Biomolecular hydration in protein-protein interaction, protein stability and aggregation and lead optimization : computational studies by Mohan Rajan Pradhan

“…"JAL‟ provides 3 novel utilities that have not yet been reported in other software packages: (1) computation of residence times of waters which are then used to rapidly identify water bridges involving multiple waters (2) rapid computation of buried waters in an explicit solvent MD trajectory using a novel “evaporation” technique and (3) a structure based search to compute the likelihood of favorably displacing interfacial waters; this method contrasts well with other available sophisticated but computationally expensive free energy methods. …”
Get full text

新加坡英汉双语儿童对形状量词 “条”、“片”、“粒”的习得研究 = A study of the acquisition of Chinese shape classifiers tiao, pian, li by English-Chinese bilingual children in Singapore... by 李婷 Lee, Grace Ting

“…本文研究结果能为新加坡华语教育界提供有价值的参考，并为形状量词的习得研究带来新的发现。 There has been much research on children’s acquisition of shape classifiers (e.g. …”
Get full text

会话分析研究 ： “like” 在新加坡华语中的语用功能 = Conversation analysis : “like” in Singapore Mandarin conversations by 陈珠凤 Tan, Kyu Houng

“…Through the process of the high frequency usage, there have been extensions in discourse functions of “like” aside from its original semantic meaning. …”
Get full text

范晔《后汉书》“论”、“赞”研究 = Study on Lun and Zan of Fan Ye's History of Eastern Han by 关天辰 Guan, Tianchen

“…Among Early Four Historiographies, the value of Fan Ye's History of Eastern Han has always been underestimated due to the fact that he was announced to be a rebel. …”
Get full text
Get full text

Talking careers: using interviews with learner stakeholders to understand the graduate outcome gap. Stakeholder internal report. Autumn 2024. by Conroy, Dom, Poku, Mary-Jane, Patel, Jade, Diop, Leah, Huda, Nahid, Benn, Jade, Olasope, Awesome

“…Given the critical importance for all learners of securing graduate level work, understanding factors relevant to addressing the graduate outcome gap as identified within the experiences and views of key stakeholders, i.e., of learners of colour, have been neglected in the literature to date. This internal report presents exploratory research designed to help address this area of neglect and to contribute to the relevant evidence base. …”
Get full text

Black hole binary formation and mergers in supermassive black hole discs by Rowan, C

“…<p>Following the first gravitational wave (GW) detection in 2015, there have now been 90+ detections of merging black holes (BHs). …”

Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer by Mason, J

“…In CRC, EVs are known to be potent drivers of primary tumour growth and metastasis, and have also been shown to modulate response to treatment by promoting drug resistance. …”

Investigating S-acylation in the metabolic dysfunction of the T2D heart by Dennis, KMJH

“…The lipid post translational modification <em>S</em>-acylation has been linked to regulating CD36 trafficking. However, it remains unknown whether CD36 is <em>S</em>-acylated in the heart and whether CD36 <em>S</em>-acylation levels are altered in T2D.…”

Boronic acid and nitrofuranyl derivatives as potential therapeutics by Dey, AL

“…‘Rule of 5’, there has been extensive research on lead-like compounds other than those in the realm of small molecule drug-likeness. …”

Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…Seroprevalence studies evaluating population prevalence of SARS-CoV-2 antibodies have an important role in understanding the spread of and population vulnerability to SARS-CoV-2 infection. Most have been performed in adults, and those in children have predominantly tested samples obtained opportunistically in a clinical context or in school-based populations, both of which bring potential biases.…”

Production and characterization of collagen and gelatin from edible jellyfish (Acromitus hardenbergi Stiasny, 1934) for fabrication of biofunctional scaffold by Khong, Nicholas Mun Hoe

“…Jellyfish have always been an important fishery commodity and a multi-million business widely practised in China, Japan, Malaysia, Indonesia, Thailand, Vietnam and the Philippines. …”
Get full text

Structure and functions of a metallo-beta-lactamase- like hypothetical protein bleg1_2437 from alkali-tolerant soil bacterium Bacillus lehensis G1 by Tan, Soo Huei

“…In the present study, there are 1202 hypothetical proteins (HPs) have been discovered from newly sequenced genome of alkali-tolerant soil bacterium B. lehensis G1, HP Bleg1_2437 may likely be an MBL. …”
Get full text

Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell] by He, Zuxing

“…However, optimization of efficient purification method of miraculin from miracle fruit has not been reported in the literature. Immobilized metal ion affinity chromatography (IMAC) with nickel-NTA was employed for miraculin purification from the extract of the pulp with optimization. …”
Get full text

Development and validation of questionnaire on knowledge, attitudes, practices and perceived barriers related to nutrition care process among clinical dietitians in Malaysia by Bahari, Zaini

“…To date, no questionnaire has been developed and validated to assess the KAPB on the NCP. …”
Get full text

Antimicrobial susceptibility and molecular profiles of acinetobacter baumannii in Makkah hospitals, and the potential use of bacteriophage as a treatment option by Raees, Fahad

“…There are increasing trends of resistance to agents that been reserved to treat carbapenem-resistant A. baumannii i.e. tigecycline and colistin. …”
Get full text

Factors associated with body weight status and internet addiction among malaysian university students in Penang: mixed method study before and during covid-19 pandemic by Isaac, Nesamalar

“…In this study, it has been demonstrated that severely internet addiction students have inappropriate dietary behaviour and poor diet quality. …”
Get full text

Digestibility of low-cost ingredients in pelleted feed by grass carp (Ctenopharyngodon idella C. et V.) by Law, A.T.

“…In the MARDI feed, the fish meal and soya bean meal were digested most by the fish: the digestion coefficients for protein were 90.81% and 96.21%, respectively; for fat the values were 100% and 98.79%, respectively; and for gross energy the values were 83.37% and 82.71%, respectively. …”
Get full text

Storage and eruption of silicic magma across the transition from dominantly effusive to caldera-forming states at an arc volcano (Santorini, Greece) by Druitt, Timothy H., Fabbro, Gareth N., Costa, Fidel

“…Processes driving crystallization appear to have been similar in the two systems, despite the differences of scale. …”
Get full text
Get full text

Discrete time optimal control and its applications in power systems by Zhang, Hehong

“…A closed-form mathematical derivation for the DTOC algorithm was fi rst proposed by Han, which has been widely used to design estimators, observers and noise-tolerant differentiators. …”
Get full text

Role of N-WASP in cell proliferation : implication for organ development and cancer by Verma, Apoorva

“…Development of organs such as lungs and mammary glands requires elongation and branching of epithelial tissues which are critically depended on apical-basal polarity, cell adhesion, cell proliferation and interactions with the extracellular matrix proteins. N-WASP has also been shown to regulate cell invasion and EMT (Epithelial to Mesenchymal transition), which are often upregulated during cancer progression. …”
Get full text