Transdermal Drug Delivery by Ong, Yuhui

“…As each drugs have different molecular properties, operation parameters are varied accordingly. …”
Get full text

Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…</p> <p>The current COVID-19 pandemic has highlighted the urgent need for vaccines and antiviral drugs. The principal topic of my DPhil centres on addressing these needs for viral infection. …”

Deep learning methods for genome-based prediction of drug resistance in Mycobacterium tuberculosis by Wang, C

“…Recent years have seen a concerning rise in drug-resistant tuberculosis cases, calling for the development of new approaches for drug susceptibility testing. …”

A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria by Chen, Yahua, Yong, Melvin, Li, Ming, Si, Zhangyong, Koh, Chong Hui, Lau, Pearlyn, Chang, Yi Wei, Teo, Jeanette, Chan-Park, Mary B., Gan, Yunn-Hwen

“…The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. …”
Get full text

Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”

Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo... by Liu, Fang

“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
Get full text

End of the line by Chia, Wei Ting

“…My Final Year Project “End of the Line” is an experimental effort to create an expressive piece of game design, writing and drawing to explore the possibilities of creating a narrative driven card game that combines elements of walking simulators, interactive fiction, and strategic card games. …”
Get full text

RES.10-001 Making Science and Engineering Pictures, Fall 2014 by Frankel, Felice C.

Get full text

AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

Get full text

Engineering culture: logics of optimization in music, games, and apps by Morris, JW, Prey, R, Nieborg, DB

“…Through comparative cases of music, games, and apps that draw on trade press and industry discourse, institutional and financial analysis, and select interviews with musicians, we consider various forms of, and strategies for, what we call cultural optimization. …”

The strategy of coercive isolation U.S. security policy by Timonthy W. Crawford

“…From this discussion we also draw several conclusions about the conditions that favour the success of coercive isolation strategies. …”
Get full text
Get full text

‘I don’t care who joins my choir’: investigating attitudes to diversity and inclusivity in lower- and upper-voice choirs in the United Kingdom by MacGregor, E

“…We conclude by making initial recommendations for how choirs might recognise and address such challenges, and call for a shift in the research agenda to pay greater attention to exclusionary factors in amateur and community music participation…”

Antimicrobial efficacy testing of antibiotic-containing biodegradable nanopolymers against biofilm and planktonic cells. by Polimyr Caesar Dave Pelisco Dingal.

“…With efficient use of drug-encapsulated nanopolymers, bactericidal dosages are sufficiently lowered and dosing intervals can be extended due to the sustained drug release feature afforded by these efficacious nanocarriers.…”
Get full text

Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…</p> <br> <p><strong>Funding:</strong> Wellcome Trust, Bill &amp; Melinda Gates Foundation, EU Horizon 2020, and UK National Institute for Health and Care Research.…”

Turning rebellion into money? Social entrepreneurship as the strategic performance of systems change by Teasdale, S, Roy, MJ, Nicholls, A, Hervieux, C

“…</p> <p><strong>Managerial Summary:</strong> Social entrepreneurs often call for systems change to tackle wicked problems such as poverty or climate change. …”

ADVANCING WOMEN LEADERSHIP IN HIGHER EDUCATION / by Lei Mee Thien, Rahimi Che Aman, Muhammad Muftahu

“…Beyond a compilation of insights, this book serves as a call to action. It invites educational policymakers to initiate pragmatic policies, fostering an inclusive environment where women's voices are heard and valued. …”

Buying influence? The international diplomacy behind donor financing of the World Bank’s International Development Association by Xu, J

“…The first is why the hegemon maintained its burden shares regardless of rise or fall in economic status; I call this <em>‘Hegemonic Lag’</em>. The second is why ascending powers were slow to assume greater burden-shares despite economic ascents; I call this <em>‘Challenger Inertia.’…”

Settling velocity of a porous object by Muhammad Khalil Khaidir

“…In actual situations, particles found in wastewater which are commonly called flocs are porous which means that there are cavities within the particles that allow advection flow through it. …”
Get full text

Essays on the market for corporate bonds by Levonmaa, A

“…Using intraday transaction data from the TRACE database, I analyse over 1,000 of the most liquid corporate bonds, a total of 9.5 million trades. Drawing on similar studies of other markets, the relationship between returns and order flow is modelled using a vector autoregression, and the information content of a trade is measured as the long-run price impact of a shock to order flow. …”

CFD analysis of flow across adjacent buildings with concave roof structure using large-eddy simulation (LES) by Foo, Tze Jie

“…The software to be used is an open source CFD program called OpenFoam, which exposes the user to Linux kind of programming environment. …”
Get full text