Cytogenetic and molecular aberrations of multiple myeloma patients : a single-center study in Singapore by Ng, Yit Jun, Tan, Yu Min, See, Karen Hsu Shien, Choo, Natasha Swee Lian, Lim, Sherry Xin Er, Lim, Alvin Soon Tiong, Lim, Tse Hui, Yee, Yenny, Lau, Lai Ching, Tien, Sim Leng, Sathish, Kumar, Tan, Daryl Chen Lung

“…Background-Much is known about the cytogenetic lesions that characterize multiple myeloma (MM) patients from the USA, Europe, and East Asia. However, little has been published about the disease among Southeast Asians. …”
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Negative auto-regulation of myostatin expression is mediated by SMAD3 and microRNA-27 by Ge, XiaoJia, McFarlane, Craig, Vajjala, Anuradha, Arigela, Harikumar, Lokireddy, Sudarsanareddy, Bonala, Sabeera, Manickam, Ravikumar, Kambadur, Ravi, Sharma, Mridula

“…In fact, loss of Mstn has been shown to result in increased post-natal muscle growth through enhanced satellite cell functionality; while elevated levels of Mstn result in dramatic skeletal muscle wasting through a mechanism involving reduced protein synthesis and increased ubiquitin-mediated protein degradation. …”
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Message from ICME'12 technical program chairs by Cai, Jianfei, Hanjalic, Alan, Magli, Enrico, Pickering, Mark, Friedland, Gerald, Hua, Xian-Sheng

“…ICME has been a flagship international conference for the presentation of novel and fundamental research advances in the field of Multimedia since 2000. …”
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Evidence-based roadmap for geoheritage conservation in southeast Arabia: Inventory, evaluations, and communicating geocultural connections by Sayama, K

“…</p> <p>First, a GIS-based study was conducted to identify the status quo of Quaternary geosites that have been studied in this region. Second, a science communication study was carried out to test the efficacy of highlighting the human-nature interconnection in introducing Quaternary geoheritage sites. …”

Understanding customer retrials in call centers: preferences for service quality and service speed by Hu, K, Allon, G, Bassamboo, A

“…<p><strong> Academic/practical relevance: </p></strong> Little empirical research has been done to understand customers’ strategic retrials, and theoretical research studies retrials by assuming the degree to which pickup speed and service quality impact retrials. …”

Attack strategies in birds of prey by Brighton, C

“…The deep fovea is optimised for long-range vision, and is directed at approximately 45° to the side of the head. It has been proposed that the head is held in line with the body for streamlining, while the body is turned in flight to fixate the image of the prey on the deep fovea, resulting in a curved trajectory. …”

Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation by Søgaard, P

“…In contrast, loss of polarity has been associated with progression of diseases such as cancer. …”

Integrated transcriptomic and proteomic profiling of responses to clinical and novel bisphosphonates by Lu, J

“…<p>Bisphosphonates have traditionally been used to treat bone resorptive disorders by inhibiting osteoclast activity. …”

High-speed indoor MIMO visible light communications by Dong, F

“…Two receiver designs have also been employed: A seven-channel angle diversity receiver (ADR) and an aperture-based receiver (ABR). …”

Actuator disk methods for tidal turbine arrays by Hunter, W

“…Although it is impractical to array real turbines across the entire width of a channel it has been proposed to use short arrays of turbines making use of local constructive interference (blockage) effects; Nishino &amp; Willden (2012) showed that although the phenomenal power limits of Garrett &amp; Cummins are unobtainable in a real flow, a significant uplift in the limit of power extraction can be achieved for short fences of turbines arrayed normally to the flow in wide cross-section channels. …”

Tri-layer tissue engineering heart valve based on collagen, elastin and hyaluronic acid by Ma, Z

“…Between the clinically used mechanical and bioprosthetic valves, thrombosis, calcification, and incompatibility to somatic growth have been the limiting factors. Tissue engineering heart valve scaffolds, especially those constructed with naturally derived materials, have proven biocompatible and promising candidates for future-generation heart valve replacements.…”

Sensorimotor control of Drosophila copulation by Herbert, MR

“…As with most sequences of motor action, mechanosensory inputs have long been thought to be important for the male to achieve and maintain this position,although until now we have understood very little about the function or properties ofthe sensory neurons involved.…”

Les sanctions coutumières comme gage de la paix et de la sécurité chez les traditionnalistes moundang du Nord-Cameroun by Dekane, E

“…These punishments, which have now been overturned, put witches, murderers, adulterers and other exorcists out of action, thereby promoting peace and security.…”

Discovering genetic modifiers in Niemann-Pick Disease Type C by Rodriguez-Gil, J

“…Miglustat (Zavesca) is the only approved therapy for NPC, and while it has been shown to improve clinical outcomes it is not a cure. …”

Indicators of Global Climate Change 2023: annual update of key indicators of the state of the climate system and human influence by Forster, PM, Smith, C, Walsh, T, Lamb, WF, Lamboll, R, Hall, B, Hauser, M, Ribes, A, Rosen, D, Gillett, NP, Palmer, MD, Rogelj, J, von Schuckmann, K, Trewin, B, Allen, M, Andrew, R, Betts, RA, Borger, A, Boyer, T, Broersma, JA, Buontempo, C, Burgess, S, Cagnazzo, C, Cheng, L, Friedlingstein, P, Gettelman, A, Gütschow, J, Ishii, M, Jenkins, S, Lan, X, Morice, C, Mühle, J, Kadow, C, Kennedy, J, Killick, RE, Krummel, PB, Minx, JC, Myhre, G, Naik, V, Peters, GP, Pirani, A, Pongratz, J, Schleussner, C-F, Seneviratne, SI, Szopa, S, Thorne, P, Kovilakam, MVM, Majamäki, E, Jalkanen, J-P, van Marle, M

“…Human-induced warming has been increasing at a rate that is unprecedented in the instrumental record, reaching 0.26 [0.2–0.4] °C per decade over 2014–2023. …”

Psychiatric comorbidities in persons with epilepsy compared with persons without epilepsy: a systematic review and meta-analysis by Kwon, C-S, Rafati, A, Ottman, R, Christensen, J, Kanner, AM, Jetté, N, Newton, CR

“…<p><strong>Importance</strong> Several psychiatric disorders have been found to occur more frequently in persons with epilepsy (PWE) than in persons without epilepsy.…”

Understanding lived experiences of bereaved parents of children with chronic life-threatening Illness : towards a culture-specific and meaning-oriented narrative E-writing interven... by Dutta, Oindrila

“…In Singapore, while deaths among children and youths (age<19) have been steadily declining over the past decade, the number of child deaths caused by chronic conditions has increased by about 27% from 120 in 2014 to 152 in 2016. …”
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Exploring and Exploiting Ribonuclease 1: from Protein Biochemistry to Protein Engineering by Wralstad, Evans Christian

“…RNase 1 and its bovine homologue RNase A exhibit ubiquitous expression across tissues, a catalytic efficiency within the diffusion-limited regime, and minimal substrate sequence requirements. RNase A has been a favorite model protein of biochemists for over half a century; due to the high level of sequence conservation between RNase A and RNase 1, many observations made for RNase A have corollaries for RNase 1. …”
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Controlling the assembly of proteins and cells on SiO₂ surfaces by Seong, Jiehyun, 1973-

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Rail transit OD matrix estimation and journey time reliability metrics using automated fare data by Chan, Joanne, S.M. Massachusetts Institute of Technology

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