Evaluation of carob tree (Ceratonia siliqua L.) pods, through three different drying techniques, and ultrasonic assisted extraction, for presence of bioactives by Hussain, Ashiq, Arif, Muhammad Rehan, Ahmed, Adnan, Laaraj, Salah, Firdous, Nida, Ali, Muhammad Qasim, Haya Fatima, ., Yaqub, Shazia, Kauser, Samina, Nisar, Rizwan, Gorsi, Faiza Iftikhar, Ud Din, Ghulam Mueen, Elfazazi, Kaoutar

“…The purpose of this study was to determine how ethanolic extracts of carob pods from Morocco, prepared with ultrasonic assistance were affected by microwave (525 °C for 2.5 min), hot air (65 °C for 16 h), and spray drying (input and output air temperatures 180 and 90 °C, respectively, feed flow rate 2.5 mL/min and 5 bars, respectively), in terms of their physicochemical composition and biological activity. …”
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Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8⁺ T cells by Kang, Xing, Liu, Changan, Ding, Yanqiang, Ni, Yunbi, Ji, Fenfen, Lau, Harry Cheuk Hay, Jiang, Lanping, Sung, Joseph Jao Yiu, Wong, Sunny Hei, Yu, Jun

“…R. intestinalis or butyrate also significantly improved antiprogrammed cell death protein 1 (anti-PD-1) efficacy in mice bearing MSI-low CT26 tumours. Mechanistically, butyrate directly bound to toll-like receptor 5 (TLR5) receptor on CD8(+) T cells to induce its activity through activating nuclear factor kappa B (NF-& kappa;B) signalling. …”
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Patient-Centered Clinical Trial Design for Heart Failure Devices via Bayesian Decision Analysis by Chaudhuri, Shomesh E., Adamson, Phillip, Bruhn-Ding, Dean, Ben Chaouch, Zied, Gebben, David, Rincon-Gonzalez, Liliana, Liden, Barry, Reed, Shelby D., Saha, Anindita, Schaber, Daniel, Stein, Kenneth, Tarver, Michelle E., Lo, Andrew W.

“…This result reflects the willingness of heart failure patients to bear additional risks of the investigational device in exchange for its probable benefits. …”
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Towards Synergistic Understanding of Language Processing in Biological and Artificial Systems by Hosseini Asl, Eghbal

“…Over the past five years, artificial neural networks (ANNs) have achieved capabilities in the comprehension and production of language that are indistinguishable from those of humans, and their internal representations bear similarity to activity within the language network. …”
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Biological characterization of RNA polymerase proteins from human 2009 pandemic H1N1 and low pathogenic avian H5N2 and H9N2 influenza viruses by Myaing, Myint Zu

“…In our gene reassortment study, a single reassortant bearing a human-origin PA or PB2 subunit against an avian polymerase background could overcome the host range barrier of avian polymerase in human 293T cells, indicating the PA or PB2 as a major determinant of species tropism and pathogenicity. …”
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南洋理工大学在籍华族学生婚姻观 = Chinese undergraduates' views on marriage : a case study of Nanyang Technological University by 吴起慧 Goh, Qi Hui

“…Since 1980s, Singapore has been persistently facing the problems of later marriages and delayed child-bearing. These trends could bring much detriment to the country; particularly to the economy and society. …”
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Tumor-targeted nano-assemblies for energy-blocking cocktail therapy in cancer by Chen, Manling, Liu, Yidu, Li, Yang, Liu, Xue

“…In studies with A549 tumor-bearing mice, the combination of low-dose 2-DG and metformin did not impede tumor growth, whereas 2-DG@MA-dots markedly decreased tumor volume, with the mean final tumor volume in the combination treatment group being approximately 89 times greater than that in the 2-DG@MA-dot group. …”
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Comparison of transport methodologies on near-field pollutant dispersion in urban environments using CFD by Tee, Clarence Wei Tat

“…The two methodologies are validated by simulating the dispersion phenomena for two test cases which largely bear resemblance to urban settings: a three-dimensional street canyon setup and the Mock Urban Setting Test (MUST) field experiment. …”
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Synthesis of heavy cyanide analogs for the design of novel Prussian blue analogs by Yang, E

“…In order to provide illustrative points of comparison, analogous metal complexes bearing various strong-field ligands are also synthesized and analyzed using the same approach.…”

Multi-sensor calibration and multi-modal perception for intelligent systems by Zhang, Jun

“…The main novelty is we propose to use the easy-to-obtain objects in the traffic for calibration (cars, trucks, buses, etc.). The essence is we observe that the 3D bounding box centers of the vehicles are viewpoint invariant. …”
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Bacteria-mediated anti-cancer therapy by Bhave, Madhura Satish

“…However, IB significantly inhibited the growth of the tumors and improved the survival rate of immunocompetent CT26 tumor-bearing mice. Histological analysis showed that IB increased the necrotic area in HCT116 tumors. …”
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Export competitiveness in the context of Singapore by Chew, Kheng Lee, Phua, Chin Tiong, Yau, Puay Hiang

“…Last but not least, we must bear in mind that Singapore is only a small economy. …”
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Genome-wide transcriptome profiling reveals molecular response pathways of Trichoderma harzianum in response to salt stress by Yang, Qihong, Mao, Zhenchuan, Hao, Yali, Zheng, Shijie, Zhao, Jianlong, Li, Yan, Yang, Yuhong, Xie, Bingyan, Ling, Jian, Li, Yanlin

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Fabrication and characterization of graphene and carbon nanotube reinforced bioceramic nanocomposites by Hu, Huanlong

“…Bioceramics play an important role in the replacement and regeneration of human tissues, but their intrinsic brittleness and low wear resistance make the monolithic bioceramics still problematic for load-bearing applications. The two dimensional (2D) graphene and one dimensional (1D) carbon nanotube (CNT), as the secondary strong and tough biocompatible nanofillers, are popular nanocarbons to reinforce bioceramics. …”
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Engineered terahertz emission from spintronic heterostructures: amplitude, phase and chirality by Agarwal, Piyush

“…To summarize, the thesis aims to contribute to the synergies of spintronics and photonics for advanced applications in developing scalable devices bearing low-cost fabrication with on-chip compatibility.…”
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Amino-functionalised β-diketiminate ligands (N-nacnacs): Synthesis and coordination chemistry with Main Group elements by Huan, D

“…The establishment of a library of germylenes and stannylenes bearing different N-bound aromatic substituents with varying degrees of steric bulk allows for a systematic study of the steric effects of the flanking aryl groups on the overall molecular metrics of these complexes. …”

Scheduling and resource optimization in rail operations : models and algorithms by Birhade, Mahendra Pandharinath

“…Railway resources such as tracks, overhead equipment, locomotives, passenger and freight cars require huge capital investments and long lead time for procurement and installation. …”
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Stability improvement and control optimization of isolated two-stage AC-DC-DC converter systems by Feng, Fan

“…The analysis results offer instructive implications to fine-tune the design rules of the DAB converters. Bearing the mind that the impedance model of the DAB converter is closely related to the modulation schemes, the impacts of three typical modulation methods on the DAB impedances are analyzed and compared. …”
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Towards robust sensing and recognition : from statistical learning to transfer learning by Yang, Jianfei

“…Secondly, current domain adaptation methods require careful manual hyper-parameter tuning, which is not realistic for unmanned systems such as smart cars. To stabilize the training of adversarial domain adaptation, Max-margin Domain-Adversarial Training (MDAT) is developed in this thesis to realize stable convergence without cumbersome manuals. …”
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