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1561
Understanding lived experiences of bereaved parents of children with chronic life-threatening Illness : towards a culture-specific and meaning-oriented narrative E-writing interven...
Published 2020“…In Singapore, while deaths among children and youths (age<19) have been steadily declining over the past decade, the number of child deaths caused by chronic conditions has increased by about 27% from 120 in 2014 to 152 in 2016. …”
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Thesis-Doctor of Philosophy -
1562
Profiling the growth conditions and persistent organic pollutants (POPS) tolerance of Phenoliferia glacialis USM-PSY62
Published 2024“…USM-PSY62 is a psychrophilic yeast isolated from the ice brine of Antarctica. …”
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Article -
1563
Molecular, Genetic, and Process Approaches for Improving Secreted Pharmaceutical Protein Quality in Komagataella phaffii
Published 2024“…We further showed the comparability between yeast- and CHO-secreted products, providing a framework for rapid product development with this unconventional yeast. …”
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Thesis -
1564
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs
Published 2024“…During the COVID-19 pandemic in Qatar, many patients who were severely ill were colonized and infected by Candida auris, an invasive multidrug-resistant yeast pathogen that spreads through nosocomial transmission within healthcare facilities. …”
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Journal Article -
1565
Identifying the interaction between N-WASP, an actin nucleation factor and vinculin, a focal adhesion protein
Published 2015“…Although the two-hybrid assay showed interaction between N-WASP and vinculin in yeast cells, vinculin could not be detected in the pull down. …”
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Final Year Project (FYP) -
1566
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1567
Tsewang Norbu NGB
Published 2025“…</p><p> </p><p>Before the Chinese invasion of the mid-twentieth century, numerous hand-written manuscript editions were preserved with reverence in monasteries throughout Tibet, as living embodiments of the rNying ma pa tantric dharma; sadly, it may be that none have survived the destructions following the invasion and the subsequent Cultural Revolution.3 Amazingly, however, the wood-blocks for the single xylograph printed edition of the collection (originally made in sDe dge in the late eighteenth century) did survive, and this edition is now being widely reprinted in Tibet.4</p> <p>With the exception of the sDe dge xylograph from East Tibet, all other currently available editions of the rNying ma'i rgyud 'bum, including the Rig 'dzin Tshe dbang nor bu edition, seem to derive from the Himalayan and Southern Tibetan border areas. …”
Dataset -
1568
Screening of microbial population in Sabah tea kombucha pellicle for its potential as prebiotic and probiotic supplement
Published 2024“…This research aimed to determine and analyze the microbial population in kombucha pellicles derived from Sabah black tea, specifically focusing on bacteria and yeast, to gain insights into their abundance, diversity, and potential as prebiotic and probiotic supplements. …”
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Article -
1569
Analysis of behaviour of rhabdomyosarcoma cells under electrical stimulation
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Thesis -
1570
Development and evaluation of a loop-mediated isothermal amplification (LAMP) method for Candida glabrata detection
Published 2024“…The “gold standard” culture method for yeast detection, has low sensitivity with severe consequences, increasing morbidity and mortality rates. …”
Article -
1571
Genetic relatedness of Candida strains isolated from women with vaginal candidiasis in Malaysia
Published 2003“…Six yeast species were detected: Candida albicans, Candida glabrata, Candida lusitaniae, Candida famata, Candida krusei and Candida parapsilosis. …”
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1572
Exploring microbial diversity in green honey from Pulau Banggi Sabah: a preliminary study
Published 2024“…Molds were only detected in raw green honey, while osmophilic yeast counts were higher in raw green honey (16000 ± 0.03 cfu/g) compared to processed green honey (120 ± 0.02 cfu/g). …”
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Article -
1573
Roles of the actin cytoskeleton in structuring the cortical endoplasmic reticulum.
Published 2011“…This rearrangement is thought to be dependent on actin cytoskeleton in yeast. The actin cytoskeleton consists of three structures: actin cables, actin patches and actomyosin rings. …”
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Thesis -
1574
Optimization of carbon and nitrogen sources for phytase production by Mitsuokella jalaludinii, a new rumen bacterial species
Published 2002“…Methods and Results: Replacement of glucose, cellobiose and starch in MF1 medium by RB or palm kernel cake and replacement of trypticase peptone and yeast extract in the medium by SM or enzymatic digested soybean milk significantly increased the phytase production by M. jalaludinii. …”
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Article -
1575
Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity
Published 2020“…In addition, studies in yeast found HMGA2 to prevent the formation of a potentially topologically driven, pathological fork structure, thereby preventing fork collapse and hinting at a possible mechanism of fork protection. …”
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Thesis-Doctor of Philosophy -
1576
Use of co-cultivation method to stimulate the production of antimicrobial natural products from mangrove microorganisms
Published 2015“…Cryptic gene clusters from actinomycetes are suspected to harbor potential in producing bioactive products, and in this study, co-cultivation is utilized to stimulate these cryptic gene clusters in novel antibiotics production. 10 actinomycete strains isolated from Sungei Buloh Wetland Reserve were co-cultured with Mycobacterium Abscessus and Asperigillus Westerdijikiae in two liquid mediums, Glucose-Yeast extract-Malt extract (GYM) and Minimum Media (MM). …”
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Final Year Project (FYP) -
1577
Structural basis of RNA binding by leucine zipper GCN4
Published 2013“…To support further mechanistic studies, herein, we elucidated RNA binding interface of the GCN4 leucine zipper motif from yeast. Solution NMR experiments showed that the LZ-RNA interaction interface is located in the first two heptads of LZ moiety, and that only the dimeric (coiled coil) LZ conformation is capable of binding RNA. …”
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Journal Article -
1578
A regulatory role for repeated decoy transcription factor binding sites in target gene expression
Published 2024“…Using a synthetic system in budding yeast, we demonstrate that repeated decoy sites inhibit gene expression by sequestering a transcriptional activator and converting the graded dose–response of target promoters to a sharper, sigmoidal‐like response. …”
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Article -
1579
Characterization of the near native conformational states of the SAM domain of Ste11 protein by NMR spectroscopy
Published 2016“…SAM domain of the Ste11 protein of budding yeast plays important roles in mitogen-activated protein kinase cascades. …”
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Journal Article -
1580
Discovery of stabilized functional mutants of human aquaporin 1
Published 2016“…A cell-based freeze-thaw functionality assay that was developed by the lab was conducted on yeast Saccharomyces cerevisiae cells transformed with the plasmids to identify the functional mutants, i.e., mutants that express the mutated AQP1 protein that would allow them to exhibit a protective effect in response to rapid freezing. ~ 5% of mutants from a total of 2816 screened from thirty-three 96-well plates were identified after a series of initial and verification screens. …”
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Final Year Project (FYP)