Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations by Bi, Jialin, Wee, JunJie, Liu, Xiang, Qu, Cunquan, Wang, Guanghui, Xia, Kelin

“…The Coronavirus disease 2019 (COVID-19) has affected people's lives and the development of the global economy. …”
Get full text

Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study by Shil, RSK, Seed, A, Franklyn, NE, Sargent, BF, Wood, GK, Huang, Y, Dodd, KC, Lilleker, JB, Pollak, TA, Defres, S, Jenkins, TM, Davies, NWS, Cousins, DA, Zandi, MS, Jackson, TA, Benjamin, LA, Easton, A, Solomon, T, Bradley, JR, Chinnery, PF, Smith, CJ, Nicholson, TR, Carson, A, Thomas, RH

“…Female sex, age > 50 years, and hypertension were associated with worse outcomes, and statins or ACE inhibitors with better outcomes.…”

Immunoprofiling of drug-resistant epilepsy with a focus on glutamic acid decarboxylase 65 antibodies by McGinty, R

“…To try and enhance the CBA, molecular cloning techniques for antigen tagging and cell surface expression for use in a live and non-permeabilised CBA were applied. However, antigen surface expression was unsuccessful.…”

Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host-pathogen interactions in the bat airway epithelium by Chan, Louisa L. Y., Gamage, Akshamal M., Tan, Chee Wah, Tan, Kai Sen, Liu, Jing, Tay, Douglas Jie Wen, Foo, Randy Jee Hiang, Rénia, Laurent, Wang, De Yun, Wang, Lin-Fa

“…However, these ALI-AECs did not support SARS-CoV-2 infection, despite E. spelaea ACE2 receptor being capable of mediating SARS-CoV-2 spike pseudovirus entry. …”
Get full text