Metabolic maturation of induced pluripotent stem cells derived cardiomyocytes by Lopez, C

“…By simultaneously targeting both maturation methods we have shown a degree of maturation through an increased movement towards reduced glycolysis and increased FAO in our iPSC-CMs.</p> <p>Like others this thesis has shown that iPSC-CMs mature slowly over time with changes in structural genes occurring during the first month of differentiation and continuing to increase up to 3 months, whereas metabolic changes took longer to develop. 3D culture on collagen-derived scaffolds and engineered heart tissue (EHT) accelerated this maturation time and increased mitochondrial oxidative metabolism while decreasing anaerobic glycolysis. …”

Molecular characterisation of methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in cats, dogs and pet owners in a Veterinary Hospital by Afshar, Mohammad Farzad

“…Having close contact with animals like allowing them to lick face and having other animals had a significant association with carriage of staphylococci in this study. …”
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Impact of BPL penalty functions and PSF models in PET/CT radial spatial resolution recovery by Si, Wang Jie

“…Advanced reconstruction algorithms like TOF, BPL, and PSF models, along with OSEM have shown spatial resolution enhancements based on the FWHM measured. …”
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Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition by Flower, Cameron Timothy

“…By leveraging targeted and untargeted mass spectrometry (MS) of endogenous tyrosine-phosphorylated proteins, which enables phosphosite-specific quantification of TK signaling networks, I report several cell line-specific vulnerabilities not predicted to exist at the genetic level, and the consensus observation that sustained activity of SRC family kinases (SFKs), or of the SRC-like kinases ABL1/2, is an important contributor to GM-TKI tolerance in all lines. …”
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Fluid-fluid displacement in porous-media microfluidics by Qiu, Yu

“…Many questions remain, however, regarding how the macroscopic displacement patterns are controlled by the microscale interactions between the fluid interface and the solid surface in systems under geometric confinement like microfluidic devices and porous media. This fluid-solid interaction—exacerbated by the roughness inherent to all natural and engineered surfaces—introduces a large energy dissipation near the solid boundary that challenges our ability to interpret laboratory experiments and develop mathematical models. …”
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Smart window for tuning transparency and noise absorption by Shrestha, Milan

“…As a tunable optical surface scatter, it turns transparent with a smooth surface like a flat glass; but it turns ‘opaque’ (translucent) with the micro-rough surface. …”
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VR-CFD : interactive simulation of computational fluid dynamics by Yang, Sida

“…The developed VR-CFD application utilized an attractive design with bright colours, familiar game characters and game-like user interface aimed to make the introductory CFD class fun, interactive and engaging, helping students intuitively grasp the physics concepts. …”
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Phase transitions by an abundant protein in the anammox extracellular matrix mediate cell-to-cell aggregation and biofilm formation by Seviour, Thomas, Wong, Lan Li, Lu, Yang, Mugunthan, Sudarsan, Yang, Qiaohui, Chanda Segaran, Uma Shankari, Bessarab, Irina, Liebl, David, Williams, Rohan B. H., Law, Yingyu, Kjelleberg, Staffan

“…The Brosi_A1236 structure was computationally predicted to consist of immunoglobulin-like anti-parallel β-strands, and circular dichroism conducted on the isolated surface protein indicated that β-strands are the dominant higher-order structure. …”
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An NKX2-1GFP and TP63tdTomato dual fluorescent reporter for the investigation of human lung basal cell biology by Goh, Kim Jee, Tan, Ee Kim, Lu, Hao, Roy, Sudipto, Dunn, Norris Ray

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Functional metagenomic analysis of quorum sensing signaling in a nitrifying community by Tan, Chuan Hao, Yeo, Yee Phan, Muhammad Hafiz Ismail, Ng, Noele Kai Jing, Subramoni, Sujatha, Taj, Shireen, Tay, Martin, Chao, Xie, Kjelleberg, Staffan, Rice, Scott A.

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Cryogelation of human hair keratins by Chua, Huei Min

“…Microarchitecture analysis revealed that FT cycling rendered a change from sheet-like lamellae in FT0 sponges to interconnected polygonal pores in freeze-thawed sponges. …”
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High mobility 3D Dirac semimetal (Cd₃As₂) for ultrafast photoactive terahertz photonics by Dai, Zijie, Manjappa, Manukumara, Yang, Yunkun, Tan, Thomas CaiWei, Qiang, Bo, Han, Song, Wong, Liang Jie, Xiu, Faxian, Liu, Weiwei, Singh, Ranjan

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The hazards of unconfined pyroclastic density currents: a new synthesis and classification according to their deposits, dynamics, and thermal and impact characteristics by Lerner, Geoffrey A., Jenkins, Susanna F., Charbonnier, Sylvain J., Komorowsk, Jean-Christophe, Baxter, Peter J.

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Alkali additives enable efficient large area (>55 cm²) slot-die coated perovskite solar modules by Rana, Prem Jyoti Singh, Febriansyah, Benny, Koh, Teck Min, Bening Tirta Muhammad, Salim, Teddy, Hooper, Thomas J. N., Kanwat, Anil, Ghosh, Biplab, Kajal, Priyanka, Lew, Jia Haur, Aw, Yeow Chong, Yantara, Natalia, Bruno, Annalisa, Pullarkat, Sumod A., Ager, Joel W., Leong, Wei Lin, Mhaisalkar, Subodh Gautam, Mathews, Nripan

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Chitosan nanofibrous scaffold with graded and controlled release of ciprofloxacin and BMP-2 nanoparticles for the conception of bone regeneration by Zhang, Sihan, Zhao, Guanglei, Mahotra, Manish, Ma, Shiyuan, Li, Wenrui, Lee, Hiang Wee, Yu, Hong, Sampathkumar, Kaarunya, Xie, Denghui, Guo, Jinshan, Loo, Joachim Say Chye

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Free-electron crystals for enhanced X-ray radiation by Wong, Wesley Lee Wei, Shi, Xihang, Karnieli, Aviv, Lim, Jeremy, Kumar, Suraj, Carbajo, Sergio, Kaminer, Ido, Wong, Liang Jie

“…Our work highlights an unprecedented regime of free electron light emission where electron waveshaping provides multi-dimensional control over practical radiation processes like bremsstrahlung. Our results pave the way towards greater versatility in table-top X-ray sources and improved fundamental understanding of quantum electron-light interactions.…”
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Thermally induced phase separation PVDF membrane fabricated by using NaCl coagulation bath: relation of membrane surface morphology and permeation performance by Chen, Ningyuan, Zhao, Jie, Shi, Lei, Goto, Atsushi, Wang, Rong

“…As the NaCl concentration increases in the coagulation bath, the outer surface of the fabricated membrane transited from a mesh-like structure to a spherulite structure. As 0.5 mol L−1 NaCl was added to the coagulation bath, the membranes displayed a pure water permeability of 1073.9 L m−2 h−1 bar−1 while maintaining a narrow pore size distribution. …”
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Information retrieval and multimodal sentiment analysis for climate change by Duong, Cuc Thi Kim

“…The Intergovernmental Panel on Climate Change (IPCC) has affirmed that human activities persist in elevating the global mean temperature, altering extreme weather patterns like heatwaves, droughts, tropical cyclones, and heavy rainfall. …”
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The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

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The stalks of the motor A1A0 ATP synthase come into the focus : structural insight into subunits E, F and H by Gayen, Shovanlal

“…The protein is dimeric and has a boomerang-like shape, composed of two arms of 12.0 and 6.8 nm in length. …”
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