Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Results We confirm that only ACK2 inhibits SCF binding fully and prevents HSC proliferation in vitro. …”
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Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell] by He, Zuxing

“…The effect of optimizing crude extract was more important than optimizing the binding buffer. In elution stage, the effect of imidazole was more important than acetic acid. …”
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Structure and protein recognition of G-quadruplexes by Ngo, Khac Huy

“…G-rich oligonucleotides can adopt non-canonical secondary structures called G-quadruplexes (G4s) which are biologically relevant and found in applications and nanotechnology. …”
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The Mark of Cain: The crime of terrorism in times of armed conflict as interpreted by the Court of Appeal of England and Wales in R v. Mohammed Gul by Coco, A

“…On 22 February 2012, the Court of Appeal of England and Wales was called on to interpret the definition of the crime of terrorism as contained in relevant United Kingdom (UK) legislation. …”

Investigation of fluorescence lifetime imaging for quantitative cervical cancer screening and diagnosis by Gu, Jun

“…In addition, analyzing only the top-half of the cervical epithelium shortens the calculation time. …”
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Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Compounds of a global anti-COVID-19 effort called the “Moonshot project” targeting the main protease of SARS-CoV-2 were also screened and promising compounds were progressed further to produce a specific direct-acting SARS-CoV-2 antiviral compound. …”

YAP-DKK1 axis restricts regeneration to the isthmus of the human gastric glands by Zagami, C

“…</p> <p>The human stomach is organised into epithelial invaginations called gastric glands. While tissue damage can trigger regeneration at the gland base, in healthy conditions, stem cell activity is restricted to an anatomical niche called the isthmus. …”

Investigating cofactor transfer for a B₁₂-dependent enzyme by Duong, Alexander T.

“…MCM relies on two other proteins, a G-protein metallochaperone called methylmalonic aciduria type A protein (MMAA) and a protein called adenosyltransferase (ATR), to load and off-load cofactor. …”
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Co-translational integration of the light harvesting complex II and its associated pigments into polymeric membranes by Zapf, Thomas

“…Fluorescence measurements of purified proteopolymersomes indicate successful binding of pigments to the proteins within this new environment. …”
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo... by Liu, Fang

“…Generally, Gram-negative bacterial pathogens have additional outer membranes mainly composed of highly conserved and unique lipopolysaccharide (LPS) molecules, which serve as permeability barriers to prevent the cell bodies from toxic antimicrobial molecules1-2 including many photosensitizers, which have been successfully used in photoinactivation of Gram-positive strains.3-4 Furthermore, LPS, a potent inducer to human innate immune systems, hence called endotoxin, is now primarily responsible for sepsis associated with the infections of Gram-negative pethogens.5-6 Therefore, the most promising strategy is use of LPS neutralizing peptide as the binding ligand to deliver antibacterial agents meanwhile minimize the side effects.7 The first objective of the research in part I is the design and synthesis of photosensitizer-peptide conjugates for multivalent targeted cellular imaging and photodynamic inactivation (PDI) against Gram-negative bacterial strains. …”
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An epigenetic analysis of planarian stem cells by Dattani, A

“…<p>Planarian flatworms possess somatic pluripotent stem cells, called neoblasts (NBs), which are able to differentiate into all cell types that constitute the adult body plan. …”

Beyond Color: Lattice Gauge Theory for Strongly-Coupled Physics by Oare, Patrick R.

“…It is the interaction that yields the strong nuclear force that binds protons and neutrons together. The underlying mathematical picture of QCD is known exactly: it is an 𝑆𝑈(3) gauge theory coupled to six flavors of fermions (the quarks). …”
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The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

“…We demonstrate that the C-terminal portion of PA0285 encompassing the GGDEF and EAL domains binds GTP and c-di-GMP, respectively, but only exhibits PDE activity in vitro. …”
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The structure of hadrons and other potential phases of QCD by Schindler, Stella T.

“…Quantum chromodynamics (QCD) is a mathematical theory describing subatomic particles called quarks and gluons, and the strong force that binds them together into protons and neutrons. …”
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Characterisation of Topoisomerase 1-cleavage complex repair by Lascaux, P

“…As part of its enzymatic activity, TOP1 covalently binds to DNA, creating an intermediate known as TOP1 cleavage complex (TOP1cc) and a single strand DNA break which allows DNA to unwind. …”

Structure and interaction of telomeric and telomerase RNA G-quadruplexes. by Martadinata, Herry.

“…G-rich oligonucleotides are able to form four-stranded nucleic acid structures called G-quadruplexes in cationic solution. These structures are composed of multiple tetrad planes, in which each tetrad plane consists of four guanines that are Hoogsteen base-paired to one another. …”
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