Uptake and safety of Sotrovimab for prevention of severe COVID-19 in a cohort and self-controlled case series study by Patone, M, Snelling, AJ, Tibble, H, Coupland, C, Sheikh, A, Hippisley-Cox, J

“…Results: Here we show that among treated and untreated eligible individuals, the mean ages (54.6 years, SD: 16.1 vs 54.1, SD: 18.3) and sex distribution (women: 60.9% vs 58.1%; men: 38.9% vs 41.1%) are similar. …”

Predictive factors for the diagnosis of coeliac disease in children and young people in primary care: A systematic review and meta-analysis by Farrier, CE, Wanat, M, Harnden, A, Paterson, A, Roberts, N, Saatci, D, Hirst, J

“…Included studies were observational or randomized trials reporting the risk of CD when exposed to predictive factor(s) in people ≤25 years of age. Genetic factors were excluded. Risk of Bias was assessed using the Newcastle-Ottawa Scale. …”

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study by Carter, AR, Gill, D, Davies, NM, Taylor, AE, Tillmann, T, Vaucher, J, Wootton, RE, Munafò, MR, Hemani, G, Malik, R, Seshadri, S, Woo, D, Burgess, S, Davey Smith, G, Holmes, MV, Tzoulaki, I, Howe, LD, Dehghan, A

“…Results: Each additional standard deviation of education (3.6 years) was associated with a 13% lower risk of coronary heart disease (odds ratio 0.86, 95% confidence interval 0.84 to 0.89) in observational analysis and a 37% lower risk (0.63, 0.60 to 0.67) in mendelian randomisation analysis. …”

The prognostic impact of minimally invasive esophagectomy on survival after esophagectomy following a delayed interval after chemoradiotherapy; a secondary analysis of the DICE stu... by Markar, SR, Sgromo, B, Evans, R, Griffiths, EA, Alfieri, R, Castoro, C, Gronnier, C, Gutschow, CA, Piessen, G, Capovilla, G, Grimminger, PP, Low, DE, Gossage, J, Gisbertz, SS, Ruurda, J, van Hillegersberg, R, D'journo, XB, Phillips, AW, Rosati, R, Hanna, GB, Maynard, N, Hofstetter, W, Ferri, L, Berge Henegouwen, MI, Owen, R

“…<p><strong> Results: </strong></p> 428 patients (145 MIE and 283 OE) had surgery between 12 weeks and two years after CRT. Significant differences were observed in ASA grade, radiation dose, clinical T stage, and histological subtype. …”

Effectiveness and safety of COVID-19 vaccination in people with blood cancer by Copland, E, Hirst, J, Mi, E, Patone, M, Chen, D, Coupland, C, Hippisley-Cox, J

“…</p> <br> <p><strong>Methods:</strong> Individuals aged ≥12 years as of 1st December 2020 in the QResearch primary care database were included. …”

Determining targets for antiretroviral drug concentrations: a causal framework illustrated with pediatric efavirenz data from the CHAPAS-3 trial by Schomaker, M, Denti, P, Bienczak, A, Burger, D, Díaz, I, Gibb, DM, Walker, AS, McIlleron, H

“…</p> <p><strong>Methods:&nbsp;</strong>The proposed framework is applied in an analysis including longitudinal observational data from 125 HIV-positive children treated with efavirenz-based regimens within the CHAPAS-3 trial, which enrolled children &lt;&thinsp;13&thinsp;years in Zambia/Uganda. A directed acyclic graph was developed to visualize the mechanisms affecting antiretroviral concentrations. …”

A 24-month National Cohort Study examining long-term effects of COVID-19 in children and young people by Stephenson, T, Pinto Pereira, SM, Nugawela, MD, Dalrymple, E, Harnden, A, Whittaker, E, Heyman, I, Ford, T, Segal, T, Chalder, T, Ladhani, SN, McOwat, K, Simmons, R, Xu, L, Fox-Smith, L, Shafran, R

“…Methods: CloCk is a cohort of CYP in England aged 11-to-17-years when they had a SARS-CoV-2 PCR-test (between September 2020 and March 2021). …”

Accessibility, inclusivity, and implementation of COVID-19 clinical management guidelines early in the pandemic: a global survey by Pilbeam, C, Malden, D, Newell, K, Dagens, A, Kennon, K, Michelen, M, Gobat, N, Sigfrid, L

