Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…We validate this technology with the rapid generation of three BCR KI lines expressing native human precursors, instead of computationally inferred germline sequences, to HIV broadly neutralizing antibodies. …”
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Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells by Wang, Ruoxi W., Viganò, Sonia, Ben-David, Uri, Amon, Angelika, Santaguida, Stefano

“…Inactivating NF‐κB abolishes NK cell‐mediated clearance of untransformed aneuploid cells. In cancer cell lines, NF‐κB upregulation also correlates with the degree of aneuploidy. …”
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How information about historic carbon emissions affects support for climate aid: evidence from a survey experiment by Charnysh, Volha, Kalow, Jared, Lieberman, Evan, Walk, Erin

“…However, in democratic countries such as the United States, it remains uncertain whether such messages can affect public opinion, especially across partisan lines. We conducted a pre-registered survey from a national online pool (N = 5,002) with a built-in experiment to evaluate the effectiveness of alternative communications strategies associated with historic carbon emissions in increasing support for climate aid. …”
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A novel low-crosstalk driveline based on spoof surface plasmon polaritons by Zhao, Shumin, Zhang, Hao Chi, Liu, Liangliang, Zhao, Jiahao, Yang, Cheng

“…By using traditional drivelines, for example, microstrip lines, the distance between adjacent drivelines should be large enough to reduce the multichannel coupling effects. …”
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Fullwave modeling of coplanar-waveguide discontinuities for applications in filter design and metamaterial characterization by Gao, Jing

“…Coplanar waveguide (CPW) has been finding wide applications in microwave integrated circuit (MIC) and monolithic microwave integrated circuit (MMIC) due to several advantages it offers over microstrip lines. Typical discontinuities characteristics are an integral part of practical circuit design. …”
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New techniques for automated architectural reconstruction from photographs by Werner, T, Zisserman, A

“…Second, we develop and refine a technique for piecewise planar model fitting involving sweeping polygonal primitives, and assess the performance of this technique. Third, lines at infinity are constructed from image correspondences and used to sweep planes in the principal directions. …”

Integrative taxonomy clarifies the evolution of a cryptic primate clade by van Elst, T, Sgarlata, GM, Schüßler, D, Tiley, GP, Poelstra, JW, Scheumann, M, Blanco, MB, Aleixo-Pais, IG, Rina Evasoa, M, Ganzhorn, JU, Goodman, SM, Hasiniaina, AF, Hending, D, Hohenlohe, PA, Ibouroi, MT, Iribar, A, Jan, F, Kappeler, PM, Le Pors, B, Manzi, S, Olivieri, G, Rakotonanahary, AN, Rakotondranary, SJ, Rakotondravony, R

“…Here we illustrate best practices for clarifying cryptic diversification processes by presenting an integrative framework that leverages multiple lines of evidence and taxon-informed cut-offs for species delimitation, while placing special emphasis on identifying patterns of isolation by distance. …”

Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines by Stanslas, Johnson, Hagan, Damien J., Ellis, Michael J., Turner, Claire, Carmichael, James, Ward, Wynne, Hammonds, Timothy R., Stevens, Malcolm F. G.

“…The novel water-soluble agent dihydroindolizino[7,6,5-kl]acridinium chloride 14 has inhibitory activity in a panel of non-small-cell lung and breast tumor cell lines exceeding that of m-AMSA. The salt inhibited the release of minicircle products of kDNA confirming that disorganization of topoisomerase II partly underlies the activity of the compound. …”

JIT manufacturing : a case study by Ghim, Boey Cheng, Foo, Shar Kee, Tan, Cheng Teck

“…But, studies have shown that companies jumping hastily into the bandwagon of JIT manufacturing are more likely to face difficulties and fail in their attempts. …”
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COVID-19 pandemic impact on hypertension management in North East London: an observational cohort study using electronic health records by Rison, SCG, Redfern, O, Mathur, R, Dostal, I, Carvalho, C, Raisi-Estabragh, Z, Robson, JP

“…Conversely, the Asian ethnic group was more likely to have controlled blood pressure (ORs 1.09 (95% CI 1.05 to 1.14, p<0.001) to 1.28 (95% CI 1.23 to 1.32, p<0.001)). …”

Study of financial performance of China companies listed on Singapore Stock Exchange by Chua, Kenneth, Ding, Lit Yong, Wong, Kai Yuan

“…Before comparing key financial ratios, we review the listing requirements of regional stock exchanges that China companies are mostly likely to list on to understand the reason why SGX is becoming a popular choice for China companies.…”
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Service quality in the Singapore mobile phone industry after 1 April 2000 : the consumer's perspective. by Phua, Kevin Tshi Howe., Koh, Kok Beng., Goh, Jayson Chor Hong.

“…Compares among the 3 market players: SingTel, M1 and StarHub; and attempts to highlight the possible actions likely to be taken by dissatisfied customers.…”
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Cellular reporter for inflammation. by Yuhanis Abdullah Sunny.

“…Currently, there are commercial green fluorescent protein (GFP) assays available for in vitro cell lines only. There are no in vivo systems that can report NF-B activation in hematopoietic stem cells. …”
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Laser surface treatment of 50CrMo4 steel by Chew, Han Xin

“…The speed of laser is significance in affecting the width and depth of the laser treated lines. When the speed is too high, the change is not visible, thus, the hardness test cannot be done on the cross section area.…”
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COVID-19 policy analysis: labour structure dictates lockdown mobility behaviour by Heroy, Samuel, Loaiza, Isabella, Pentland, Alex, O’Clery, Neave

“…Within cities, wealthier residents are more likely to reduce mobility, and commuters are especially more likely to stay at home when their work is located in wealthy or commercially/industrially formalized neighbourhoods. …”
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Probabilistic classification criterion for failure modes of reinforced concrete columns by Yu, Bo, Yu, Zecheng, Li, Bing, Li, Qiming, Ning, Chaolie

“…A probabilistic classification criterion was proposed to classify likely failure modes of reinforced concrete (RC) columns under seismic loading conditions. …”
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The roles of source expertise and message completeness in the evaluation of an online health discussion board. by Thanomwong Poorisat.

“…Further analyses show that when the message lacked explanation, low task importance participants were likely to use an expertise heuristic to infer message credibility. …”
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He's my man : effect of female competition on female gift choices for male partner by Woo, Yue Ting

“…It was hypothesized that participants who were primed with intra-sexual competition, as compared to those who were not, would be (1) less likely to prefer appearance-enhancing products as gifts for their boyfriends and (2) more likely to prefer appearance-downgrading products for the same purpose. …”
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Diving behaviour of benthic feeding Black Guillemots by Shoji, A, Elliott, KH, Greenwood, JG, McClean, L, Leonard, K, Perrins, CM, Fayet, A, Guilford, T

“…</p> <p><strong>Conclusions</strong> Black Guillemots' dive duration was similar to the value predicted from allometry, and is therefore likely representative of this species. Bathymetry likely influences the dive behaviour of this benthic-feeding species because most dives were U-shaped and dive depths were shallow, which is typical for the relatively shallow water where the birds were observed foraging.…”

Quantifying the Evolutionary Dynamics of Structure and Content in Closely Related E. coli Genomes by Molari, M, Shaw, LP, Neher, RA

“…We comprehensively describe genome evolution within n=222 genomes of Escherichia coli ST131, which likely shared a common ancestor around 100 years ago. …”