Preparation, motion study and application of autonomous micro and nano devices by Maric, Tijana

“…Micro- and nanomachines are a new generation of nanotechnology, allowing nano- and micro-objects to propel themselves, perform autonomous motion and other on demand actions, such as drug delivery or environmental remediation. …”
Get full text

Image classification of unlabeled malaria parasites in red blood cells by Zhang, Zheng

“…However, this approach will allow observations of malaria parasite progression and provide statistics on how malaria parasites respond to different drug treatments over time.…”
Get full text

Metformin degradation with combined Ozone/UV/H2O2 process by Fujinami, Shoko Carissa

“…Metformin is a commonly used drug to treat Type 2 diabetic patients. As the number of diabetic patients globally has increased from 108 million in 1980 to 422 million in 2014, it can be seen that diabetes is a common form of illness and in Singapore, there is about 1 in 10 people suffering from diabetes (Lai, 2015). …”
Get full text

Efficacy and safety of tirzepatide for treatment of overweight or obesity. A systematic review and meta-analysis by Tan, Bryan, Pan, Xin-Hui, Chew, Jocelyn Han Shi, Goh, Rachel Sze Jen, Lin, Chaoxing, Anand, Vickram Vijay, Lee, Ethan Cheng Zhe, Chan, Kai En, Kong, Gwyneth, Ong, Christen En Ya, Chung, Charlotte Hui, Young, Dan Yock, Chan, Mark Y., Khoo, Chin Meng, Mehta, Anurag, Muthiah, Mark Dhinesh, Noureddin, Mazen, Ng, Cheng Han, Chew, Nicholas W. S., Chin, Yip Han

Get full text

Clinical sub-phenotypes of Staphylococcus aureus bacteraemia by Swets, MC, Bakk, Z, Westgeest, AC, Berry, K, Cooper, G, Sim, W, Lee, RS, Gan, TY, Donlon, W, Besu, A, Heppenstall, E, Tysall, L, Dewar, S, de Boer, M, Fowler, VG, Dockrell, DH, Thwaites, GE, Pujol, M, Pallarès, N, Tebé, C, Carratalà, J, Szubert, A, Groeneveld, GH, Russell, CD

“…The ability to identify sub-groups of patients with shared traits (sub-phenotypes) is an unmet need that could allow patient stratification for clinical management and research. …”

Techniques for analysis and integration of histology data and agent-based modelling of T cell-tumour interactions by Stephens, R

“…Agent-based models (ABMs) allow the simulation of complex biological systems with detailed temporal and spatial resolution. …”

Polymeric nanoparticles and organic fluorophores for cancer sensing and therapy by Ang, Chung Yen

“…With this, we have presented the synthesis and application of a polymer based nanoparticles for drug delivery application. We have extended this work to the in-vivo system and the nano formulation showed a positive effect on the tumor bearing nude mice. …”
Get full text

Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro,... by Yang, Z, Sheehan, AM, Messer, AE, Tsui, S, Sparrow, A, Redwood, C, Kren, V, Gould, IR, Marston, SB

“…Further molecular dynamics simulations could define the specific properties needed for recoupling and allow for the prediction and design of potential new drugs.…”

Advancements in Management Science: Applications to Online Retail, Healthcare, and Non-Profit Fundraising by Zhai, Chen Wen (Sabrina)

“…Previous work on this topic have adopted a classical online learning setup, where the retailer begins the selling horizon with no information about the problem and gains all knowledge about the demand function from the online selling phase. …”
Get full text

3D electron microscopy for analyzing nanoparticles in the tumor endothelium by Mladjenovic, Stefan M., Chandok, Ishaan S., Darbandi, Ali, Nguyen, Luan N. M., Stordy, Benjamin, Zhen, Mei, Chan, Warren C. W.

“…This technique may provide unique insights into the interactions between medical agents, drug carriers, emerging materials, and cells at the single-nanoparticle level throughout tissues.…”
Get full text

Structural and functional studies of C-nucleoside formation enzymes by Li, W

“…The substitution of C-C glycosidic bonds holds the promise of preserving the drug properties of the parent compound while rendering the compound essentially undegradable.…”

Dopamine Nation : Finding Balance in the Age of Indulgence / by Lembke, Anna, Dr., author 655980, Penguin Publishing Group (Online service) 655981

“…Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. …”
Get full text

Resistant hypertension and mortality: an observational cohort study by de la Sierra, A, Ruilope, LM, Staplin, N, Gorostidi, M, Vinyoles, E, Segura, J, Armario, P, Oliveras, A, Williams, B

“…<p><strong>Methods</strong></p> We selected 8146 patients with controlled hypertension (office BP &lt;140/90 mm Hg while being treated with ≤3 antihypertensive drugs) and 8577 with resistant hypertension (BP ≥140 or ≥90 mm Hg while being treated with ≥3 drugs). …”

Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications by Zhang, Simin

“…Novel targets for the development of antiviral drugs and viral detection reagents are required when facing drug-resistant viral strains, viral pathogens without effective and/or economical treatment, and newly emerging viral pathogens. …”
Get full text

Protein delivery options: how well have we succeeded? by Ng, Xu Wen, Subbu, Venkatraman

“…Of the ten top-selling drugs in 2013, the first three (Humira®, Enbrel®, Remicade®) were all monoclonal antibodies for treating autoimmune diseases; together these three accounted for approximately $28 billion in sales. …”
Get full text
Get full text

Detection of single-nucleotide polymorphisms in Plasmodium falciparum by PCR primer extension and lateral flow immunoassay by Moers, APHA, Hallett, R, Burrow, R, Schallig, HDFH, Sutherland, CJ, van Amerongen, A

“…The resistance of Plasmodium falciparum to some antimalarial drugs is linked to single-nucleotide polymorphisms (SNPs). …”

Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

Get full text
Get full text

建立知识经济时代的竞争优势 = Building the competitive advantage in the knowledge economy : an analysis of the added-value of the intellectual capital of Xian-Janssen from the knowledge manageme... by 李一敏 Li, Yimin

“…"Xian-Janssen Pharmaceutical Ltd", as the No.1 leading pharmaceutical JV in China, is a successful model among all.…”
Get full text

Poisson vector graphics (PVG) by Hou, Fei, Sun, Qian, Fang, Zheng, Liu, Yong-Jin, Hu, Shi-Min, Qin, Hong, Hao, Aimin, He, Ying

“…Within the PVG framework, the users specify color as the Dirichlet boundary condition of diffusion curves and control tone by offsetting the Laplacian of colors, where both controls are simply done by mouse click and slider dragging. PVG distinguishes itself from other diffusion based vector graphics for 3 unique features: 1) explicit separation of colors and tones, which follows the basic drawing principle and eases editing; 2) native support of seamless cloning in the sense that PCs and PRs can automatically fit into the target background; and 3) allowed intersecting primitives (except for DC-DC intersection) so that users can create layers. …”
Get full text

RES.LL-005 D4M: Signal Processing on Databases, Fall 2012 by Kepner, Jeremy

“…Search, social media, ad placement, mapping, tracking, spam filtering, fraud detection, wireless communication, drug discovery, and bioinformatics all attempt to find items of interest in vast quantities of data. …”
Get full text