Identification of novel interactions between MicroRNAs and pattern-recognition receptor signalling in dentritic cells by Pichulik, T

“…Recent evidence has suggested that PRR signalling regulates the expression of microRNAs (miRNAs), important post-transcriptional regulators of gene expression, which have been shown to fine-tune innate immune responses.</p> <p>This thesis describes the discovery of miR-650, a novel PRR-responsive miRNA that is down regulated in monocyte-derived dendritic cells (DCs) on PRR stimulation. …”

Immune Checkpoint Blockade sensitivity and Progression-Free Survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, R, Tong, O, Taylor, C, Kumar Sharma, P, Verge De Los Aires, A, Mahe, E, Ruffieux, H, Nassiri, I, Middleton, M, Fairfax, B

“…For raw data, please refer to the FASTQ files which have been deposited in the European Genome–phenome Archive, which is hosted by the European Bioinformatics Institute and the Centre for Genomic Regulation (accession no. …”

Indicators of global climate change 2022: annual update of large-scale indicators of the state of the climate system and human influence by Forster, PM, Smith, CJ, Walsh, T, Lamb, WF, Lamboll, R, Hauser, M, Ribes, A, Rosen, D, Gillett, N, Palmer, MD, Rogelj, J, von Schuckmann, K, Seneviratne, SI, Trewin, B, Zhang, X, Allen, M, Andrew, R, Birt, A, Borger, A, Boyer, T, Broersma, JA, Cheng, L, Dentener, F, Friedlingstein, P, Gutiérrez, JM, Gütschow, J, Hall, B, Ishii, M, Jenkins, S, Lan, X, Lee, J-Y, Morice, C, Kadow, C, Kennedy, J, Killick, R, Minx, JC, Naik, V, Peters, GP, Pirani, A, Pongratz, J, Schleussner, C-F, Szopa, S, Thorne, P, Rohde, R, Rojas Corradi, M, Schumacher, D, Vose, R, Zickfeld, K, Masson-Delmotte, V, Zhai, P

“…Over the 2013&ndash;2022 period, human-induced warming has been increasing at an unprecedented rate of over 0.2&thinsp;^∘C per decade. …”

PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder by Wang, L

“…However, no evidence for DNA replication defects has been found in these patient-derived cells. The aim of this thesis was to determine cellular pathways that are affected by the S228I alteration and to uncover mechanisms by which PCNAS^228I cells tolerate the perturbed PCNA interactions in specific pathways. …”

Adverse health events associated with antipsychotic use: an umbrella review by Chow, RTS

“…Numerous systematic reviews have found evidence for antipsychotics’ adverse effects, but few attempts have been made to assess the robustness of these evidence. …”

Large-scale profiling of antibody reactivity to glycolipids in patients with Guillain-Barré syndrome by Thomma, RCM, Halstead, SK, de Koning, LC, Fehmi, J, Rinaldi, S, IGOS consortium

“…Extensive research into clinical associations of individual anti-ganglioside antibody specificities has been performed. Recent research has highlighted glycolipid complexes, glycolipid combinations that may alter antibody binding, as targets. …”

Optimization of a Luteolin-loaded Tpgs/poloxamer 407 nanomicelle: the effects of copolymers, hydration temperature and duration, and freezing temperature on encapsulation efficienc... by Mod Razif, Muhammad Redza Fahmi, Chan, Siok Yee, Widodo, Riyanto Teguh, Chew, Yik-Ling, Hassan, Masriana, Ahmad Hisham, Shairyzah, Abdul Rahman, Shamima, Ming, Long Chiau, Tan, Ching Siang, Lee, Siew-Keah, Liew, Kai Bin

“…Background: Luteolin is a flavonoid compound that has been widely studied for its various anti-cancer properties and sensitization to multidrug-resistant cells. …”
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In vitro evaluation of oral contraceptives on long-tailed macaque (Macaca fascicularis) primary ovarian cells by Muhammed, Mikail, Tengku Azizan, Tengku Rinalfi Putra, Mohd Noor, Mohd Hezmee, Abu Hassim, Hasliza, Che'Amat, Azlan, Saleh, Annas Bin, Han, Mark Hiew Wen, Ab Latip, Mohd Qayyum

“…Hormonal contraception has been advocated as an alternative population control method for the long-tailed macaque population, which has increased exponentially due to anthropogenic changes and incidental food subsidies from human food waste. …”
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A comprehensive study of laser irradiated hydrothermally synthesized 2D layered heterostructure V2O5(1−x)MoS2(x) (X = 1–5%) nanocomposites for photocatalytic application by Jameel, Muhammad Hasnain, Yasin, Aqeela, Samia, Mayzan, Mohd Zul Hilmi, Roslan, Muhammad Sufi, Esa, Fahmiruddin, Agam, Mohd Arif, Mohd Zaid, Mohd Hafiz, Althubeiti, Khaled, Aljohani, Mohammed

