Veterinary extension services in the integration program of cattle farming and oil palm in Target Area Concentration (TAC) by Man, Norsida, Siaw, Shin Yee, Yusuf, Munifah Siti Amira, Azizah, Siti

“…Malaysia has 22.2% self-sufficiency, 5.6kg large ruminant meat consumption per capita, and 78.1% import dependency. …”
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Supported Lipid Bilayer Platform To Test Inhibitors of the Membrane Attack Complex: Insights into Biomacromolecular Assembly and Regulation by Yorulmaz, Saziye, Jackman, Joshua Alexander, Hunziker, Walter, Cho, Nam-Joon

“…The findings indicate that vitronectin inhibits membrane association of C5b-7 via a direct interaction with C5b-7 and via competitive membrane association onto the supported lipid bilayer. …”
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Inhibitory Potential of the Truncated Isoforms on Glutamate Transporter Oligomerization Identified by Computational Analysis of Gene-Centric Isoform Maps by Karagöl, Alper, Karagöl, Taner, Li, Mengke, Zhang, Shuguang

“…Conclusion Our computational studies on glutamate transporters offer insights into the roles of alternative splicing on protein interactions and identifies potential drug targets for physiological or pathological processes.…”
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Metformin degradation with combined Ozone/UV/H2O2 process by Fujinami, Shoko Carissa

“…Metformin is a commonly used drug to treat Type 2 diabetic patients. As the number of diabetic patients globally has increased from 108 million in 1980 to 422 million in 2014, it can be seen that diabetes is a common form of illness and in Singapore, there is about 1 in 10 people suffering from diabetes (Lai, 2015). …”
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Hybrid, nanoscale phospholipid/block copolymer vesicles by Lim, Seng Koon, Hoog, Hans-Peter de, Nallani, Madhavan, Bo, Liedberg, Parikh, Atul N.

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Medical management pathways for Cushing’s disease in pituitary tumors centers of excellence (PTCOEs) by Giustina, A, Uygur, MM, Frara, S, Barkan, A, Biermasz, NR, Chanson, P, Freda, P, Gadelha, M, Haberbosch, L, Kaiser, UB, Lamberts, S, Laws, E, Nachtigall, LB, Popovic, V, Schilbach, K, Lely, AJVD, Wass, JAH, Melmed, S, Casanueva, FF

“…Ketoconazole was the most frequently used drug, with a median rate of usage of 26.5% (5-66.7) of those receiving medical therapy. …”

Crystal structure of the FK506 binding domain of plasmodium falciparum FKBP35 in complex with FK506 by Kotaka, Masayo, Ye, Hong, Alag, Reema, Hu, Guangan, Bozdech, Zbynek, Preiser, Peter Rainer, Yoon, Ho Sup, Lescar, Julien

“…The emergence of multi-drug-resistant strains of Plasmodium parasites has prompted the search for alternative therapeutic strategies for combating malaria. …”
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HIV decision support : from molecule to man by Sloot, Peter M. A., Coveney, P. V., Muller, V., Boucher, Charles A. B., Ertaylan, Gokhan, Bubak, Marian

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Water quality and prevalence of extended spectrum beta lactamase producing escherichia coli (ESBL E. coli) in Sungai Terengganu, Malaysia by Noor Haza Fazlin Hashim, Muhammad Azroie Mohamed Yusoff, Rachel Trevor Gunggang, Roslina Abdul Razak, Muhamad Zulfatihi Jaafar, Nasehir Khan E.M. Yahaya

“…From 40 presumptive ESBL isolates tested, 87.5% (35 isolates) were positive for ESBL and carried additional drug resistance genes, including mcr-1, tetW, sul-1, and sul-2. …”
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Experiences, perceptions and ethical considerations of the malaria infection study in Thailand by Naemiratch, B, Kulpijit, N, Ruangkajorn, S, Day, NPJ, Prachumsri, J, Cheah, PY

“…However, due to cross-border movements over the past 5 years, reported malaria cases in Thailand have risen. …”

Synthesis, α-glucosidase inhibition, α-amylase inhibition, and molecular docking studies of 3,3-di(indolyl)indolin-2-ones by Santoso, Mardi, Ong, Li Lin, Aijijiyah, Nur Pasca, Wati, First Ambar, Azminah, Azminah, Annuur, Rose Malina, Fadlan, Arif, Judeh, Zaher M. A.

