert, Anderson, Daniel G

“…Through systematic in vitro studies with primary cell lines and cell lines engineered to secrete protein, we demonstrate device performance in preventing hypoxia in ambient oxygen concentrations as low as 0.5%. …”
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Petrogenesis of the Deccan high-Mg basalts and picrites by Chatterjee, Nilanjan

“…A picrite and two very high-Mg basalts plot on their olivine control lines. So, their primary magmas were calculated by adding only equilibrium olivine. …”
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The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy by Ng, Justin Wei Qing

“…Although there have been several studies done regarding this topic, the results have been conflicting and thus inconclusive, likely due to the drawbacks and biases introduced by techniques used in those studies. …”
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Smart panels for sunlight management and energy harvesting by Wee, Samuel Xin An

“…In this study, we report various methods to tackle the challenges of uniformity and safety issues. Conductive lines are introduced to improve the current density distribution and various polymers and their polymerization are investigated to reduce the risk of leakage and flammability. …”
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