“…It has been studied that both two-dimensional (2D) MoS2 and V2O5, which are classified as transition metal dichalcogenides and transition metal oxides, are good photocatalyst materials. …”
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Lower desorption temperature in CO 2 capture using various magnesium oxide loading on iron(III) oxide by ultrasonic-assisted synthesis: the adsorption-desorption and isotherm studi... by Lahuri, Azizul Hakim, Jaafar, Nur Farhana, Nordin, Norazzizi, Dzakaria, Norliza, Mohd Yusof, Syawal, Samidin, Salma, Sulaiman, Syazreen Nadia, Marliza, Tengku Sharifah

“…This shows that the Fe3+ ion in the Fe2O3 structure has been successfully replaced by a smaller ion radius of Mg2+ and the ion was successfully incorporated into the Fe2O3 as a substitutional atom. …”
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Estrogenic post-menopausal anti-osteoporotic mechanism of Achyranthes aspera L.: Phytochemicals and network pharmacology approaches by Huq, AKM Moyeenul, Stanslas, Johnson, Nizhum, Nisarat, Uddin, Md. Nazim, Maulidiani, Maulidiani, Roney, Miah, Abas, Faridah, Jamal, Jamia Azdina

“…Hormone replacement therapy is used to treat postmenopausal syndrome caused by estrogen deficiency, but it has been linked to an increased risk of breast cancer. …”
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ranscriptome profile and gene expression during different ovarian maturation stages of Macrobrachium rosenbergii (De Man, 1879) by Mardhiyyah, Mohd Pauzi, Zakaria, Muhammad Faiz, Amin-Safwan, Adnan, Nur-Syahirah, Mamat, Sung, Yeong Yik, Ma, Hongyu, Ikhwanuddin, Mhd

“…Despite significant interest in M. rosenbergii, its gene discovery has been at a relatively small scale compared to other genera. …”
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Identification of novel bovine leukocyte antigen alleles and association of BoLA-DRB3.2*020:02:01 with resistance to Theileria orientalis infection in crossbred Kedah-Kelantan catt... by Agina, Onyinyechukwu Ada, Shaari, Mohd Rosly, Md Isa, Nur Mahiza, Ajat, Mokrish, Zamri Saad, Mohd, Hamzah, Hazilawati

“…The bovine leukocyte antigen (BoLA) gene is a significant genetic part of the immune system and has been used as a disease marker in cattle. In this study, we detected Theileria orientalis, T. sinensis, Anaplasma marginale, Anaplasma platys, Candidatus Mycoplasma haemobos and Trypanosoma evansi by PCR amplification and sequencing of the amplicons. …”

School Management System (SPS): factors affecting school effectiveness by Wan Mahmud, Wan Marfazila, Ab.Jalil, Habibah

“…This research was done for four districts which had been chosen at random, according to the states and zones in Peninsular Malaysia including Central Zone (Petaling Perdana district, Selangor), North Zone (North East district, Penang), East Zone (Kota Bahru district, Kelantan) and South district (Johor Bahru district, Johor). …”
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Determination of mosquitoes species diversity and molecular detection of West Nile virus in wild bird habitats in Perak and Selangor, Malaysia by Jafar Ali, Natasha

“…Meanwhile, WNV antibodies and/or RNA have been demonstrated in wild birds, human, wildlife such as macaques and bats; and farm animals such as swine and horse from 2003 until now. …”
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Are all renewable energy sources the same? a comparative analysis of public perceptions and preferences for renewable energy types in Southeast Asian cities by del Barrio Alvarez, Daniel, Wang, Nan, Sugiyama, Masahiro, Numata, Masako, Thuy, Truong Dang, Abd Aziz, Azlina, Palanca-Tan, Rosalina, Ze Ya, Aung, Yusuf, Ariel Anshory, Abd. Ghani, Awang Noor, Castillo, Gem, Siyaranamual, Martin Daniel

“…However, the majority of existing literature in this region has been constrained by a narrow focus on a comparison between fossil and renewable energy. …”
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In vitro cytotoxicity evaluation of green synthesized alumina nanoscales on different mammalian cell lines by Bukar, Alhaji Modu, Abdullah Jesse, Faez Firdaus, Che Abdullah, Che Azurahanim, M. Noordin, Mustapha, Z. Kyari, Modu, Norman, Ashreen, Mohd-Lila, Mohd Azmi

“…To overcome these challenges, in this study, we use a simple, inexpensive, and less toxic one-pot green chemistry approach instead of a chemical method to synthesize alumina nanoparticles (AlNPs) from Carica papaya extract. Nano-alumina has been widely studied due to its remarkable biological and physiochemical properties at nanoscale. …”
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Metatheoretical study of Lijphart's power sharing theory by Mafakheri, Ramin

“…The researcher also in the two last chapters on the findings focused on the internalintellectual factors; in this regard, it was demonstrated that comparative politics, comparative methods, and new institutionalism have been the main influential methodological and theoretical contexts in the construction and development of power sharing theory. …”
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Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells by Foo, Jhi Biau

“…Dillenia suffruticosa has been used traditionally to treat cancerous growth. …”
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Phytochemical analysis and cytotoxic effects of mango (Mangifera indica L) kernel on breast cancer cell lines by Abdullah, Al-Shwyeh Hussah

“…Although numerous study has been done on plants to discover new drugs for the treatment of chronic diseases like cancer, the products of the mango plant species Mangifera indica L. waterlily, particularly the kernel have not adequately investigated. …”
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