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121
Modeling the Impact of Electrolyte Flow on Heat Management in a Li-Ion Convection Cell
Published 2024“…We show, through physics-based electrothermal modeling and dimensional analysis of a single, planar LIB cell, that electrolyte convection can simultaneously draw heat from the cell and suppress heat generation from entropy change, charge-transfer, and ohmic losses, and that the cell temperature rise can be effectively mitigated when heat removal matches or exceeds heat generation. …”
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122
Non-targeted metabolomics revealing the effects of bisphenol analogues on human liver cancer cells
Published 2022“…Overall, BPs altered metabolites which are associated with energy metabolism, oxidative stress, cell proliferation and nucleotides synthesis. The primary dysregulated pathways included energy and nucleotides synthesis related Purine and Glycolysis/Gluconeogenesis metabolism. …”
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Journal Article -
123
Understanding the disease mechanisms of cerebellar ataxia through induced pluripotent stem cell models
Published 2018“…Finally, to determine the developmental changes in Purkinje cells, human Purkinje cells were generated from control and SCA14 iPSCs using a novel simplified protocol. …”
Thesis -
124
Techniques for analysis and integration of histology data and agent-based modelling of T cell-tumour interactions
Published 2023“…<p>Cytotoxic (CD8+) T cells form an important part of the adaptive immune response. …”
Thesis -
125
Thermal induced coupling of cell adhesion/deadhesion and migration under HBV replication and EGCG treatment
Published 2011“…In the first part of my thesis, TRP was applied as a model system for elucidating the effect of HBV replication on the biophysical responses of HepG2 cells transfected by wild type HBV genome. Moreover, mutant HBV genome is designed to assess the specific activity of the SH3-binding domain of HBx during HBV replication. …”
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Thesis -
126
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis
Published 2024“…In addition, we find an expansion of YeiH-specific CD8 T cells in the blood of axSpA and B27AAU over healthy controls, whereas influenza-specific CD8 T cells were equivalent across groups. …”
Journal article -
127
Sygyzium claviflorum fruit extract preadipocyte differentiation inhibition in 3T3-L1 cells
Published 2024“…Moreover, SCFE suppressed sterol regulatory element binding protein-1 (SREBP-1), peroxisome proliferator-activated receptor-gamma (PPAR-γ), and CCAAT/enhancer-binding protein-alpha (C/EBP-α) gene expressions during preadipocyte differentiation into adipocytes. …”
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128
B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination
Published 2022“…B cells are important in immunity to both severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and vaccination, but B cell receptor (BCR) repertoire development in these contexts has not been compared. …”
Journal article -
129
Evaluating the ecotoxicity of agropesticides and environmental water contaminants using cell-line and zebrafish embryonic assays
Published 2023“…The results showed that the pesticides tested exhibited acute lethality and sublethal effects on the model organisms tested, albeit some to a lesser extent than previously reported findings on single active compounds. Our findings also revealed challenges in using a single broad-spectrum solid-phase extraction method to retain pesticide analytes due to their chemical complexity. …”
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Final Year Project (FYP) -
130
Analysis of hepatocyte antigen presentation and T cell/hepatocyte interaction in the context of hepatitis B virus Infection.
Published 2010“…This study aimed to analyze strategies employed by HBV to evade host’s cellular immune response, which requires an interaction of T cell receptor (TCR) and major histocompatibility complex class I (MHC I)/peptide complex for T cell activation. …”
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Final Year Project (FYP) -
131
Characterization of progesterone receptor isoform-selective activities of progesterone receptor modulators in breast cancer cells.
Published 2008“…This study reveals the effects of progesterone receptor modulators (PRMs) mediated by PR isoforms in PR-transfected MDA-MB-231 cells. Through PR-A and PR-B, PRMs CP8668, AED and Dex-Mes exhibited progesterone agonist effect in which they induced cell spreading, focal adhesion, cell migration and inhibited cell cycle progression. …”
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Thesis -
132
A cross-scale framework for evaluating flexibility values of battery and fuel cell electric vehicles
Published 2024“…This article analyzed and compared the flexibility values of battery electric vehicles and fuel cell electric vehicles for planning and operating interdependent electricity and hydrogen supply chains while considering battery degradation costs. …”
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133
Elucidating the size-dependency of in vitro digested polystyrene microplastics on human intestinal cells health and function
Published 2022“…Interestingly, it is found that the 0.1 µm PS-MPs can perturb redox homeostasis in NCM460 but not in Caco-2 cells. Based on the in vitro experimental boundaries and findings, it is concluded that ingested PS-MPs pose little acute cytotoxic harm to human gastrointestinal health.…”
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Journal Article -
134
Critical analysis of the role of biodegradable polymeric scaffolds in differentiation of human embryonic stem cell into cardiomyocytes
Published 2010“…Owing to the shortage of donors there has been a constant quest to find alternatives to organ transplant. Cell replacement therapy is a promising approach for the treatment of cardiac diseases, but is challenged by a limited supply of appropriate cells. …”
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Thesis -
135
Preparation and characterization of photo electrochemical cells based on nanostructured ZnO and multiwalled carbon nanotubes
Published 2010“…The synthesis of the PEC cell with glass/FtO as base is done using Chemical Bath Deposition Technique. …”
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Final Year Project (FYP) -
136
The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy
Published 2017“…We therefore sought to find a conclusive answer to the question of whether Aβ affects cell plasma membrane fluidity. …”
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Thesis -
137
Cathodoluminescence of self-organized heterogeneous phases in multidimensional perovskite thin films
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Journal Article -
138
Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework
Published 2019“…Our findings revealed that 3D hybrid scaffold enhances cell proliferation and induces cancer cells to undergo EMT, as demonstrated by significant up-regulation of EMT associated transcriptional factors including Snail1, Zeb1, and Twist2; and mesenchymal markers whereas epithelial marker, E-Cadherin was downregulated. …”
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Journal Article -
139
A novel method for segmenting growth of cells in sheared endothelial culture reveals the secretion of an anti-inflammatory mediator
Published 2018“…In one paradigm, endothelial cells are cultured in devices that produce spatially varying shear stress profiles, and the local profile is compared with the properties of cells at the same position. …”
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Journal Article -
140
In vitro and in silico studies of Lawsone on inflammation-induced skin cells for development of skin anti-inflammatory treatment
Published 2024“…In silico works predicted lawsone’s ability to bind to TNF-α with good binding affinity without disruption to the protein’s structure stability.Lawsone is proven to be safe towards non-pathological cells. …”
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