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7521
Identification of potent new brain cancer EGFR inhibitor from usimine A and usimine B: computer-aided drug design perspective
Published 2024“…The results show that Usimine B has been identified as an inhibitor of brain cancer against EGFR protein. …”
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Article -
7522
Measuring ethical behavior of accounting graduates in Malaysia: Comparison between perceptual statements and vignettes
Published 2024“…The failure of accountants/auditors to uphold positive values and maintain ethical behavior while performing professional services has been widely discussed. Most future accountants in Malaysia are accounting graduates from Malaysian Institute of Accountants (MIA) accredited universities. …”
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7523
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7524
Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation
Published 2024“…Electrical stimulation has also been used to attempt to modulate the gut-brain axis with greater spatial and temporal resolution. …”
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Article -
7525
Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism
Published 2024“…However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as their joint depletion severely impacts cell viability. …”
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7526
Re-evaluating GPT-4’s bar exam performance
Published 2024“…Perhaps the most widely touted of GPT-4’s at-launch, zero-shot capabilities has been its reported 90th-percentile performance on the Uniform Bar Exam. …”
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7527
Multi-Keel Passive Prosthetic Foot Design Optimization Using the Lower Leg Trajectory Error Framework
Published 2024“…Single-keel energy storage and return (ESR) prosthetic feet have recently been developed to provide improved walking benefits at an affordable cost in LMICs. …”
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7528
Development of a Self-Report Measure of Prediction in Daily Life: The Prediction-Related Experiences Questionnaire
Published 2024“…Disruptions to prediction abilities have been proposed to underlie characteristics associated with autism. …”
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7529
Oral Carbon Monoxide Enhances Autophagy Modulation in Prostate, Pancreatic, and Lung Cancers
Published 2024“…However, the clinical efficacy of autophagy inhibitors has been inconsistent. To delineate clinical and epidemiological features associated with autophagy inhibition and a positive oncological clinical response, a retrospective analysis of patients is conducted treated with hydroxychloroquine, a known autophagy inhibitor. …”
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7530
Ketamine can produce oscillatory dynamics by engaging mechanisms dependent on the kinetics of NMDA receptors
Published 2024“…Ketamine’s primary molecular targets and its oscillatory dynamics have been characterized. However, how the actions of ketamine at the subcellular level give rise to the oscillatory dynamics observed at the network level remains unknown. …”
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Article -
7531
Manufacturing mesenchymal stromal cells in a microcarrier-microbioreactor platform can enhance cell yield and quality attributes: case study for acute respiratory distress syndrome
Published 2024“…Mesenchymal stem and stromal cells (MSCs) hold potential to treat a broad range of clinical indications, but clinical translation has been limited to date due in part to challenges with batch-to-batch reproducibility of potential critical quality attributes (pCQAs) that can predict potency/efficacy. …”
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7532
Time-series metagenomics reveals changing protistan ecology of a temperate dimictic lake
Published 2024“…Metagenomic samples have been collected and shotgun sequenced from Lake Mendota for the last 20 years. …”
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7533
Predicted Losses of Sulfur and Selenium in European Soils Using Machine Learning: A 2 Call for Prudent Model Interrogation and Selection
Published 2024“…Reductions in sulfur (S) atmospheric deposition in recent decades have been attributed to S deficiencies in crops. Similarly, global soil selenium (Se) concentrations were predicted to drop, particularly in Europe, due to increases in leaching attributed to increases in aridity. …”
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7534
Insights into Li+ Storage Mechanisms, Kinetics, and Reversibility of Defect-Engineered and Functionalized Multi-Walled Carbon Nanotubes for Enhanced Energy Storage
Published 2024“…To overcome these challenges, multi-walled carbon nanotubes (MWCNTs) have been explored as an alternative, offering Li+ storage within the interplanar space between graphene sheets, along with excellent electrical conductivity, and eco-friendliness. …”
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7535
Development and Characterization of a Novel, Low-Cost Method for Measurement of Volatile Organic Compounds
Published 2024“…While there are several commercially-available LCS that can measure environmental volatile organic compounds (VOCs), an important class of hazardous pollutants, these sensors can only make non-specific “broadband” measurements and have, to date, been underutilized in research. This thesis describes the development, characterization, optimization, and use of a novel low-cost instrument for measuring environmental VOCs. …”
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Thesis -
7536
The Relationship between Linguistic Representations in Biological and Artificial Neural Networks
Published 2024“…The scientific tools for investigating human-unique capacities, such as language, have long been limited. For example, we do not have the option to learn about the neural circuits that support these capabilities by studying simpler systems than the human brain, such as animal models. …”
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Thesis -
7537
Structure and dynamics of magnetic domain walls in multi-sublattice magnetic oxides
Published 2024“…Recently, DMI and even faster DW motion have been observed in thin-film rare-earth iron garnets. …”
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Thesis -
7538
Design and Synthesis of Stimuli-Responsive Polymers with Programmable Cleavability
Published 2024“…The first chapter introduces bottlebrush polymers as nanocarriers for therapeutics, and provides a detailed literature analysis of the synthetic and architectural developments that have been reported for these constructs, as well as outlooks for the future. …”
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Thesis -
7539
Trouble on the Range: When Does a National Park Become a Bison Zoo?
Published 2024“…One of these valleys, Lamar, is a hotspot for bison viewing, but, unbeknownst to many casual tourists, the area has also long-been the center of an intense scientific debate. …”
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Thesis -
7540