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1
Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes
Published 2013“…Various protein scaffolds have been designed to recapitulate the specific recognition of presented antigens with the aim to be exploited both diagnostically (e.g. to visualize cells exposed to infectious agents or cellular transformation) and therapeutically (e.g. for the delivery of drugs to compromised cells). In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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Journal Article -
2
Bad Mexican : portrayal of corruption and the drug trade in Man on Fire, Traffic, and La Ley de Herodes.
Published 2011“…By victimizing the United States and demonizing Mexico, Hollywood films such as Traffic and Man on Fire create stereotypes of Mexicans based on the drug trade and corruption in Mexico so the United States can define its identity and become Mexico’s saviour. …”
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Final Year Project (FYP) -
3
Transdermal Drug Delivery
Published 2016“…As each drugs have different molecular properties, operation parameters are varied accordingly. …”
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Final Year Project (FYP) -
4
Nanosized silica particles for chiral drug separation
Published 2010“…The current work addresses the urgent need of novel stationary phases for rapid enantionseparation, and it complements and supports the projects by the PI in the synthesis and application of nanoparticles for achiral and chiral drug separation. The emphasis of this work lies on nanoparticle synthesis and functionalization. …”
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Research Report -
5
Investigating viral glycosylation pathways for drug and vaccine development
Published 2021“…</p> <p>The current COVID-19 pandemic has highlighted the urgent need for vaccines and antiviral drugs. The principal topic of my DPhil centres on addressing these needs for viral infection. …”
Thesis -
6
‘Token’ augmented reality visual effects film
Published 2017“…‘Token’ is a 4 minutes live-action with augmented reality visual effects film, exploring the techniques of green screen shooting and keying, 2D and 3D compositing, particle simulation, and 2D and 3D animation. …”
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Final Year Project (FYP) -
7
Review of audience gratification with Chinese online film festivals
Published 2024“…Against this backdrop, online film festivals have emerged as a new subject of film festival research. …”
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Article -
8
Deep learning methods for genome-based prediction of drug resistance in Mycobacterium tuberculosis
Published 2023“…Recent years have seen a concerning rise in drug-resistant tuberculosis cases, calling for the development of new approaches for drug susceptibility testing. …”
Thesis -
9
The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films
Published 2013“…The study of the influences of additives on the drug delivery characteristics from PLGA thin films as a coating on angioplasty balloons was reported in this thesis. …”
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Thesis -
10
Formulation and in-vitro release study of drug loaded liposomes for treating dry eye disease
Published 2016“…Thin film hydration method technology is employed to fabricate the liposomes and to encapsulate the drug within its hydrophobic bilayer of the liposomes. …”
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Final Year Project (FYP) -
11
Tantalum based amorphous thin films as copper diffusion barrier
Published 2013“…Guidelines of developing reliable Cu diffusion barrier are drawn base on this study.…”
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Thesis -
12
A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria
Published 2024“…The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. …”
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Journal Article -
13
Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery
Published 2016“…SEM images coupled with image analysis software reveal that different surface morphology of the microparticles have different drug adhesion mechanisms. Comparison of ACI results and image analysis of SEM images shows that an increase in the particle surface roughness can increase the fine particle fractions (FPFs) using the rod-covered mannitol microparticles as drug carriers. …”
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Journal Article -
14
Surface modification of smooth poly (L-lactic acid) films for gelatin immobilization
Published 2013“…Poly(l-lactic acid) (PLLA) is widely used in drug delivery and medical implants. Surface modification of PLLA with functional groups to immobilize gelatin or other extracellular matrix proteins is commonly used to improve its cellular affinity. …”
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Journal Article -
15
Janus particle preparation through UV-induced partial photodegradation of spin-coated particle films
Published 2022“…Photocatalytic titanium dioxide particles prefunctionalized with a surface coating were assembled as particle films via spin-coating on a substrate. The particle films were placed directly under an ultraviolet light source, which induced the photodegradation of the surface coating only on the particle surfaces exposed to the light. …”
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Journal Article -
16
Enabling high performance n-type metal oxide semiconductors at low temperatures for thin film transistors
Published 2020“…Amorphous oxide semiconductors have drawn considerable attention as a replacement for ubiquitous silicon based technologies. …”
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Journal Article -
17
Effects of woven fabric embedment on thin film composite membranes for osmotically driven membrane processes (ODMPs)
Published 2024“…Osmotically driven membrane processes (ODMPs) have drawn a lot of attention in recent years due to their potential applications in water purification, desalination and energy generation. …”
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Final Year Project (FYP) -
18
Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”
Thesis -
19
Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
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Thesis -
20