“…Only 20% of respondents reported having access to CMGs covering care for children, 25% for pregnant women, and 50% for older adults (>65 years). Identified themes were for CMGs to include recommendations for at-risk populations and settings, include supportive care guidance, and be updated as evidence emerges, and for clinicians to have training and access to recommended treatments to support implementation. …”

Response of appetite and potential appetite regulators following intake of high energy nutritional supplements by Fatima, S, Gerasimidis, K, Wright, C, Tsiountsioura, M, Arvanitidou, E-I, Malkova, D

“…</p> <p><strong>Design</strong> Twenty three females of 24.4 ± 2.8 years with BMI of 18.2 ± 0.8 kg/m2 consumed HENSD (2.5 MJ) or PLACEBO (0.4 MJ) in fasted state in a single blind randomized cross-over study. …”

Non-stationary modeling of seasonal precipitation series in Turkey: estimating the plausible range of seasonal extremes by Tosunoglu, F, Slater, LJ, Kowal, KM, Gu, X, Yin, J

“…Using the non-stationary models, we then computed seasonal precipitation estimates for different return periods (i.e., 20, 50, and 100 years) and considered the minimum and maximum possible extreme precipitation scenarios at each site. …”

Knowledge, attitude and practice on cardiopulmonary resuscitation (cpr) among critical care nurses in Hospital Universiti Sains Malaysia by Mughni, Muhamad Hafizuddin

“…The chi-square test result (χ² = 22.609, p < 0.001) suggests a significant association between the years of working experience in critical care and the level of knowledge.…”
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PostIndependentzia by Calzada, I

“…This core idea of this book is that the Basque Country, due to its own intricacies rather than merely as a consequence of its being kidnapped and held captive by the old-fashioned Spanish and French state legal frameworks, has come, over the years, to develop many points of inertia that are inherent in its territorial policies and strategies. …”

Supporting activex-based client for large-scale collaborative virtual environment by Wu, Liang.

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Physical unclonable function based solutions to unification of user, device and data authentication by Zheng, Yue

“…These solutions are typically realized using conventional techniques that require the safekeeping of a secret binary key in the non-volatile memory, or battery-backed SRAM of some device, or a token owned by the user, which have been proven to be vulnerable to various kinds of invasive, semi-invasive and side channel attacks. …”
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Nature-inspired lightweight auxetic structures for enhanced stiffness and absorption capacity by Zhang, Ee Teng

“…Traditionally, gradients in these structures have been introduced through variations in thickness. …”
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Semantic scene understanding on 3D point clouds by Dong, Shichao

“…While standard methods like rotations and flips have been common, they often lack high-level diversity. …”
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Tracking and detecting objects in image sequence by Wang, Li

“…Although many promising methods have been proposed in this area, it is still very challenging to track and detect arbitrary objects due to issues such as complicated motion transformations and occlusions. …”
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Development of human enterovirus 71 nano calcium phosphate adjuvanted candidate vaccine for parenteral and mucosal delivery by Saeed Ahmed, Mohamed Ibrahim

“…Chitosan loaded nano-adjuvant offered ascending and extended vaccine antigen release, due to its smaller adjuvant size and reversibility of interaction, but not in alginate-adjuvant formulations, due the vaccine been sequestered in the calcium-alginate chemical crosslink. …”
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#Hooked? Extending the social cognitive model in examining the antecedents of problematic social network sites use among Singaporean adolescents and adults by Lee, Edmund Wei Jian

“…Cases of social network sites (SNSs) users potentially developing problematic SNSs use have revived scholarly interest in addictive media research in the last few years. As a nascent research area, there is a need for clear communication-centric theoretical paradigms and rigorous methods in guiding empirical inquiry in problematic SNSs use. …”
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Integrating quantitative and qualitative methodologies to build a national R&amp;D plan using data envelopment analysis based on R&amp;D stakeholders’ perspectives by Park, Wan, Kim, Sang-Gook

“…The yearly increase in government R&amp;D investment and top-down national R&amp;D investment allocation requires a more quantitative decision-making system that maximizes R&amp;D performance and efficient budget allocation. …”
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