Simulated bacterial genomes for evaluating SNP calling pipelines by Bush, S

“…This archive is provided as an online supplementary dataset for the Bush, et al. manuscript "Genomic diversity affects the accuracy of bacterial SNP calling pipelines". It contains a set of 254 SNP-containing genomes, VCFs containing nucmer and Parsnp strain-to-representative genome SNP calls, and the final truth sets of SNPs used for evaluation.…”

Factors affecting pre-failure instability of sand under plane-strain conditions by Wanatowski, D., Chu, Jian

“…Experimental data obtained from a plane-strain apparatus are presented in this paper to show that a pre-failure instability in the form of a rapid and sustained increase in strain rate can occur for both contractive and dilative sand under fully drained conditions. …”
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A low-cost, open-source cylindrical Couette rheometer by Erni, Makita, Hart, A. John, Trumper, David, Owens, Crystal E.

“…Here, we introduce a low-cost (under USD$200 bill of materials) Open Source Rheometer (OSR), constructed entirely from thermoplastic 3D printed components and off-the-shelf electromechanical components. …”
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A novel instrumented projectile for investigation of impact dynamics by Pang, Xin

“…This proposed model is based on an exponential stress-strain relation that takes into consideration of the strain-hardening behaviour of the aluminium foam specimens. …”
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Variational models in martensitic phase transformations with applications to steels by Muehlemann, A

“…Bain in 1924 on the optimality of the so-called <em>Bain strain</em>.</p> <p>In Chapter 2, we review the Ball-James model and related concepts. …”

Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth by Pollock, K, Cheeseman, H, McFarlane, L, Day, S, Tolazzi, M, Turner, H, Joypooranachandran, J, Shramko, K, Dispinseri, S, Mundsperger, P, Bontjer, I, Lemm, N-M, Coelho, S, Tanaka, M, Cole, T, Korber, B, Katinger, D, Ward, A, Scarlatti, G, Sanders, R, Sattentau, Q, Shattock, R

“…Structural studies were supported by the Bill and Melinda Gates Foundation (INV-002916).</p>…”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Ferrari, AJ, Santomauro, DF, Aali, A, Lacey, BWH, Rodriguez, JAB

“…Governments and multilateral organisations should prioritise pandemic preparedness planning alongside efforts to reduce the burden of diseases and injuries that will strain resources in the coming decades. <p><b>Funding</b></p> Bill & Melinda Gates Foundation.…”

Why You Should Tap Innovation at Deep-Tech Startups by Raff, Stefan, Murray, Fiona E., Murmann, Martin

“…In today’s business environment, firms must navigate labor shortages, market shifts, geopolitical tensions that strain supply chains and manufacturing, and mandates to adopt sustainable practices. …”
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Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…AMR infections resulted from local transmission of resistant strains. These results form a baseline against which to monitor the impacts of control measures.…”

Description of Paralactobacillus selangorensis gen. nov., sp. nov., a new lactic acid bacterium isolated from chili bo, a Malaysian food ingredient by Leisner, J J, Vancanneyt, M, Goris, J, Christensen, H, Rusul, G

“…This organism, isolated from a Malaysian food ingredient called chili bo, is an obligatory homofermentative, rod-shaped lactic acid bacterium. …”
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Tunable metasurfaces for active nanophotonics by Omar Abdelrahman Mohamed Abdelraouf

“…Metasurfaces consist of small unit cells called meta-atoms, where each meta-atom can impose different light scattering properties based on its dimensions or orientations. …”
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…SATAY is also performed in drug-sensitive strains to examine antifungals that lack activity against conventional laboratory strains. …”

Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo... by Liu, Fang

“…Generally, Gram-negative bacterial pathogens have additional outer membranes mainly composed of highly conserved and unique lipopolysaccharide (LPS) molecules, which serve as permeability barriers to prevent the cell bodies from toxic antimicrobial molecules1-2 including many photosensitizers, which have been successfully used in photoinactivation of Gram-positive strains.3-4 Furthermore, LPS, a potent inducer to human innate immune systems, hence called endotoxin, is now primarily responsible for sepsis associated with the infections of Gram-negative pethogens.5-6 Therefore, the most promising strategy is use of LPS neutralizing peptide as the binding ligand to deliver antibacterial agents meanwhile minimize the side effects.7 The first objective of the research in part I is the design and synthesis of photosensitizer-peptide conjugates for multivalent targeted cellular imaging and photodynamic inactivation (PDI) against Gram-negative bacterial strains. …”
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