Developing optogenetics for use in vascular research by Rorsman, N

“…The overall aim of this thesis was to establish ChR2 for use in vascular optogenetics. The main findings of this thesis are:</p> <p>1) Blue light activation of ChR2 and the ChR2 variant ChR2(H134R) led to long-lasting and non-inactivating depolarising currents. …”

Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…</p> <br> <p><strong>Findings:</strong> We sequenced 731 genomes from isolates obtained during surveillance across the three sites between Oct 1, 2016, and Aug 31, 2019 (24 months in Dhaka and Kathmandu and 34 months in Blantyre). …”

Development and characterization of collagen type I and hyaluronic acid (HA) based interlaced scaffolds for tissue engineered heart valves (TEHVS) by Nazir, R

“…While evaluated against the criterion for tissue engineered heart valve (TEHV), S-3 and S-4 among interlaced scaffolds/compositions not only matched mechanically but also showed high degradation resistance which potentially made them as '<b>close-fit</b>' candidates. Findings from this thesis indicated that collagen/HA interlaced scaffolds have the potential to fill in the niche for designing an ideal TEHV. …”

The influence of pregnancy complications on fetal and neonatal cardiovascular development by Aye, C

“…As up to 8% of pregnancies are affected by hypertensive disorders of pregnancy and approximately 10% of all births are preterm, understanding the mechanisms behind these findings and their relevance to long term cardiovascular disease in this population is of great public health interest. …”

Prevalence of offering menopause hormone therapy among primary care doctors and its associated factors: a cross-sectional study by Low, Tiong Lim, Cheong, Ai Theng, Devaraj, Navin Kumar, Ismail, Rohayah

“…Conclusion The study revealed a low rate of MHT prescription among PCDs, with many relying on referrals to hospitals for managing menopausal symptoms. The findings underscore the need for strategies that includes fulfilling professional training gaps, improving MHT availability, and improving information dissemination for patient. © 2024 Low et al. …”
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Relationship of sperm protamine content with bull breeding soundness evaluation and sperm DNA damage by Mohamed Abbad Alfadel, Fatima

“…Post hoc pairwise comparison showed an increased DNA damage in bulls with lower protamine values. The findings of this study concluded that sperm protamine can be used as a useful biomarker to predict semen quality and male potential fertility. …”
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Implementation of occupational safety and health management system in reducing ergonomic risk among certified and uncertified automotive industry workers by Ikpegbu, Mavis Amarachi

“…The data generated was statistically analyzed using SPSS version 21.0 and the finding revealed that workers in OSH certified company had a significant lower score for back posture of 14.07±1.584 compared to the workers in uncertified company 15.49±1.566, also mean values of shoulder/arm posture,wrist/hand postures and neck posture among the workers of the OSH certified company were 15.95±2.219, 15.48±1.190 and 7.13±1.053 respectively, which was significantly lower compared to the workers of the uncertified automotive company, who scored 18.94±1.943, 16.29±1.123 and 7.82±0.574, respectively. …”
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RNA interference silencing of interleukin-6 in mesenchymal stromal cells and antitumour efficacy against multiple myeloma cells by Teoh, Hoon Koon

“…In conclusion, both RNAi pathways were equally effective in suppressing IL-6 expression in MSC and displayed in vitro and in vivo antitumor efficacy against U266 cells. These findings support the feasibility of using RNAi as an alternative approach for targeted suppression of IL-6 in MSC to inhibit multiple myeloma cell growth.…”
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Savings and Investment Behaviour of the Consumer of Financial Services and Their Service Expectations from Banks (S/O 12349) by Ahmad, Nor Hayati, Saha, Asish, Eam, Lim Hock, Katib, Mohamed Nasser, Musa, Muhammad Muhaizam, Yeok, Siew Goh

“…Another significant findings based on logit model to estimate the predicted probability of the relative quality of customer service shows CIMB customers are less satisfied with the location, employee responsiveness, and administrative effectiveness. …”
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Behind the Two-Wheeled Vehicle: Understanding Riders' Behaviour in School Zones (S/O: 13058) by Abdul Hanan, Suhaila, Zainuddin, Nizamuddin, King, Mark, Lewis, Ioni

“…This most probably because school zones are congested with traffic, thus, the motorcyclists may ride safely and comply with the SZSL regardless the other things. Overall, the findings provide support for the application of the TPB to understand motorcyclists intention and behaviour in school zones. …”
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Developing a Household Flood Vulnerability Index for Managing the Risk of Flood Disasters (S/O 13584) by Hassan, Sallahuddin, Abu Bakar, Arpah, Othman, Zalila, Khalid, Mohamad Sukeri, Abu Talib, Mansor

