Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
Get full text

Testosterone, sex hormone-binding globulin, insulin-like growth factor-1 and endometrial cancer risk: observational and Mendelian randomization analyses by Mullee, A, Dimou, N, Allen, N, O'Mara, T, Gunter, MJ, Murphy, N

“…<p><strong>Background</strong></p> Dysregulation of endocrine pathways related to steroid and growth hormones may modify endometrial cancer risk; however, prospective data on testosterone, sex hormone-binding globulin (SHBG) and insulin-like growth factor (IGF)−1 are limited. To elucidate the role of these hormones in endometrial cancer risk we conducted complementary observational and Mendelian randomization (MR) analyses. …”

Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice by Mohd Kasim, Vivi Nur Khalieda, Lee, Yu Zhao, Bakrin, Ikmal Hisyam, Hussain, Mohd Khairi, Israf, Daud Ahmad, Shaari, Khozirah, Tan, Ji Wei, Lee, Ming Tatt, Tham, Chau Ling

“…Using a mouse DNCB-induced AD-like skin lesions model, this study evaluated the potential therapeutic utility of tHGA as an oral and topical treatment for AD. …”
Get full text

When a test is more than just a test: findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial) by Brown, S, Ploeger, C, Guo, B, Petersen, JJ, Beckenstrom, AC, Browning, M, Dawson, GR, Deckert, J, Dias, R, Dourish, CT, Gorwood, P, Kingslake, J, Menke, A, Sola, VP, Reif, A, Ruhe, H, Simon, J, Stäblein, M, van Schaik, A, Veltman, DJ, Morriss, R, PReDicT Group

Counterproductive effects of anti-CD38 and checkpoint inhibitor for the treatment of NK/T cell lymphoma by Lee, Wendy W. L., Lim, Jing Quan, Tang, Tiffany Pooi Ling, Tan, Daryl, Koh, Ser Mei, Puan, Kia Joo, Wang, Liang Wei, Lim, Jackwee, Tan, Kim Peng, Chng, Wee Joo, Lim, Soon Thye, Ong, Choon Kiat, Rotzschke, Olaf

Subjects: “…Medicine, Health and Life Sciences…”
Get full text

Over the top : moving from survival to stability, from stability to success, from success to significance / by Ziglar, Zig, 1926-2012 456132

Subjects:

Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
Get full text

Program Skill for Life mantapkan kemahiran tatarias wajah mahasiswa UMPSA agar kekal berkeyakinan dan berketerampilan menarik by Noor Afiza, Mohd Asmi

“…PEKAN, 22 November 2024 – Seramai 18 orang mahasiswa daripada teras kebudayaan Kelab Teater Senandika dan Kelab Tarian Kencana Pawana Universiti Malaysia Pahang Al-Sultan Abdullah (UMPSA) menghadiri Bengkel Make Up, Program Skill for Life yang dianjurkan oleh Jabatan Belia dan Sukan Negeri Pahang serta Pejabat Belia dan Sukan Daerah Pekan dengan kerjasama Pejabat Kemajuan Masyarakat KEMAS Daerah Pekan.…”
Get full text

The effects of online social interactions on life satisfaction of older Chinese adults: new insights based on a longitudinal approach by Zhou, Dong, Xu, Yi, Ai, Pengya

Subjects: Get full text

Impact of negative life events, self-esteem and social support on engagement in risky behaviors in adolescents : a longitudinal study. by Kwok, Kar Boon., Chow, Cai Wen., Tan, Li Hui., Ho, Li Jun.

“…The current study examined the relationship between stressful life events, self-esteem, social support and engagement in risky behaviors in Canadian adolescents. …”
Get full text

Large range sizes link fast life histories with high species richness across wet tropical tree floras by Baker, TR, Adu-Bredu, S, Affum-Baffoe, K, Aiba, S, Akite, P, Alexiades, M, Almeida, E, de Oliveira, EA, Davila, EA, Amani, C, Andrade, A, Aragao, L, Araujo-Murakami, A, Arets, E, Arroyo, L, Ashton, P, Ifo, SAA, Aymard, GAC, Baisie, M, Balee, W, Balinga, M, Banin, LF, Banki, O, Baraloto, C, Malhi, Y, Moore, S

“…Lineages with higher mortality rates—faster life-history strategies—have larger ranges in all biogeographic settings and have higher mean species-level range sizes in Amazonia. …”

Loneliness, self-efficacy, academic achievement, life satisfaction and depression among Iranian undergraduates at a Malaysian Private University by Molooki, Mahshid

“…The main objective of this study is to investigate the relationship between personal background, family background, loneliness, self-efficacy, academic achievement, life satisfaction and depression among Iranian undergraduates in Malaysia. …”
Get full text

A novel artificial neural network approach for residual life estimation of paper insulation in oil-immersed power transformers. by Nezami, Md. Manzar, Equbal, Md. Danish, Ansari, Md. Fahim, A. Alotaibi, Majed, Malik, Hasmat, Márquez, Fausto Pedro García, Hossaini, Mohammad Asef

“…Results are validated against literature-based life models, establishing a precise input–output correlation. …”
Get full text

Nanofiltration-like forward osmosis membranes with graphene oxide modified polymer-blended subtrate for aerobically-treated palm oil mill effluent treatment / by Wan Nur Ain Shuhada Abdullah, 1994-, author 655804, Lau, Woei Jye, 1983-, supervisor 483710, Farhana Aziz, supervisor 638316, Fakulti Kejuruteraan Kimia Dan Kejuruteraan Tenaga 599090

Nanofiltration-like forward osmosis membranes with graphene oxide modified polymer-blended subtrate for aerobically-treated palm oil mill effluent treatment / by Wan Nur Ain Shuhada Abdullah, 1994-, author 655804

Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…After the first dose, limited antigen availability in germinal centers (GCs) results in a response dominated by B cells that target immunodominant epitopes that are mutated in an Omicron-like variant. After the second dose, these memory cells expand and differentiate into plasma cells that secrete antibodies that are thus ineffective for such variants. …”
Get full text

Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth by Pollock, K, Cheeseman, H, McFarlane, L, Day, S, Tolazzi, M, Turner, H, Joypooranachandran, J, Shramko, K, Dispinseri, S, Mundsperger, P, Bontjer, I, Lemm, N-M, Coelho, S, Tanaka, M, Cole, T, Korber, B, Katinger, D, Ward, A, Scarlatti, G, Sanders, R, Sattentau, Q, Shattock, R

“…<p><strong>Background:</strong> We report findings from an experimental medicine study of rationally designed prefusion stabilised native-like HIV envelope glycoprotein (Env) immunogens, representative of global circulating strains, delivered by sequential intramuscular injection.…”

Flexible liquid crystal displays by Sai Hein Latt Than.

Get full text

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Ferrari, AJ, Santomauro, DF, Aali, A, Lacey, BWH, Rodriguez, JAB

“…<p><b>Methods</b></p> The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. …”

Shelf life evaluation of formulated cookies from Hanjeli (Coix lacryma-jobi L.) and Moringa leaf flour (Moringa oleifera) by Iwansyah, Ade Chandra, Melanie, Dwi, Cahyadi, Wisnu, Indrianingsih, Anastasia Wheni, Khasanah, Yuniar, Indriati, Ashri, Hazrulrizawati, Abd Hamid, Izzah Hayati, Yahya

“…Hanjeli cookies were measured for nutritional composition and shelf life assessment. The shelf life evaluation of hanjeli-moringa cookies was calculated using two approaches, which were accelerated shelf life testing (ASLT) methods with critical moisture content and the Arrhenius method. …”
Get full text
Get full text