Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…Various protein scaffolds have been designed to recapitulate the specific recognition of presented antigens with the aim to be exploited both diagnostically (e.g. to visualize cells exposed to infectious agents or cellular transformation) and therapeutically (e.g. for the delivery of drugs to compromised cells). In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
Get full text
Get full text

Collection and analysis on data from Drugs.com by Aw, Teng Teng

“…In this report, Scrapy, is a web scraper, which will be used to extract data from Drugs.com. Scrapy is a framework, done in Python and the outputs will be saved in JSON files. …”
Get full text

Nanosized silica particles for chiral drug separation by Tan, Timothy Thatt Yang.

“…The current work addresses the urgent need of novel stationary phases for rapid enantionseparation, and it complements and supports the projects by the PI in the synthesis and application of nanoparticles for achiral and chiral drug separation. The emphasis of this work lies on nanoparticle synthesis and functionalization. …”
Get full text

Genomic profiling of mycobacterium tuberculosis strains, Myanmar by Aung, Htin Lin, Nyunt, Wint Wint, Fong, Yang, Biggs, Patrick J., Winkworth, Richard C., Lockhart, Peter J., Yeo, Tsin Wen, Hill, Philip C., Cook, Gregory M., Aung, Si Thu

Get full text

Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery by Zhang, Fengying, Ngoc, Nguyen Thi Quynh, Tay, Bao Hui, Mendyk, Aleksander, Shao, Yu-Hsuan, Lau, Raymond

“…SEM images coupled with image analysis software reveal that different surface morphology of the microparticles have different drug adhesion mechanisms. Comparison of ACI results and image analysis of SEM images shows that an increase in the particle surface roughness can increase the fine particle fractions (FPFs) using the rod-covered mannitol microparticles as drug carriers. …”
Get full text
Get full text

Overcoming endurance issue : UAV-enabled communications with proactive caching by Xu, Xiaoli, Zeng, Yong, Guan, Yong Liang, Zhang, Rui

“…Specifically, we focus on content-centric communication systems, where a UAV is dispatched to serve a group of ground nodes (GNs) with random and asynchronous requests for files drawn from a given set. With the proposed scheme, at the beginning of each operation period, the UAV pro-actively transmits the files to a subset of selected GNs that cooperatively cache all the files. …”
Get full text
Get full text

Sawmill: From Logs to Causal Diagnosis of Large Systems by Markakis, Markos, Chen, An Bo, Youngmann, Brit, Gao, Trinity, Zhang, Ziyu, Shahout, Rana, Chen, Peter Baile, Liu, Chunwei, Sabek, Ibrahim, Cafarella, Michael

Get full text

Development of multimedia educational software by Saw, Thant Lwin Tun.

“…While this educational software was developed by using Visual Basic programming, graphical presentations and 3D images were drawn by using Autodesk Revit and were exported to Visual Basic as image files for creation of animations.…”
Get full text

Cloud Spark Cluster to analyse English prescription big data for NHS intelligence by Fernando, Sandra, Sowinski-Mydlarz, Viktor, Virdee, Bal Singh

“…Even though Spark is a complete in-memory framework, although limited with its big data platforms facilities compared to Hadoop, Spark analytics engine with Ha-doop distributed file system gives better throughput than Hadoop alone. …”
Get full text

Linking short-term to long-term convergent tectonics using geodetic observations, geological constraints and numerical simulations by Mallick, Rishav

Get full text

SINGAPORE STANDARD : Specification for clean and green urban farms – Agriculture Incorporating Amendment No. 1 /

Get full text
Get full text

Lifesaver boy by Airyn

Get full text

Delay-and-pay: prolonging pharmaceutical patent protection without paying the ‘price’ by Foss-Solbrekk, K

“…<p>This thesis argues that actors use the patent system as part of a ‘delay-and-pay’ strategy to preserve drug prices for as long as possible by delaying generic/biosimilar market entry – and that they have a significant incentive to do so. …”

Dated by Tan, Ping Hao

Get full text

Dated by Ho, Jia Fen

Get full text

Walking like trees by Lim, Jonathan Yong Ern

Get full text

Trolled by Tao, KaiYuan

Get full text

‘Token’ augmented reality visual effects film by Koh, Iris Xuan En

Get full text

Mechanism of damnacanthal induced apoptosis in CEM-SS cell line by Gopalsamy, Banulata, Saiful Yazan, Latifah, Abdul Hamid, Hisyam

Get full text

Data-Driven Classification of Pharmaceutical and Biotechnology Companies by Xu, Angelina

“…We use fundamental financial data, 10-K filings, and company drug development data to develop this new classification scheme. …”
Get full text