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11821
Cohort differences in physical health and disability in the United States and Europe
Published 2024“…<p><strong>Objectives</strong></p> Declines in mortality have historically been associated with improvements in physical health across generations. …”
Journal article -
11822
Characterisation of the genomes of brain metastases
Published 2015“…Interventions include surgery and stereotactic radiosurgery with few metastases, with whole brain radiotherapy serving a role in patients with several metastases. In recent years, there have been increased efforts directed towards early phase trials to address the role of targeted biological agents towards pathogenic drivers namely, <em><b>EGFR, HER2</b></em> and <em><b>BRAF</b></em>. …”
Thesis -
11823
Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…Part II: Small Peptide and Membrane Lipid Based Self-assembled Nanostructures for Controlled Drug/gene Delivery The usage of nanoscale materials may greatly facilitate the development of novel therapeutic methods for controllable release of bioactive agents at location of diseases with desired dosage, which has been considered to be of clinical significance to guarantee the curative effect while minimizing the drug resistance and other side effects.8-10 Among the available nanocarriers, the self-assembled nanostructures from highly biocompatible materials (e.g. oligo-peptide, membrane lipids, etc) have been extensively studied due to their unique features of high water content, high drug/gene loading efficiency and promising therapeutic effect.11-13 More importantly, they are naturally biocompatible and biodegradable thus ensuring desirable bio-safety, whereas in terms of inorganic nanoparticle-based delivery systems, additional surface modifications were often required to achieve a good biocompatibility. …”
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Thesis -
11824
Uncertainty quantification framework for combined statistical spatial downscaling and temporal disaggregation for climate change impact studies on hydrology
Published 2017“…The extension of the single site SDM to multi-site SDM has been considered as the next step to downscale the climate variable observations at multiple sites simultaneously. …”
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Thesis -
11825
Novel method of probe design for characterising unclassified microbial taxa in wastewater
Published 2017“…Thus far, FISH-FACS with RiboProbe is the only method that has been used for the enrichment and genome recovery of these two unclassified taxa. …”
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Thesis -
11826
Mapping refuse profile in Singapore old dumping ground through electrical resistivity, S-wave velocity and geotechnical monitoring
Published 2015“…The purpose of this study was to track the refuse profile in Lorong Halus Dumping Ground, the largest landfill in Singapore, by electrical resistivity and surface wave velocity after 25 years of closure. Data were analyzed using an orthogonal set of plots by spreading 24 lines in two perpendicular geophone-orientation directions. …”
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Journal Article -
11827
Cytogenetic and molecular aberrations of multiple myeloma patients : a single-center study in Singapore
Published 2015“…Methods-Forty-five newly-diagnosed, morphologically confirmed patients comprising 18 males and 27 females, aged 46-84 years (median 65 years) were investigated by karyotyping and fluorescence in situ hybridization (FISH). …”
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Journal Article -
11828
Advanced code reuse attacks against modern defences
Published 2019“…The result shows that in addition to the cases that have been discovered in previous work, our tool is able to find more cases of non-blinded constant. …”
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Thesis -
11829
EMC-Compatible Shielding : Magnetic Materials for Shielding - Practical Examples - Device Design /
Published [202“…Shielding for ensuring EMC in high-frequency and radar technology has been developing with ever increasing dynamics since about 1960. …”
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11830
Test Automation Engineering Handbook : Learn and Implement Techniques for Building Robust Test Automation Frameworks /
Published 2023“…Understand test automation and implement it in Web, Mobile, and APIs effectively Key Features Learn how to automate your tests with the help of practical examples Understand how to bridge the gap between testing and test automation Explore test automation strategies for different platforms Book Description This book helps you build a better understanding of test automation and aids in bridging the gap between testing and test automation. The book has been divided into three sections with the first section focusing on preparing you for testing and test automation fundamentals. …”
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software, multimedia -
11831
Rigid-strut-containing crown ethers and [2]catenanes for incorporation into metal-organic frameworks
Published 2014“…The binding behavior of BPP34C10DA with 1,1′-dimethyl-4,4′-bipyridinium bis(hexafluorophosphate) (DMBP⋅2 PF6) has been investigated by means of UV/Vis, fluorescence, and NMR spectroscopic techniques. …”
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Journal Article -
11832
Novel heat treatment methodology for residual stress relieve of AlSi10Mg without compromise of mechanical strength
Published 2021“…Additive manufacturing (AM) has made the fabrication of complex parts possible which otherwise, would not have been possible with conventional subtractive manufacturing. …”
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Thesis-Doctor of Philosophy -
11833
Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy
Published 2022“…Clinical applications of nanozyme-initiated chemodynamic therapy (NCDT) have been severely limited by poor catalytic efficiency of nanozymes, insufficient endogenous H2O2 content, and off-target consumption. …”
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Journal Article -
11834
Conservation of red blood cell signalling in Plasmodium merozoite invasion
Published 2023“…Invasion inhibitory effects of antibodies against RH5 and Basigin have been shown to significantly block merozoite invasion, but an invasion-targeted drug intervention approach have not been well-understood. …”
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Thesis-Doctor of Philosophy -
11835
Dynamic boundaries of acceptable play: a mixed methods examination into players' interpretations of toxic behavior in multiplayer online games
Published 2024“…Scholarship on toxic behavior in multiplayer online games has largely focused on examining its causes and effects. However, there has been less work on defining the concept—for example, what it means and entails. …”
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Thesis-Doctor of Philosophy -
11836
Constraint satisfaction approach to product configuration with cost estimation
Published 2013“…Due to the dynamism and heterogeneity of today’s markets, mass customization has been widely applied in the manufacturing industry with the objective of satisfying individual customer needs while maintaining near mass production efficiency. …”
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Thesis -
11837
Photonic engineering of terahertz quantum cascade lasers
Published 2015“…Therefore, much effort has been placed on the development of new and appropriate THz sources, and in particular with a focus on the development of electrically pumped, semiconductor-based light sources that can be mass produced. …”
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Thesis -
11838
Compact transformer based power combination techniques for millimeter-wave CMOS power amplifiers
Published 2016“…In the realm of millimeter-wave (mm-wave), the V-band centred at 60 GHz has been demonstrated to be the most promising frequency range for short range communication applications such as high data rate transfer systems. …”
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Thesis -
11839
Injectable and biomimetic poly (ethylene glycol) hydrogel systems for in situ therapeutic cell delivery
Published 2017“…Biomimetic poly (ethylene glycol) (PEG)-based hydrogels have been widely explored as extracellular matrix (ECM) mimicking hydrogels as they conserve the advantages of both ECM (cell-responsive molecules) and synthetic hydrogels (controllable structure and mechanical properties), but did not mimic natural ECM well enough due to limited instructive cues. …”
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Thesis -
11840
New algorithms for hardware-efficient implementation of sign detection and magnitude comparison in residue number systems
Published 2017“…First and foremost, a new fast and area-efficient adder-based sign detector for RNS {2n−1, 2n, 2n+1} has been proposed. The circuit is greatly simplified by shrinking the dynamic range to eliminate large modulo operations with the help of the new Chinese remainder theorem (CRT)-I. …”
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Thesis