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A bilayer swellable drug-eluting ureteric stent : localized drug delivery to treat urothelial diseases
Published 2019“…On deployment, the device swells to co-apt with the ureteric wall and ensure drug availability to these tissues. …”
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Journal Article -
2
Layer-by-layer assembled micro and nano carriers for drug delivery applications
Published 2013“…In nano- or microparticulate drug delivery, both control of the drug release and interaction of the particles with the cellular environment are critical attributes. …”
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Thesis -
3
A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence
Published 2018“…The first layer is needed for sustained release of drug while the second layer is required for close contact with urothelial wall. …”
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Thesis -
4
Characterization and evaluation of bilayer coating for enhanced localization and sustained drug delivery for fibrosis-induced ureteral stricture
Published 2016“…The usage of a bilayer coating, consisting of a hydrogel layer and a drug-loaded polymer layer, allows for direct contact with the ureter walls upon swelling and drug delivery through the urothelium. …”
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Final Year Project (FYP) -
5
Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents
Published 2021“…In addition to the emergence of resistance to last resort drugs, bacteria escape antibiotics killing by forming complex biofilms. …”
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Journal Article -
6
Increasing antibiotic activity by rapid bioorthogonal conjugation of drug to resistant bacteria using an upconverted light-activated photocatalyst
Published 2022“…We demonstrate that the mode of action is due to increased inhibition of peptidoglycan cell wall biosynthesis. The findings in this study demonstrate that on-demand NIR-light activated bioorthogonal conjugation of Van to microbes is a viable alternative treatment in combating drug-resistant bacteria.…”
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Journal Article -
7
Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”
Thesis -
8
Investigation of blood pressure regulation schemes
Published 2009“…Hence, continuous monitoring and careful control of the infusion of drug is required. Since the middle 1970s, many researches have been conducted using various types of feedback control system to regulate blood pressure through the infusion of antihypertension drug [5]. …”
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Final Year Project (FYP) -
9
Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens
Published 2024“…To fill the existing gap in drug dose personalization and simplification of complex medication regimens commonly encountered in the treatment of cardiovascular disease, tuberculosis, and tapering of corticosteroid therapy, a modular titratable polypill approach that simultaneously addresses both aspects is proposed. …”
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Article -
10
Methods for the Study of Galactofuranose in Mycobacteria
Published 2024“…Second, we leveraged the rapidly expanding set of biosynthetic probes of the mycobacterial cell wall to rapidly characterize intracellular distances between distinct layers of the cell wall in Mycobacterium tuberculosis model organisms Corynebacterium glutamicum and Mycobacterium smegmatis using fluorescence resonance energy transfer. …”
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Thesis -
11
Information structure of subordinate clauses in Miriwoong
Published 2019“…Finally, paratactic clauses were found to 1) express sequential events or 2) draw a relation between two observations.…”
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Final Year Project (FYP) -
12
Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials
Published 2008“…We intend to fill this gap by interrogating the biophysical events involved in membrane-polymer interaction, biological adhesion, tissue engineering and cellular fluid mechanics. …”
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Research Report -
13
Construction and characterization of a Lactococcus lactis in-trans surface display system harboring murine glycosylated tyrosinase related protein-2
Published 2015“…The Generally Regarded as Safe (GRAS) status of LAB such as Lactococcus lactis coupled with non-recombinant strategy of in-trans surface display system, provide a safe platform for therapeutic drug and vaccine development. However, therapeutic proteins fused with cell-wall anchoring motif production are predominantly limited to prokaryotic expression system. …”
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Thesis -
14
Assessing surface seals of soils on slopes
Published 2017“…Flexible wall falling-head permeability test was used to determine the saturated permeability of the soil in the laboratory. …”
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Final Year Project (FYP) -
15
Wage premium in Singapore.
Published 2010“…In a broader picture, wage-risk premiums could also be used to derive the value of a statistical life, which till today is widely debated and is a highly controversial topic. …”
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Final Year Project (FYP) -
16
Utilizing food waste and thermoplastic starch (TPS) in 3D printed PLA formulations for sustainable and customizable controlled delivery systems
Published 2024“…With the addition of TPS, the drug release profile can be adjusted from 8 – 120 hours using different TPS ratios and different printed wall thicknesses. …”
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Thesis-Master by Research -
17
Thermal effects on particle deposition in microchannels
Published 2016“…Transport and interactions of colloidal particles and biomolecules in microchannels are of great importance to many microfluidic applications, such as drug delivery in life science, microscale heat exchangers in electronic cooling, food processing industry etc. …”
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Thesis -
18
Investigation of phenylpropanoid sucrose esters as antidiabetic compounds
Published 2020“…Since hybrid 77 is a systemic drug, dosing of the compound would have to account for both the rate at which it is transported across the gut wall and its toxicity. …”
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Thesis-Doctor of Philosophy -
19
Shadow connection.
Published 2011“…Through this final year project, I seek to understand the use of the player’s shadow as a game controller and the possible effect of drawing the distance between the player and the game closer, making the player’s realization of the game controller being a crucial existence. …”
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Final Year Project (FYP) -
20
The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films
Published 2013“…The study of the influences of additives on the drug delivery characteristics from PLGA thin films as a coating on angioplasty balloons was reported in this thesis. …”
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Thesis