Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex by Diao, X, Shang, Q, Guo, M, Huang, Y, Zhang, M, Chen, X, Liang, Y, Sun, X, Zhou, F, Zhuang, J, Liu, S, Vogel, CFA, Rastinejad, F, Wu, D

“…Crystal structures of the AHR-ARNT-DNA complexes, bound with each of six established AHR ligands, including Tapinarof, 6-formylindolo[3,2-b]carbazole (FICZ), benzo[a]pyrene (BaP), β-naphthoflavone (BNF), Indigo and Indirubin, reveal an unconventional mode of subunit assembly with intimate association between the PAS-B domains of AHR and ARNT. AHR’s PAS-B domain utilizes eight conserved residues whose dynamic rearrangements account for the ability to bind to ligands through hydrophobic and π-π interactions. …”

Modelling and analysis of lubricated piston skirt-cylinder sub-systems in internal combustion engines by Amirun Rasyid Abu Bakar

“…Dynamic viscosities of 0.01Pas – 0.04Pas was considered as they overlapped with the engine oils available are tested. …”
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The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

“…This suggests the N-terminal transmembrane and PAS domains influence the PDE activity in vivo, through modulating the protein conformation.…”
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Molecular, Genetic, and Process Approaches for Improving Secreted Pharmaceutical Protein Quality in Komagataella phaffii by Yang, Yuchen

“…We further showed the comparability between yeast- and CHO-secreted products, providing a framework for rapid product development with this unconventional yeast. …”
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Is Malaysia ready for an islamist prime minister? by Farish A. Noor

“…The call PAS members for their party leader to Prime Minister should the Pakatan Rakyat coalition win power at the next general election raises two questions: will it erode non-Malay support for the opposition coalition and will it change Malaysia's foreign policy?…”
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Ultrasound discrimination between placenta accreta spectrum and urinary bladder varices by Theophilus, KA-B, Collins, S, Nieto-Calvache, A

“…Differentiating between placenta accreta spectrum (PAS) and urinary bladder varices can be difficult on prenatal US because the 2 conditions have similar appearances. …”

Identifying the interaction between N-WASP, an actin nucleation factor and vinculin, a focal adhesion protein by Ganaesh

“…Although the two-hybrid assay showed interaction between N-WASP and vinculin in yeast cells, vinculin could not be detected in the pull down. …”
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Malaysia's 13th general election : prospects and challenges for DAP by Farish A. Noor

“…How will the DAP fare at the coming general election if it has to make compromises with its coalition partners, including the Islamic party PAS that still upholds its vision of eventually creating an Islamikc state in Malaysia.…”
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Dernier état de la jurisprudence sur les clauses attributives de juridiction asymétriques 1 (Civ. 1re, 28 sept. 2022, no 21-13.686, inédit, D. 2023. 1812, obs. L. d’Avout, S. Boll... by Marshall, B

“…Une clause attributive de juridiction qui permet, en cas de litige, à une partie à un contrat d’agir devant « toute autorité compétente » par référence aux règles de compétence de droit commun d’un pays étranger, mais qui contraint l’autre à agir devant des tribunaux désignés de ce pays n’est pas contraire à l’objectif de prévisibilité de l’article 23 de la convention de Lugano du 30 octobre 2007, les juridictions éventuellement amenées à se saisir d’un litige étant identifiable…”

Screening of microbial population in Sabah tea kombucha pellicle for its potential as prebiotic and probiotic supplement by Nasir, Nurul Farhana, Mohamad, Nurul Elyani, Yew, Chee Wei, Saallah, Suryani, Alitheen, Noorjahan Banu

“…This research aimed to determine and analyze the microbial population in kombucha pellicles derived from Sabah black tea, specifically focusing on bacteria and yeast, to gain insights into their abundance, diversity, and potential as prebiotic and probiotic supplements. …”
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Analysis of behaviour of rhabdomyosarcoma cells under electrical stimulation by Ying Ying Woh Kham

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Catalysis and regulation of cyclic dinucleotide specific phosphodiesterases by Rao, Feng

“…In addition, we discovered that the DHH domain-containing protein YybT is an efficient c-di-AMP-specific PDE. The PAS domain of YybT was unexpectedly found to bind them and regulate the PDE activity in response to them or nitric oxide. …”
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Genetic relatedness of Candida strains isolated from women with vaginal candidiasis in Malaysia by Chong, Pei Pei, Lee, Yee Lean, Tan, Boon Chong, Ng, Kee Peng

“…Six yeast species were detected: Candida albicans, Candida glabrata, Candida lusitaniae, Candida famata, Candida krusei and Candida parapsilosis. …”

Exploring microbial diversity in green honey from Pulau Banggi Sabah: a preliminary study by Rajindran, Nanthini, Abdul Wahab, Roswanira, Nurul Huda, Nurul Huda, Oyewusi, Habeebat Adekilekun, Ida Bagus Wayan Gunam, Ida Bagus Wayan Gunam, Mohd. Shariff, Amir Husni, Ismail, Norjihada Izzah, Huyop, Fahrul

“…Molds were only detected in raw green honey, while osmophilic yeast counts were higher in raw green honey (16000 ± 0.03 cfu/g) compared to processed green honey (120 ± 0.02 cfu/g). …”
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Diauxic lags explain unexpected coexistence in multi‐resource environments by Bloxham, Blox, Lee, Hyunseok, Gore, Jeff

“…We establish a tradeoff between Aci2’s fast growth and Pa’s short lags as their mechanism for coexistence. …”
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Roles of the actin cytoskeleton in structuring the cortical endoplasmic reticulum. by Huang, Daniel Wenwei.

“…This rearrangement is thought to be dependent on actin cytoskeleton in yeast. The actin cytoskeleton consists of three structures: actin cables, actin patches and actomyosin rings. …”
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Development and evaluation of a loop-mediated isothermal amplification (LAMP) method for Candida glabrata detection by Yahaya, H., Cheah, Y.K., Chee, H.Y., Than, L.T.L.

“…The “gold standard” culture method for yeast detection, has low sensitivity with severe consequences, increasing morbidity and mortality rates. …”

Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity by Syed Moiz Ahmed

“…In addition, studies in yeast found HMGA2 to prevent the formation of a potentially topologically driven, pathological fork structure, thereby preventing fork collapse and hinting at a possible mechanism of fork protection. …”
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Use of co-cultivation method to stimulate the production of antimicrobial natural products from mangrove microorganisms by Tan, Jin Wei

“…Cryptic gene clusters from actinomycetes are suspected to harbor potential in producing bioactive products, and in this study, co-cultivation is utilized to stimulate these cryptic gene clusters in novel antibiotics production. 10 actinomycete strains isolated from Sungei Buloh Wetland Reserve were co-cultured with Mycobacterium Abscessus and Asperigillus Westerdijikiae in two liquid mediums, Glucose-Yeast extract-Malt extract (GYM) and Minimum Media (MM). …”
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Structural basis of RNA binding by leucine zipper GCN4 by Nikolaev, Yaroslav, Pervushin, Konstantin

“…To support further mechanistic studies, herein, we elucidated RNA binding interface of the GCN4 leucine zipper motif from yeast. Solution NMR experiments showed that the LZ-RNA interaction interface is located in the first two heptads of LZ moiety, and that only the dimeric (coiled coil) LZ conformation is capable of binding RNA. …”
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