BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress by Vasudevarao, MD, Posadas Pena, D, Ihle, M, Bongiovanni, C, Maity, P, Geissler, D, Mohammadi, HF, Rall-Scharpf, M, Niemann, J, Mommersteeg, MTM, Redaelli, S, Happ, K, Wu, C, Beisaw, A, Scharffetter-Kochanek, K, D’Uva, G, Malek Mohammadi, M, Wiesmüller, L, Geiger, H, Weidinger, G

“…Pharmacological inhibition of ATM and ATR kinases revealed that DNA damage response signaling is essential for zebrafish heart regeneration. Manipulation of Bone Morphogenetic Protein (BMP)-Smad signaling using transgenics and mutants showed that BMP signaling alleviates cardiomyocyte replication stress. …”

Tropism of subgroup J avian leukosis virus as detected by in situ hybridization by Arshad, S. S., Smith, L. M., Howes, K., Russell, P. H., Venugopal, K., Payne, L. N.

“…Viral gene expression could not be detected in the bone marrow or tumour tissues using this test. Higher levels of viral gene expression in the bursa of Fabricius infected with RAV-1, but not with HPRS-103, might help explain the inability of the latter virus to induce lymphoid leukosis.…”
Get full text

Weak implementation of RSA algorithm by Lim, Si Yi

Get full text

Interactive E-learning environment for learning BJT via simple project by Muhammad `Arif Bin Abdul Malek

Get full text

Potential for consortial relations among special libraries in Singapore. by Chiang, Mei Ling.

Get full text

Entry mode choice of Singapore software firms into the International/Regional markets. by Chung, Susan Lai Ling.

Get full text

ATM broadband network multilevel control by Kan, Siew Leong.

Get full text

Rummage my heart : exploring grief surrounding the passing of a loved one by Ang, Jane Jia Ying

Get full text

Integrated ECG-PCG module for distributed diagnosis and home health care (D2H2) by Kanthimathi Srinivasan Kalyani.

Get full text

Effects of dehydrothermal treatment on collagen by Yeo, Sherrill Yan Ling.

“…Collagen is the most fundamental unit of the extra cellular matrix and is found in most mammal tissues such as the tendon, cartilage, bone and skin. Due to its excellent biocompatibility, collagen is often used as a matrix for cell infiltration in many tissue regenerative applications. …”
Get full text

Synthesis and application of titanium dioxide nanotube and composites by Liang, Kun

“…Two different applications were explored using TiO2 nanotube structures and its composites: bone morphogenetic protein-2 (BMP-2) delivery and photocatalytic for water purification. …”
Get full text

Ontogeny of intestinal intratumoural macrophages and their contribution in cancer regulation by Soncin, Irene

“…In contrast to their LP counterparts, the intratumoural F4/80(hi) macrophages are able to self-renew and lose the bone marrow dependency. Since their depletion via CSF1R blockade diminishes the tumour burden, our data underline the potential of these tumour-promoting intestinal macrophages as an attractive target for successful cancer immunotherapies.…”
Get full text
Get full text

Elucidation of the EP defect in Diamond-Blackfan anemia by characterization and prospective isolation of human EPs by Iskander, D, Psaila, B, Gerrard, G, Chaidos, A, Foong, HE, Harrington, Y, Karnik, LC, Roberts, I, de la Fuente, J, Karadimitris, A

“…By combining flow cytometry, cell-sorting, and single-cell clonogenic assays, we identified Lin(-)CD34(+)CD38(+)CD45RA(-)CD123(-)CD71(+)CD41a(-)CD105(-)CD36(-) bone marrow cells as EEP giving rise to BFU-E, and Lin(-)CD34(+/-)CD38(+)CD45RA(-)CD123(-)CD71(+)CD41a(-)CD105(+)CD36(+) cells as LEP giving rise to CFU-E, in a hierarchical fashion. …”

Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria by Gargiulo, L, Papaioannou, M, Sica, M, Talini, G, Chaidos, A, Richichi, B, Nikolaev, AV, Nativi, C, Layton, M, de la Fuente, J, Roberts, I, Luzzatto, L, Notaro, R, Karadimitris, A

“…The mechanism of bone marrow failure (BMF) in paroxysmal nocturnal hemoglobinuria (PNH) is not yet known. …”

A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling by Deng, H, Zhang, J, Wang, Y, Joshi, D, Pi, X, De Val, S, Schwartz, MA

“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. …”

Information literacy skills of Singapore secondary school students. by Ng, Song Beng.

Get full text

Explaining signals and systems with graphics and animations (II) by Michael Cahyadi Tjondro Kusumo

Get full text

Determinants of R&D activities and performances of firms in Singapore manufacturing sector by Auw, Chor Khoon, Loo, Chin Chye, Woo, Yin Leng

Get full text

Characterization of spatial variation of indoor coverage for HDTV in Singapore (part 1) by Nur Sakinah Ahmad.

Get full text

Implementation of a radar prototype on an unmanned arial vehicle by Liu, Jiaqing

Get full text