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4121
Lithological controls of the Mg isotope composition of the Lena River across seasons and its impact on the annual isotope flux to the Arctic Ocean
Published 2024“…This number coincides with the value of summer baseflow reported in earlier works. Therefore, like in the recently studied Yenisey River basin, the Mg isotope signature of the Lena River water likely stems from a mixture of carbonate (−2.0 ≥ δ<sup>26</sup>Mg ≥ −2.5 ‰) and silicate (0 ≥ δ<sup>26</sup>Mg ≥ −0.2 ‰) rocks in its watershed. …”
Journal article -
4122
Towards formal verification of Bayesian inference in probabilistic programming via guaranteed bounds
Published 2024“…Crucially, these bounds are fully automated and require no user-provided auxiliary information like loop invariants. Thus they can serve as a ground truth to verify and debug approximate inference. …”
Thesis -
4123
The paradoxes of wind power
Published 2009“…Wind is argued by its proponents to be nearly competitive with fossil sources – and fully competitive once environmental externalities like CO2 emissions are taken into account in prices. …”
Journal article -
4124
Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors for new-onset gastric cancer and gastric diseases in patients with type 2 diabetes mellitus: a population-bas...
Published 2024“…<p><strong>Objective: </strong>To compare the risks of gastric cancer and other gastric diseases in patients with type-2 diabetes mellitus (T2DM) exposed to sodium-glucose cotransporter 2 inhibitors (SGLT2I), dipeptidyl peptidase-4 inhibitors (DPP4I) or glucagon-like peptide-1 receptor agonists (GLP1a).</p> <p><strong>Design: </strong>This was a population-based cohort study of prospectively collected data on patients with T2DM prescribed SGLT2I, DPP4I or GLP1a between January 1st 2015 and December 31st 2020 from Hong Kong. …”
Journal article -
4125
Determination of octreotide acetate as radiosensitizer in breast cancer cell lines
Published 2022“…Ionizing radiation (IR), like X-rays and gamma rays, are used for c Cancer treatment because they can penetrate soft tissue, bone vs soft tissue. …”
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Thesis -
4126
Phytochemical analysis and cytotoxic effects of mango (Mangifera indica L) kernel on breast cancer cell lines
Published 2015“…Although numerous study has been done on plants to discover new drugs for the treatment of chronic diseases like cancer, the products of the mango plant species Mangifera indica L. waterlily, particularly the kernel have not adequately investigated. …”
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Thesis -
4127
Biogenic amines and urocanic acid in keropok lekor, and their effects on cytotoxicity and proinflammatory mediator secretion of macrophage cell culture
Published 2017“…Scombroid fish poisoning (SFP) or histamine fish poisoning (HFP) is caused by consumption of mishandled fish or fishery products containing high contents of histamine and leads to allergy-like reaction. Keropok lekor or Malaysian fish sausage is a widely consume fish product. …”
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Thesis -
4128
Inhibition of endoplasmic reticulum stress using 4-phenyl butyrate mitigates osteoporosis in a mouse model of hindlimb suspension
Published 2024“…The tibiae bones of the untreated HLS group demonstrated lower osteocyte density, numerous multinucleated osteoclast-like cells, and adipocyte infiltration within the marrow, while micro-CT revealed lower bone volume fraction, reduced trabecular thickness, along with fewer trabeculae striations with increased trabecular separation. …”
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Thesis -
4129
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes
Published 2022“…We carried out loss- and gain-of-function experiments in MIN6 and EndoC-bH1 cell lines. We analysed previously published mouse andhuman T2D data sets.Results:Bulk RNA-seq revealed thatb-cell dedifferentiation is associated with the induction of genes associated with epithelial-to-mesenchymal transition (EMT) in prediabetic (2-week-old) and diabetic (12-week-old) Tg7 mice. …”
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Journal Article -
4130
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4131
Conformational design characterization of a truncated diamine oxidase
Published 2014“…By maintaining the native protein’s pH profile, the mini protein was highly active at 40 °C and stable at pH 7, with a half-life of 80 min at 50 °C. Results from the kinetic studies showed that the Km value for native diamine oxidase was 0.274 mM and 1.3 mM for the mini protein. …”
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Thesis -
4132
Tropical peat subsidence, nutrient losses and oil palm seedling growth due to different water table depths
Published 2018“…The system was made of exchange chamber of air pump with the flow rate ranges between 1 and 3.5 L min-1, exchange chamber of (2670 mL plastic container) and a trap (250 mL Erlenmeyer flask). …”
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Thesis -
4133
Self-learning shape recognition in medical images
Published 2019“…As training data is often corrupted by many factors like inherent noise/artifacts and non-ideal delineations in this thesis, many efforts have been devoted to developing SSMs that are robust to data corruption. …”
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Thesis -
4134
Nanoscale Origins of Thermal Transport Phenomena for Hybrid Layered Perovskites
Published 2025“…This probe identifies the persistence of bulk-like phonons even in the atomically thin 2D LHPs, in addition to identifying coherent acoustic phonons in lead iodide 2D LHPs potentially capable of carrying thermal energy across the organic-inorganic interfaces without scattering. …”
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Thesis -
4135
Exploring the utility of silane cross-linkers for synthesis of superhydrophobic antibacterial fabrics
Published 2019“…Functionalization of the textiles with additional properties like superhydrophobicity and antibacterial activity can greatly improve their performance, especially in clothing and healthcare sectors. …”
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Thesis -
4136
Postprandial glucose, insulin and incretin responses differ by test meal macronutrient ingestion sequence (pattern study)
Published 2020“…Results: There were significant food intake sequence × time interaction effects on plasma glucose, insulin, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) concentrations (P < 0.001). …”
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Journal Article -
4137
Towards automated damage detection for in-situ remanufacturing
Published 2021“…Remanufacturing is the restoration of used products to a like-new condition, with warranty matching the original product. …”
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Thesis-Doctor of Philosophy -
4138
Sequence- and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analog
Published 2021“…Compared to DNA and RNA, peptide nucleic acids (PNAs) are chemically stable and have a neutral peptide-like backbone, and thus, they show significantly enhanced binding to natural nucleic acids. …”
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Journal Article -
4139
Two-step machine learning enables optimized nanoparticle synthesis
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Journal Article -
4140
A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system
Published 2021“…As proof of principle, we present examples studying various aspects related to hematopoietic cells (T cell development in vivo and activation in vitro, differentiation of macrophages and dendritic cells, as well as a leukemia-like phenotype induced by overexpressing a proto-oncogene). …”
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Journal Article