“…The synthesized 3,3-di(indolyl)indolin-2-ones 1a-p showed desired higher α-glucosidase inhibitory activities and lower α-amylase inhibitory activities than standard drug acarbose. Particularly, compound 1i showed favorable higher α-glucosidase % inhibition of 67 ± 13 and lower α-amylase % inhibition of 51 ± 4 in comparison to acarbose with % inhibition activities of 19 ± 5 and 90 ± 2, respectively. …”
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Combatting pathogenic bacteria with synthetic immunotherapeutics from chitosan: antibody recruiting at engineered bacterial surface with peptidoglycan analogs by Xu, Yuan, Song, Shihao, Duan, Hongwei, Deng, Yinyue, Liu, Xue-Wei

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Factors associated with hepatitis B and C co-Infection among HIV-infected patients in Singapore, 2006 – 2017 by Choy, Chiaw Yee, Ang, Li Wei, Ng, Oon Tek, Leo, Yee Sin, Wong, Chen Seong

“…The majority (86.3%) of HIV-infected patients were mono-infected, while 7.2% were co-infected with HBV, 6.0% with HCV, and 0.5% were co-infected with both HBV and HCV. The most common HCV genotype was GT1 (63%). …”
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Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6 by Zhang, Xiulin, He, Yang, Zhang, Xiaolu, Fu, Bo, Song, Zidai, Wang, Liang, Fu, Rui, Lu, Xuancheng, Xing, Jin, Lv, Jianyi, Guo, Meng, Huo, Xueyun, Liu, Xin, Lu, Jing, Du, Xiaoyan

“…Promising results suggest that TLR6 may be a potential candidate immunotherapy drug for H. pylori infection.…”
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Topical and transdermal botanical formulations of the Chinese pharmacopoeia—a review by Gu, Jingyi, Lane, Majella E., Sil dos Santos, Bruno, Heinrich, Michael

“…The use of botanical materials in TCM formulations is guided by the “Jun‐Chen‐Zuo‐Shi” principle rooted in Yin‐Yang and the five elements' theories. In the ChP 2020, 155 botanical drugs, along with 40 excipients (from the “procedure” section, focusing on processing and technical parameters), were identified from 34 botanical formulations intended for topical/transdermal application. …”
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Development of an app for a thermoelectric cooler system by Ng, Alex Boon Chye

“…Furthermore, the incorporation of TECs into medical equipment, such as temperature-controlled drug delivery systems and portable cooling devices, emphasises their importance in healthcare. …”
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Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro by Zhu, X

“…These findings will not only contribute to the understanding of the mechanisms by which SPRTN proteolysis in DPCs repair, but also provide a powerful <em>in vitro</em> approach for drug screening to develop new cancer treatment strategies.…”

Techniques for analysis and integration of histology data and agent-based modelling of T cell-tumour interactions by Stephens, R

“…We then undertake an exploratory analysis of histology data from a Phase I clinical trial of Simlukafusp (FAP-IL2v), a cancer immunotherapy developed by Roche. …”

Enhanced expression of codon optimized interferon gamma in CHO cells by Yusufi, Faraaz N. K., Yang, Yuansheng, Lee, Dong-Yup, Chung, Bevan Kai-Sheng, Mariati

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‘On-demand’ soft tissue adhesives by Mogal, Vishal Tukaram

“…Various plasma parameters were investigated for controlling model drug release and soft-tissue adhesion of polyester thin films. …”
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