Cellular studies on the role of OGFOD1, a 2-oxoglutarate-dependent dioxygenase by Attwood, M

“…A number of cellular phenotypes have been reported following OGFOD1 inactivation, including altered ribosome decoding, activation of translational stress pathways and reduced proliferation. …”

A comparison of sodium-glucose co-transporter 2 inhibitor kidney outcome trial participants with a real-world chronic kidney disease primary care population by Forbes, AK, Hinton, W, Feher, MD, Elson, W, Ordóñez-Mena, JM, Joy, M, Fan, X, Banerjee, D, Cole, NI, Munro, N, Whyte, M, Suckling, RJ, Swift, PA, de Lusignan, S

“…However, there are limited data on the generalizability to those without co-existing type 2 diabetes (T2D), and the representativeness of the Study of Heart and Kidney Protection with Empagliflozin (EMPA-KIDNEY) trial has not been adequately explored. We hypothesized that SGLT2 inhibitor kidney outcome trials are more representative of people with co-existing T2D than those without, and that EMPA-KIDNEY is more representative than previous trials.…”

Patient and healthcare professional perspectives on the Practical Guide to Implementing PROMs in Gender-Affirming Care (PG-PROM-GAC): analysis of open-ended responses from patients... by Kamran, R, Jackman, L, Laws, A, Stepney, M, Harrison, C, Jain, A, Rodrigues, J

“…<p><strong>Importance</strong> Several international calls have been made for evidence-based patient-reported outcome measure (PROM) implementation for gender-affirming care. …”

The molecular determinants of Polycomb-mediated gene repression by Fursova, N

“…Combinatorial activity of DNA-binding transcription factors has been proposed to drive lineage-specific transcriptional programmes. …”

Isolated low temperature heat release from binary blends of iso-octane, n-heptane and ethanol in a spark ignition engine by White, SP, Leach, FCP

“…A recently developed method has been shown to isolate LTHR in SI engine conditions, paving the way for more detailed and sophisticated analyses of LTHR characteristics and chemistry under realistic engine conditions. …”

Investigating the functional and metabolic role of carnitine in the diabetic heart using hyperpolarized MRI by Savic, D

“…L-carnitine levels are decreased in the plasma of diabetic patients and L-carnitine supplementation has been shown to have protective effects. L-carnitine transports fatty acids into the mitochondria allowing for subsequent —-oxidation, but it can also export acetyl-CoA from the mitochondria through acetylcarnitine and thereby relieve PDH-flux.…”

Childlessness and its associated factors among Chinese women: a nationwide population-based study by Han, Q, Dang, J, Wu, Y, Ye, W

“…A total of 10,802 women across mainland China who were (or had been) married were included, of whom 5,885 were of reproductive age (20–49 years) and 4,917 of post-reproductive age (≥ 50 years). …”

Afiksasi verba dalam bahasa Indonesia by Rajeg, GPW, Denistia, K

“…Verbal affixation of Bahasa Indonesia (Indonesian [BI]) has been widely discussed in every Indonesian grammar book and theoretical kinds of literature. …”

Inter-organizational competition in humanitarian governance by Corsini, C

“…Since losing control of the Humanitarian Coordinator appointment process in 2018/19, UNDP has been progressively 'competed out' of the humanitarian sector.…”

Programs to Address Violence for Military Families: a Systematic Review by Dodge, J, Wortham, W, Kale, C, Williamson, V, Ross, A, Maher, S, Kononowech, J, Winters, J, Sullivan, K

“…Though a number of these programs exist, to our knowledge, there has been no systematic effort to describe and evaluate these interventions. …”

Incidence, prevalence, and survival of lung cancer in the United Kingdom from 2000–2021: a population-based cohort study by Corby, G, Barclay, NL, Tan, EH, Burn, E, Delmestri, A, Duarte-Salles, T, Golozar, A, Man, WY, Tietzova, I, Prieto-Alhambra, D, Newby, D

“…In the United Kingdom (UK), there has been a major reduction in smoking, the leading risk factor for lung cancer. …”

Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia by Cossins, J, Kozma, I, Canzonetta, C, Hawkins, A, Beeson, D, Sepulveda, P, Dong, YY

“…Causative mutations have been identified in over 30 genes, including DOK7, a gene encoding a post-synaptic protein crucial in the formation and stabilization of the neuromuscular junction. …”

Securing reform? Post-election power sharing and security sector reform in Zimbabwe, Kenya, and Togo, 2006-2013 by Noyes, A

“…Traditionally used to end high-intensity civil wars, recently power sharing has increasingly been used to terminate an array of lower-intensity conflicts, such as election-related violence in Togo in 2006 and Kenya and Zimbabwe in 2008. …”

Strain rate, temperature, and their coupled effects on the deformation process of four polycarbonates and a short glass fibre reinforced polycarbonate composite by Song, P

“…<p>Polycarbonate is a typical glassy thermoplastic polymer, which has been widely used in engineering applications because of its ductility, transparency and impact resistance. …”

Outbreaks of COVID-19 in a tuberculosis treatment sanatorium on the Thailand-Myanmar border: a retrospective cohort analysis by Aung, HKK, Swe, LL, Saito, M, Lesseps, S, Janurian, N, Tun, WPP, Maung Maung, B, Than, A, Watthanaworawit, W, Kaewphanderm, N, Gornsawun, G, Pyae Phyo, A, Nosten, F

“…<p><strong>Background</strong><br> Tuberculosis (TB) is a chronic condition, with overlapping symptoms to those of coronavirus disease 2019 (COVID-19). There has been inconsistent evidence on whether TB is a predisposing factor for developing severe COVID-19. …”

Social inclusion in the legal profession: a study of the solicitor apprenticeship by Polding, E

“…In addition, as participating apprentices were often school leavers rather than graduates, there were few expectations in relation to professional experience that might have been expected of more conventional trainee solicitor recruits. …”

Towards understanding genome regulation via high-resolution analysis of chromatin accessibility by Dai, L

“…<p>Next generation sequencing has been used to in functional genomics to rep- resent specific aspects of chromatin structure, DNA-protein interactions and the epigenome, enriching the knowledge of the non-coding genome which plays significantly roles in gene regulation but is vaguely understood. …”

Determining the feasibility of a full-scale randomised controlled trial evaluating rehabilitation for people after acute patellar dislocation by Forde, C

“…This suggests that the low retention may have been for reasons other than the outcome measurement instruments and follow-up methods used.…”

The COVID guidelines India project: a rapid living evidence synthesis during a pandemic in a LMIC setting by Singh, B, Alexander, H, Tharyan, P, Mathew, JL, Covid Management Guidelines India Group, Garner, P, Rupali, P, Core Committee, Rupali, P, Ryan, H, Steering Committee, Methodology Committee, External Advisory Panel, Expert Working Group – Antiviral, Expert Working Group – Anti-inflammatory, Expert Working Group - Antibody, Expert Working Group - Anticoagulation, Expert Working Group - Respiratory support, Expert Working Group - Other Supportive Therapy, Evidence Synthesis Team, Dissemination Team

“…</p> <br> <p><strong>Results:</strong> Since May 2021, a total of 20 guidelines have been developed spanning pharmacological, respiratory and other supportive interventions for management of COVID-19, with over 83,600 unique page views up to December 2023. …”

Sensitive detection of PIK3CA Exon 20 H1047R breast cancer based on lowcost intercalary dye SYBR Green I real-time qPCR assay by Desriani, Azamris, Rustamadji, Primariadewi, Abna, Inherni Marti, Ibadurrahman, Irsyad, Fuad, Asrul Muhammad, Nurdiani, Dini, Yuliawati, Yuliawati, Herawati, Neng, Fitria, Najmiatul, Warisman, Muhammad Ali, Utami, Nuruliawaty

“…Detection of PIK3CA/H1047R mutation has also been reported for molecular diagnosis and therapeutic application. …”
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