Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration by James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard

“…Here we tested the hypothesis that persistent production of these cytokines in the meningeal compartment and diffusion into underlying GM can drive chronic MS-like GM pathology. Lentiviral transfer vectors were injected into the sagittal sulcus of DA rats to deliver continuous expression of TNF + IFNγ transgenes in the meninges and the resulting neuropathology analysed after 1 and 2 months. …”
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Linking personal control and environmental distraction with creative outcome through satisfaction action with work environment and social interaction / by Sanaz Ahmadpoor Samani, 1984-, author 605358

Highly reliable carbon nanotube-based composite fibers cross-linked by a 3D polymer network by Sun, Gengzhi, Zheng, Lianxi, Zhan, Zhaoyao, Jiang, Chunbo, Hansen, Reinack V., Khor, Yengpeng, Pang, John Hock Lye

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Robust perfluorophenylboronic acid-catalyzed stereoselective synthesis of 2,3-unsaturated O-, C-, N- and S-linked glycosides by Tatina, Madhu Babu, Xia, Mengxin, Rao, Peilin, Judeh, Zaher M. A.

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Linking short-term to long-term convergent tectonics using geodetic observations, geological constraints and numerical simulations by Mallick, Rishav

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High-density three-dimensional network of covalently linked nitric oxide donors to achieve antibacterial and antibiofilm surfaces by Wang, Liping, Hou, Zheng, Pranantyo, Dicky, Kang, En-Tang, Chan-Park, Mary B.

“…We have invented a novel pretreatment chemistry for device surfaces to produce a high-density three-dimensional (3-D) network of covalently linked S-nitrosothiol (RSNO), which is a nitric oxide (NO) donor. …”
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Wireless channel modeling and spectrum monitoring for interference mitigation and link reliability insurance for existing and future CBTC systems by Kalyankar Shravan Kumar

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Sig2GRN : a software tool linking signaling pathway with gene regulatory network for dynamic simulation by Zhang, Fan, Liu, Runsheng, Zheng, Jie

“…Background: Linking computational models of signaling pathways to predicted cellular responses such as gene expression regulation is a major challenge in computational systems biology. …”
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Linking microstructure and local mechanical properties in SiC-SiC fiber composite using micromechanical testing by Zayachuk, Y, Karamched, P, Deck, C, Hosemann, P, Armstrong, DEJ

幽禁中之丰姿，落寞中之妖冶：《唐詩名媛集》述評 = Charming in silence and coquettish in desolate : a commentary on Tangshi Mingyuan Ji by 曲景毅 Qu, Jingyi

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Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

“…We show here that colon cancer cell lines express also the paralog APC-like (APCL or APC2). …”
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Phytochemical analysis and cytotoxic effects of mango (Mangifera indica L) kernel on breast cancer cell lines by Abdullah, Al-Shwyeh Hussah

“…Although numerous study has been done on plants to discover new drugs for the treatment of chronic diseases like cancer, the products of the mango plant species Mangifera indica L. waterlily, particularly the kernel have not adequately investigated. …”
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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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Enriching the methanol generation via CO2 photoconversion over the cockscomb-like fibrous silica copper by Mahadi, Bahari, Che Rozid, Mamat, Aishah, Abdul Jalil, Shing, Lo Sook, Nurul Sahida, Hassan, F. F.A., Aziz, Alhassan, Mansur, Mohd Ghazali, Mohd Nawawi, Kamarizan, Kidam, Herma Dina, Setiabudi

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Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors by Luo, Dahai

“…The RIG-I-like receptors (RLRs)—RIG-I, MDA5, and LGP2—detect intracellular pathogenic RNA and elicit an antiviral immune response during viral infection. …”
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Chrysanthemum-like Au@Polydopamine synthesized using one-pot method and its advantage in immunochromatographic assay by Zhang, Gang-gang, Lai, Xiao-cui, Ding, Neng-shui, Xiong, Qirong, Hou, Shuai, Duan, Hongwei, Lai, Wei-hua

“…Flower-like gold nanoparticle (AuNF) is widely used as a probe. …”
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Genes for carnivory : a comparative study on the local duplication of papain-like cysteine proteases in carnivorous plants by Tan, Qiao Wen

“…Thus, the presence of protein degrading enzymes such as papain-like cysteine proteases (PLCPs) in trap fluids is not surprising. …”
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Bio-inspired Flow Sensing and Prediction for Fish-like Undulating Locomotion: A CFD-aided Approach by Zhou, Han, Hu, Tianjiang, Low, Kin Huat, Shen, Lincheng, Ma, Zhaowei, Wang, Guangming, Xu, Haijun

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Local rainfall is more likely than distant thunderstorms to affect movement behaviour in Northern Kenyan elephants by Mulder, T, Mortimer, B, Ferwerda, J, Vollrath, F

“…We conclude that climate change makes a strong case for studying elephant behaviours in response to environmental cues during the day and night, especially in dry-land study sites like Northern Kenya.…”

GOLDEN2-like1 is sufficient but not necessary for chloroplast biogenesis in mesophyll cells of C4 grasses by Lambret-Frotte, J, Smith, G, Langdale, J

“…In land plants, chloroplast biogenesis is regulated by a family of transcription factors named GOLDEN2-like (GLK). In C4 grasses, it has been hypothesized that genome duplication events led to the sub-functionalization of GLK paralogs (GLK1 and GLK2) to control chloroplast biogenesis in two distinct cell types: mesophyll and bundle sheath cells. …”