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Transdermal Drug Delivery
Published 2016“…As each drugs have different molecular properties, operation parameters are varied accordingly. …”
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Final Year Project (FYP) -
2
Aerodynamic optimization and drag minimization for the ultra low cost UAV piquero aerodynamic
Published 2015“…The third segment is a full simulation of the Piquero UAV to determine its lift and drag characteristics. …”
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Final Year Project (FYP) -
3
Nanosized silica particles for achiral drug separation
Published 2009“…It is widely recognized that the full potential of rapid chromatography can be realized with very small support particulates and tailor-made chiral stationary phase. …”
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Research Report -
4
18F-labelling of new chemotypes for drug discovery
Published 2016“…Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.…”
Thesis -
5
Amplifying signals in the tumor microenvironment for drug development and diagnostics
Published 2024“…Leveraging advancements in high throughput screening and in deep learning, we contribute important tools for the effective design of conditional drugs that require the cleavage of a protease substrate to unleash drug cytotoxicity. …”
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Thesis -
6
Investigating viral glycosylation pathways for drug and vaccine development
Published 2021“…</p> <p>The current COVID-19 pandemic has highlighted the urgent need for vaccines and antiviral drugs. The principal topic of my DPhil centres on addressing these needs for viral infection. …”
Thesis -
7
Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases
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Journal Article -
8
Deep learning methods for genome-based prediction of drug resistance in Mycobacterium tuberculosis
Published 2023“…Recent years have seen a concerning rise in drug-resistant tuberculosis cases, calling for the development of new approaches for drug susceptibility testing. …”
Thesis -
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Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Published 2024“…However, realizing the full potential of this approach requires a clear comprehension of the genetic dependencies underlying drug synergy. …”
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Article -
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A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria
Published 2024“…The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. …”
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Journal Article -
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Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Thesis -
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”
Thesis -
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
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Thesis -
14
RES.10-001 Making Science and Engineering Pictures, Fall 2014
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Learning Object -
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AI is a viable alternative to high throughput screening: a 318-target study
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Journal Article -
16
Wind tunnel testing of a ducted-fan unmanned aerial vehicle
Published 2011“…The experiments were carried out in a closed-loop wind tunnel with the full-scale MAV at different configurations. Coefficients of lift, drag and pitching moment were first discussed in a simple configuration of varying pitch angle with different wing setups without the propeller motor. …”
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Final Year Project (FYP) -
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Antimicrobial efficacy testing of antibiotic-containing biodegradable nanopolymers against biofilm and planktonic cells.
Published 2009“…With efficient use of drug-encapsulated nanopolymers, bactericidal dosages are sufficiently lowered and dosing intervals can be extended due to the sustained drug release feature afforded by these efficacious nanocarriers.…”
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Final Year Project (FYP) -
19
Small towing tank for accurate testing of significantly scaled-down ship models
Published 2012“…Flow simulation was completed on the full ship model using the surface capturing approach with the resistance predicted. …”
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Final Year Project (FYP) -
20
Prediction of Intermittent Fluctuations from Surface Pressure Measurements on a Turbulent Airfoil
Published 2024“…Methods include direct prediction from historical pressure measurements, flow reconstruction followed by forward integration using a full order solver, and data-driven dynamic models in various low dimensional quantities. …”
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Article