“…While floods cannot be fully prevented despite recent developments in infrastructures, preparedness, recovery and response, enhancing community resilience is therefore needed to be a priority in flood-prone communities. The findings of this study tend to vary by the district and state, accordingly. …”
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基于经验模态分解和神经网络的微网混合储能容量优化配置 = Capacity optimization of hybrid energy storage systems in microgrid using empirical mode decomposition and neural network... by 孙承晨 Sun Chengchen, 袁越 Yuan Yue, Choi, San Shing, 李梦婷 Li Mengting, 张新松 Zhang Xinsong, 曹阳 Cao Yang

“…A neural network model is utilized to determine the capacity of the HESS through finding a compromise between the cost of the system and the LOS of the power. …”
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Colon Cancer Disparities in Stage at Presentation and Time to Surgery for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study with Disaggregated Ethnic Groups by Jain, Bhav, Bajaj, Simar S., Patel, Tej A., Vapiwala, Neha, Lam, Miranda B., Mahal, Brandon A., Muralidhar, Vinayak, Amen, Troy B., Nguyen, Paul L., Sanford, Nina N., Dee, Edward C.

“…Conclusions Our findings reveal key disparities in stage at presentation and time to surgery by race/ethnicity among AANHPI subgroups. …”
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Mechanistic Studies of Interfacial Proton-Coupled Electron Transfer to Molecularly Defined Surface Sites by Lewis, Noah B.

“…With these observations we construct a mechanistic model in which I-PCET is not a single step, but a multi-step reaction sequence in which elementary I-PCET is gated by an ion exchange reaction between proton donor/acceptor species and proton-neutral supporting electrolyte at the electrode-electrolyte interface. These findings demonstrate how supporting electrolyte can be leveraged as a design parameter to independently control electrolyte pH and the rates of I-PCET-based reactions.…”
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GPU-Oriented Algorithms for Continuous Energy Monte Carlo Neutron Transport by Ridley, Gavin

“…We then present a specialized root-finding algorithm that takes advantage of the structure of the problem to efficiently sample the resonance upscatter effect on GPUs. …”
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Interaction of TiO2 and ZnO NPs with human skin cells by Gautam, Archana

“…Therefore, the goal of this study is to assess the physiological effects of TiO2 and ZnO NPs interactions with primary human epidermal keratinocytes and dermal fibroblasts, with attention to accurate dosimetry measurements and particle solubility considerations. Since the current findings on NPs interaction with skin cells are mostly based on 2D monolayer cell culture and animal models, in this study, 3D human skin explants have also been used to better understand the effects of NPs in the skin tissue. …”
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发达地区失地老人养老支持体系内卷化及其突破 — 基于苏州市的个案研究 = The involution of the eldercare system for the landless elderly in China’s developed regions : a case study based on Suzhou municipality... by 叶继红 Ye Jihong, 占少华 Zhan Shaohua

“…This article, based on an analysis of a “rural to residential”community in Suzhou Municipality, Jiangsu Province, finds that land acquisition has generated a strong impact on the life and pension style of the landless elderly. …”
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Analysis of lava flow impacts for use in risk assessments by Meredith, Elinor Siwan

“…Along with the 2018 Kīlauea assessment, I used this compiled dataset to assess relationships between lava flow thickness as a proxy for hazard intensity and damage severity, presenting the first empirically-derived and non-linear fragility functions for lava flow structure damage, for different structure types. The findings show a recent increase in recorded impact events, and that these events occur more frequently than previously thought, with almost three impact events, to population centres, per decade in the past 100 years. …”
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Mechanics in dehydration-induced leaf morphing behaviors by Guo, Kexin

“…This thesis focuses on three shape-morphing phenomena observed in plant leaves as passive responses to the strain mismatch caused by dehydration. The research findings indicate the significant influence of mechanics on the formation of leaf shapes. …”
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Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore by Lim, Jue Tao, Bansal, Somya, Chong, Chee Seng, Dickens, Borame, Ng, Youming, Deng, Lu, Lee, Caleb, Tan, Li Yun, Chain, Grace, Ma, Pei, Sim, Shuzhen, Tan, Cheong Huat, Cook, Alex R., Ng, Lee Ching

“…To compare interventions, we used the synthetic control method to generate appropriate counterfactuals for the intervention towns using a weighted combination of 30 control towns between EW 1, 2014 and EW 26, 2022. Findings: Our study comprised an at-risk population of 607 872 individuals living in intervention sites and 3 894 544 individuals living in control sites. …”
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