21W.730-2 Expository Writing - Food for Thought: Writing and Reading about Food and Culture, Fall 2005 by Boiko, Karen

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Macrobrachium rosenbergii De Man nodavirus recombinant capsid protein production and its interactions with RNA by Goh, Zee Hong

“…In 2012 the major farming areas in Malaysia were found to be infected by MrNv but till now information on the Malaysian isolate MrNv is still unavailable in the NCBI database and studies of this newly emerged member of the Nodaviridae family were not in depth. …”
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Unconventional split aptamers cleaved at functionally essential sites preserve biorecognition capability by Wang, Ruoyu, Zhang, Qiansen, Zhang, Yi, Shi, Hanchang, Nguyen, Kim Truc, Zhou, Xiaohong

“…An allosteric binding mechanism of BPSPAs, in which a new binding pocket is formed upon the target binding, is revealed by all-atom microsecond-scale molecular dynamics simulations. …”
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Legal translation and ISO standards : a case study by See, Tingting

“…There was no standardized quality assessment for legal translations till April 2020, when the International Organization for Standardization (ISO) published ISO 20771:2020. …”
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Structure and protein recognition of G-quadruplexes by Ngo, Khac Huy

“…Due to the high structural polymorphism, it is still a challenge to specifically target different G4 structures. …”
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The study of radiotherapy resistance of hypoxic tumour for improving survival of cancer patient. by Goh, Yeek Teck.

“…Despite the advent of many new targeted cancer therapies, radiotherapy is still considered an important treatment modality in killing localised cancer cells. …”
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Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function by Liu, Y, Kretz, CA, Maeder, ML, Richter, CE, Tsao, P, Vo, AH, Huarng, MC, Rode, T, Hu, Z, Mehra, R, Olson, ST, Joung, JK, Shavit, JA

“…Genetic predisposition to thrombosis is still poorly understood, and we hypothesize that there are many additional risk alleles and modifying factors remaining to be discovered. …”

Identification of potent new brain cancer EGFR inhibitor from usimine A and usimine B: computer-aided drug design perspective by Roney, Miah, Issahaku, Abdul Rashid, Wilhelm, Anke, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…Brain cancer ranks 10th among cancer-related causes of death for patients worldwide. Medical chemists still have many challenges because of the high side effects, increasing tumor resistance, and low selectivity of new chemotherapeutic medications despite the enormous effort put out to extract, develop, and synthesize them. …”
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Surface composition dependent ligand effect in tuning the activity of nickel–copper bimetallic electrocatalysts toward hydrogen evolution in alkaline by Wei, Chao, Sun, Yuanmiao, Scherer, Günther G., Fisher, Adrian C., Sherburne, Matthew, Ager, Joel W., Xu, Zhichuan Jason

“…Unfortunately, the principles that governs alkaline HER performance remain unclear and are still under debate. By studying the alkaline HER at a series of NiCu bimetallic surfaces, where the electronic structure is modulated by ligand effect, we demonstrate that alkaline HER activity can be correlated with either the calculated or the experimental-measured d band center (an indicator of hydrogen binding energy) via a volcano-type relationship. …”
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Fabrication and characterization of hybrid perovskite thin films for solar cell application by Dayal, Akhilesh

“…The aim of this project is to examine ligands presence and chemical binding on perovskite surface using infrared spectroscopy. …”
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Identification of alternative-splicing events in human monocyte differentiation by Sim, Donald Yuhui

“…The data obtained from RNA-seq still required verification through traditional methods, such as RT-PCR. …”
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Surface modified polymers for controlled macroscopic functions by Chng, S

“…In particular, drug delivery properties were investigated using hole-plate bioassays and HPLC-MS methods, and it was found that the antibiotic, Penicillin V, was still active after being loaded onto the polymer scaffolds, with surface modified polymers binding and releasing more drug than the corresponding controls. …”

Structural study of ribosome : 1) structural basis of EF-G in translocation. 2) molecular mechanism of ribosome-dependent toxin YoeB in mRNA cleavage by Chen, Yun

“…Binding with the ribosome and the GTP analogue facilitate the stabilization of EF-G switch I region, resulting in an ordered model of the active site. …”
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Supported Lipid Bilayer Platform To Test Inhibitors of the Membrane Attack Complex: Insights into Biomacromolecular Assembly and Regulation by Yorulmaz, Saziye, Jackman, Joshua Alexander, Hunziker, Walter, Cho, Nam-Joon

“…On the other hand, clusterin directly interacts with C5b-7 such that C5b-7 is still able to bind to the lipid bilayer, and clusterin affects the subsequent binding of other complement proteins involved in the MAC assembly. …”
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Engineering modular platforms for rapid vaccine development by Brune, K

“…Successfully decorating VLPs is still a major challenge. Genetic fusion or chemical modification is often time-consuming and can lead to misassembly or misfolding, which obstructs generation of the desired immune response. …”

Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…The MS2-MCP system is used to insert into mRNAs of interest special structures to which RNA-binding proteins, fused to a fluorescent protein such as GFP, can then bind. …”

Room-temperature continuous-wave vertical-cavity surface-emitting lasers based on 2D layered organic–inorganic hybrid perovskites by Zhang, Hongbo, Hu, Yuzhong, Wen, Wen, Du, Bowen, Wu, Lishu, Chen, Yu, Feng, Shun, Zou, Chenji, Shang, Jingzhi, Fan, Hong Jin, Yu, Ting

“…Two-dimensional (2D) layered lead halide perovskites with large exciton binding energies, efficient radiative recombination, and outstanding environmental stability are regarded as supreme candidates for realizing highly compact and ultralow threshold lasers. …”
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Synthesis, antimalarial activity, and molecular dynamic approaches of salophen metal complexes by Ali, Amatul Hamizah, Mukhtar, Nur Hafizah, Ling, Ng Yee, Norazmi, Nur Aqilah Zahirah, Agustar, Hani Kartini, Ling, Lau Yee, Abd Karim, Nurul Huda, Yusoff, Siti Fairus Mohd, Borzehandani, Mostafa Yousefzadeh, Hassan, Nurul Izzaty

“…Malaria is still one of the main infectious diseases in tropical climates. …”
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Genotype-specific expression and NLR repertoire contribute to phenotypic resistance diversity in Plantago lanceolata by Safdari, Pezhman, Höckerstedt, Layla, Brosche, Mikael, Salojärvi, Jarkko, Laine, Anna-Liisa

“…Molecular processes contributing to this variation in nature are still poorly known, although theory predicts resistance to evolve at specific loci driven by pathogen-imposed selection. …”
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Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling by Martin Perez, E

“…Importantly, the mechanisms underlying hepatic insulin signalling are still not completely understood.</p> <p>This project is focused on identifying genes involved in hepatic insulin action and aims at a more detailed molecular understanding of how defects in the signalling pathway may lead to insulin resistance. …”