Identification of novel interactions between MicroRNAs and pattern-recognition receptor signalling in dentritic cells by Pichulik, T

“…Recent evidence has suggested that PRR signalling regulates the expression of microRNAs (miRNAs), important post-transcriptional regulators of gene expression, which have been shown to fine-tune innate immune responses.</p> <p>This thesis describes the discovery of miR-650, a novel PRR-responsive miRNA that is down regulated in monocyte-derived dendritic cells (DCs) on PRR stimulation. …”

Indicators of global climate change 2022: annual update of large-scale indicators of the state of the climate system and human influence by Forster, PM, Smith, CJ, Walsh, T, Lamb, WF, Lamboll, R, Hauser, M, Ribes, A, Rosen, D, Gillett, N, Palmer, MD, Rogelj, J, von Schuckmann, K, Seneviratne, SI, Trewin, B, Zhang, X, Allen, M, Andrew, R, Birt, A, Borger, A, Boyer, T, Broersma, JA, Cheng, L, Dentener, F, Friedlingstein, P, Gutiérrez, JM, Gütschow, J, Hall, B, Ishii, M, Jenkins, S, Lan, X, Lee, J-Y, Morice, C, Kadow, C, Kennedy, J, Killick, R, Minx, JC, Naik, V, Peters, GP, Pirani, A, Pongratz, J, Schleussner, C-F, Szopa, S, Thorne, P, Rohde, R, Rojas Corradi, M, Schumacher, D, Vose, R, Zickfeld, K, Masson-Delmotte, V, Zhai, P

“…Over the 2013&ndash;2022 period, human-induced warming has been increasing at an unprecedented rate of over 0.2&thinsp;^∘C per decade. …”

PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder by Wang, L

“…However, no evidence for DNA replication defects has been found in these patient-derived cells. The aim of this thesis was to determine cellular pathways that are affected by the S228I alteration and to uncover mechanisms by which PCNAS^228I cells tolerate the perturbed PCNA interactions in specific pathways. …”

Adverse health events associated with antipsychotic use: an umbrella review by Chow, RTS

“…Numerous systematic reviews have found evidence for antipsychotics’ adverse effects, but few attempts have been made to assess the robustness of these evidence. …”

Large-scale profiling of antibody reactivity to glycolipids in patients with Guillain-Barré syndrome by Thomma, RCM, Halstead, SK, de Koning, LC, Fehmi, J, Rinaldi, S, IGOS consortium

“…Extensive research into clinical associations of individual anti-ganglioside antibody specificities has been performed. Recent research has highlighted glycolipid complexes, glycolipid combinations that may alter antibody binding, as targets. …”

2DEG enhancement via epilayer stress engineering in AlN/GaN/AlN heterostructure by Patwal, Shashank

“…The AlGaN/GaN high electron mobility transistors (HEMTs) have been extensively studied during this time. The two-dimensional electron gas (2DEG) at the AlGaN/GaN heterointerface can be achieved without doping owing to their polarization properties. …”
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MECHANICS OF MATERIALS by Ferdinand P. Beer, E. Russell Johnston, Jr., John T. Dewolf

PandoraHearts : Caucus Race, by Shinobu Wakamiya, author 655895, Jun Mochizuki, illustrator 655896

“…Within these pages, four fairy tales unfold, each peering into one of the houses of the four great dukedoms: Vessalius, Rainsworth, Barma, and Nightray. …”
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Cosystolic Expansion of Sheaves on Posets with Applications to Good 2-Query Locally Testable Codes and Lifted Codes by First, Uriya A., Kaufman, Tali

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Modeling and Implementation of the U.S. Hydrogen Production Tax Credit by Giovanniello, Michael A.

“…Following the passage of the IRA, there has been a vigorous debate focusing primarily on the time-matching requirements — that is, the period over which electricity use must match production from contracted generators — for grid-connected H2 production to receive the PTC. …”
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Revealing Structural and Spin-state Dependent Reactivity of Single Atom Catalysts (SACs) with Systematically Improvable Computational Tools by Jia, Haojun (贾皓钧)

“…This reactivity is different from what has been observed for large sets of square planar model homogeneous catalysts. …”
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The development and application of mass-spectrometry-based tools to monitor proteome remodeling in microbes by Telusma, Bertina

“…Understanding the balance of these contributions has historically been challenging. As such, there is a need for approaches that can quantitatively resolve the contributions of protein synthesis and protein degradation pathways in a wide array of cellular and environmental contexts. …”
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The Cognitive Underpinnings of Legal Complexity by Martínez, Eric

“…Although principles of communicative efficiency and legal doctrine dictate that laws be comprehensible to the common world, legal documents have long been attested to be incomprehensible to those who are required to comply with them (i.e. everyone). …”
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Shifting Paradigms: Data-Centric Approach for Marine Statics Correction using Symmetric Autoencoding by Kanniah, Brindha

“…The traditional workflow for correcting marine statics has been based on a model-centric paradigm. This paradigm involves a series of transformations between non-commensurate spaces: first, inversion from seismic data space to velocity model space and second, forward modeling from velocity model space to seismic data space. …”
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Investigating Interventions in Fine-grained Contexts for Habit Formation by Khan, Mina

“…Fine-grained specific contexts are commonly used in habit formation, but interventions in automatically-detected fine-grained contexts have rarely been explored for habit formation. We investigate habit-formation using interventions in fine-grained mobile, physical-world and digital, computer-based contexts, making three key contributions for each: a survey to identify behavior change needs, a prototype system designed to deliver fine-grained context-specific interventions, and a study to investigate habit-formation using interventions in fine-grained contexts, compared to interventions in less fine-grained contexts. …”
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Quantum mechanical theory of dynamic nuclear polarization in solid dielectrics by Hu, Kan-Nian, Debelouchina, Galia Tzvetanova, Griffin, Robert Guy, Smith, Albert A.

“…Historically these mechanisms have been discussed theoretically using thermodynamic parameters and average spin interactions. …”
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Effects of electromagnetic field on proliferation, differentiation, and mineralization of MC3T3 cells by Teoh, Swee-Hin, Suryani, Luvita, Too, Jian Hui, Hassanbhai, Ammar Mansoor, Wen, Feng, Lin, Daryl Jimian, Yu, Na

“…Pulsed electromagnetic fields (PEMFs) have been documented to promote bone fracture healing in nonunions and to enhance the maturation of osteoblastic cell, which is the key element in bone tissues. …”
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Contrasting effects of vasculogenic induction upon biaxial bioreactor stimulation of mesenchymal stem cells and endothelial progenitor cells cocultures in three-dimensional scaffol... by Chan, Jerry Kok Yen, Liu, Yuchun, Teoh, Swee-Hin, Chong, Mark S. K., Yeow, Chen-Hua, Kamm, Roger D., Choolani, Mahesh

“…Clinical translation of bone tissue engineering approaches for fracture repair has been hampered by inadequate vascularization required for maintaining cell survival, skeletal regeneration, and remodeling. …”
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Exploring the utility of silane cross-linkers for synthesis of superhydrophobic antibacterial fabrics by Agrawal, Neha

“…Metal-oxide nanoparticles have been employed to offer antibacterial activity and nanoscale roughness, essential to achieve superhydrophobicity and antibacterial functionality on the fabric. …”
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Liposomal nanotherapy for treatment of atherosclerosis : passive versus active targeting by Darwitan, Anastasia

“…Inflammation is the underlying pathological process of atherosclerosis, the major cause of most CVD, but has not been adequately addressed. Additionally, the increasing age trend of general population will present increasing incidence with individual’s unique and complex coronary anatomy with high-risk comorbidities. …”
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