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4001
The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster
Published 2017“…In the current study, we identified the paralog of the Drosophila tej gene, tapas (tap), which is an ortholog of vertebrate Tdrd7. Like Tej, Tap is localized at the nuage. Alone, tap loss leads to a mild increase in transposon expression and decrease in piRNAs targeting transposons expressed in the germline. …”
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Journal Article -
4002
The magnitude and risk factors of intestinal parasitic infection in relation to human immunodeficiency virus infection and immune status, at ALERT hospital, Addis Ababa, Ethiopia
Published 2015“…Human Immunodeficiency Virus (HIV) and intestinal parasitic infections are among the main health problems in developing countries like Ethiopia. Particularly, co-infections of these diseases would worsen the progression of HIV to Acquired Immunodeficiency Syndrome (AIDS). …”
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Journal Article -
4003
Maternal infections during pregnancy and the risk of childhood leukaemia in the offspring: Evidence from large-scale cohort studies
Published 2021“…In the I4C analysis, maternal urinary tract infection (HR, 1.68; 95% CI, 1.10-2.58) and respiratory tract infection (HR, 1.54; 95% CI, 1.05-2.26) were associated with increased risk of childhood leukaemia. Influenza-like illness showed a similar pattern but with less precise estimates (HR, 1.62; 95% CI, 0.76-3.42). …”
Thesis -
4004
Financial elites and the spatial variation of inequality: examining the intersection of gender, race and class in Frankfurt, London, and New York
Published 2021“…Finally, it seeks to assess the influence of external stakeholders like executive search firms (ESFs) and regulators on the formation and reproduction of financial elites. …”
Thesis -
4005
Development of image-based method for the quantitative assessment of cartilage damage from CT as a biomarker in osteoarthritis
Published 2024“…<p>Preclinical studies, like those for drug development, require quantitative methods to assess osteoarthritis (OA). …”
Thesis -
4006
Metabolic maturation of induced pluripotent stem cells derived cardiomyocytes
Published 2018“…By simultaneously targeting both maturation methods we have shown a degree of maturation through an increased movement towards reduced glycolysis and increased FAO in our iPSC-CMs.</p> <p>Like others this thesis has shown that iPSC-CMs mature slowly over time with changes in structural genes occurring during the first month of differentiation and continuing to increase up to 3 months, whereas metabolic changes took longer to develop. 3D culture on collagen-derived scaffolds and engineered heart tissue (EHT) accelerated this maturation time and increased mitochondrial oxidative metabolism while decreasing anaerobic glycolysis. …”
Thesis -
4007
Molecular characterisation of methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in cats, dogs and pet owners in a Veterinary Hospital
Published 2022“…Having close contact with animals like allowing them to lick face and having other animals had a significant association with carriage of staphylococci in this study. …”
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Thesis -
4008
Impact of BPL penalty functions and PSF models in PET/CT radial spatial resolution recovery
Published 2024“…Advanced reconstruction algorithms like TOF, BPL, and PSF models, along with OSEM have shown spatial resolution enhancements based on the FWHM measured. …”
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Monograph -
4009
HiPIMS deposition of VO2 thermochromic coating for enhanced optical properties
Published 2022“…In chapter 4, a HiPIMS deposition technique for VO2(M) thin film on a commercial material, such as soda-lime glass substrate, was established with a high deposition rate of 5.7 nm/min. The VO2(M) deposited on soda-lime glass exhibits excellent crystallinity and thermochromic properties (highest luminous transmission Tlum ≈ 30.4%, and solar modulation ΔTsol ≈ 12%) in comparison with similarly prepared VO2 on high temperature glass and quartz substrates. …”
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Thesis-Doctor of Philosophy -
4010
Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…Further application of the PS-MS assay to preclinical pharmacokinetic (PK) study found that, the assay was simple and rapid with overall analysis time of 1 min and a full plasma concentration vs. time profile of sunitinib could be obtained from a single mouse. …”
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Thesis -
4011
Antimicrobial activity, phytochemical and toxicity analyses of salam [Syzygium polyanthum (Wight) Walp.] leaf extract and its application in food
Published 2018“…Generally the significant reduction of natural microflora in tested food samples were started at 0.50% (v/v) of extract at 5 min. During storage, 5% (v/v) showed better effect in controlling the microbial survival throughout the storage time. …”
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Thesis -
4012
Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition
Published 2024“…By leveraging targeted and untargeted mass spectrometry (MS) of endogenous tyrosine-phosphorylated proteins, which enables phosphosite-specific quantification of TK signaling networks, I report several cell line-specific vulnerabilities not predicted to exist at the genetic level, and the consensus observation that sustained activity of SRC family kinases (SFKs), or of the SRC-like kinases ABL1/2, is an important contributor to GM-TKI tolerance in all lines. …”
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Thesis -
4013
Fluid-fluid displacement in porous-media microfluidics
Published 2024“…Many questions remain, however, regarding how the macroscopic displacement patterns are controlled by the microscale interactions between the fluid interface and the solid surface in systems under geometric confinement like microfluidic devices and porous media. This fluid-solid interaction—exacerbated by the roughness inherent to all natural and engineered surfaces—introduces a large energy dissipation near the solid boundary that challenges our ability to interpret laboratory experiments and develop mathematical models. …”
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Thesis -
4014
Smart window for tuning transparency and noise absorption
Published 2019“…As a tunable optical surface scatter, it turns transparent with a smooth surface like a flat glass; but it turns ‘opaque’ (translucent) with the micro-rough surface. …”
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Thesis-Doctor of Philosophy -
4015
VR-CFD : interactive simulation of computational fluid dynamics
Published 2020“…The developed VR-CFD application utilized an attractive design with bright colours, familiar game characters and game-like user interface aimed to make the introductory CFD class fun, interactive and engaging, helping students intuitively grasp the physics concepts. …”
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Final Year Project (FYP) -
4016
Phase transitions by an abundant protein in the anammox extracellular matrix mediate cell-to-cell aggregation and biofilm formation
Published 2021“…The Brosi_A1236 structure was computationally predicted to consist of immunoglobulin-like anti-parallel β-strands, and circular dichroism conducted on the isolated surface protein indicated that β-strands are the dominant higher-order structure. …”
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Journal Article -
4017
An NKX2-1GFP and TP63tdTomato dual fluorescent reporter for the investigation of human lung basal cell biology
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Journal Article -
4018
Functional metagenomic analysis of quorum sensing signaling in a nitrifying community
Published 2021Get full text
Journal Article -
4019
High mobility 3D Dirac semimetal (Cd₃As₂) for ultrafast photoactive terahertz photonics
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Journal Article -
4020