Use of intravenous immunoglobulin for the treatment of autoimmune encephalitis: audit of the NHS experience by Kinsella, JA, Irani, SR, Hollingsworth, R, O’Shaughnessy, D, Kane, P, Foster, M, Schott, JM, Lunn, MP

“…To date, however, evidence for the use of intravenous immunoglobulin in this context comes from case series/expert reviews as no controlled trials have been performed. We aimed to analyse the NHS England Database of intravenous immunoglobulin usage, which was designed to log use and guide procurement, to explore usage and therapeutic effect of intravenous immunoglobulin in autoimmune encephalitis in England.…”

Deciphering the mechanisms of cross-presentation for exogenous ROPs through their interaction with cathepsin S by Stephens, AJ

“…Each overlapping segment is separated by a cathepsin S cleavage site for processing within dendritic cells to promote antigen cross-presentation and an anti-tumour response. ROPs have been designed with the LRMK linker to target cathepsin S, a key mediator in the vacuolar pathway of cross-presentation. …”

The Athenian dramatic chorus in the fourth century BC by Jackson, LCM

“…Amid the recent scholarly interest in the rapid expansion of the theatre industry from the late fifth-century BC onwards, no study has been made of a central, defining even, element of ancient Greek drama at that time – the chorus. …”

A dormant overmassive black hole in the early Universe by Juodžbalis, I, Maiolino, R, Baker, WM, Tacchella, S, Scholtz, J, D’Eugenio, F, Witstok, J, Schneider, R, Trinca, A, Valiante, R, DeCoursey, C, Curti, M, Carniani, S, Chevallard, J, de Graaff, A, Arribas, S, Bennett, JS, Bourne, MA, Bunker, AJ, Charlot, S, Jiang, B, Koudmani, S, Perna, M, Robertson, B

“…Several different models have been proposed to explain these findings, ranging from heavy seeds to light seeds experiencing bursts of high accretion rate10, 11, 12, 13, 14, 15–16. …”

A realist evaluation to explain and understand the role of paramedics in primary care by Eaton, G, Wong, G, Tierney, S, Williams, V, Mahtani, KR

“…However, the specific contribution paramedics can offer to the primary care workforce has not been distinctly outlined. We used realist approaches to understand the ways in which paramedics impact (or not) the primary care workforce. …”

DNA-damage orchestrates self-renewal and differentiation via reciprocal p53 family and Hippo/Wnt/TGF-β pathway activation in embryonic stem cells by Ye, Y, Xie, W, Wang, X, Tan, S, Yang, L, Ma, Z, Zhu, Z, Chen, X, Liu, X, O’Neill, E, Chang, L, Zhang, W

“…DNA damage and repair mechanisms have been largely elucidated in mutated cancer cells or simple eukaryotes, making valid interpretations on early development difficult. …”

Impact of precursor dosing on the surface passivation of AZO/AlOx stacks formed using atomic layer deposition by Wang, Y, Hobson, TD, Swallow, JEN, McNab, S, O'Sullivan, J, Soeriyadi, A, Niu, X, Fraser, RC, Dasgupta, A, Maitra, S, Altermatt, P, Weatherup, RS, Wright, M, Bonilla, RS

“…In addition, AZO has also been shown to passivate the c-Si surface. The ability for one material to provide all three properties without requiring any indium is advantageous in single junction and tandem solar devices. …”

Methodology research in clinical studies for Neglected Tropical Diseases (NTDs) of the skin: Addressing design, conduct and relevance for context and target population by Erber, A

“…</p> <p>Patients reported a number of treatment outcomes as important; the majority had only been insufficiently or not included in trials so far. …”

Disruption of seasonal influenza circulation and evolution during the 2009 H1N1 and COVID-19 pandemics in Southeastern Asia by Chen, Z, Tsui, JL, Cai, J, Su, S, Viboud, C, du Plessis, L, Lemey, P, Kraemer, MUG, Yu, H

“…East, South, and Southeast Asia (together referred to as Southeastern Asia hereafter) have been recognized as critical areas fuelling the global circulation of seasonal influenza. …”

Fatty acid composition of milk of refugee Karen and urban Korean mothers. Is the level of DHA in breast milk of Western women compromised by high intake of saturated fat and linole... by Golfetto, I, McGready, R, Ghebremeskel, K, Min, Y, Dubowitz, L, Nosten, F, Drury, P, Simpson, JA, Arunjerdja, R, Crawford, MA

“…<p><b>Background:</b> Lower proportions of docosahexaenoic acid (DHA) and total n-3 metabolites have been reported in breast milk of European, Australian and North American women compared with milk of mothers from non-Western countries. …”

How ready is general practice to improve quality in chronic kidney disease? A diagnostic analysis by Crinson, I, Gallagher, H, Thomas, N, de Lusignan, S

“…CKD guidelines may have been introduced without sufficient educational support.…”

Jamaican customs data, c. 1800-45 by Graham, A, Lavallee, E

“…However, commodities and units were not reported consistently, with rum, for example, being reported in barrels, casks, hogsheads, kegs and puncheons. These have been left as they were in the original.</p> <p>Information on the typical volumes and capacities of these containers, and the prices of commodities, can be found in the secondary literature: B.W. …”

Local rainfall is more likely than distant thunderstorms to affect movement behaviour in Northern Kenyan elephants by Mulder, T, Mortimer, B, Ferwerda, J, Vollrath, F

“…Previous research indicates that African savanna elephants change their movements preceding or coincident with local rainfall and it has been suggested that they respond to thunder in remote storms–perhaps reading seismic cues. …”

Stereoselective cyclisation cascades mediated by carbon electrophiles to access novel polycyclic scaffolds by Aynetdinova, DA

“…The cation-initiated polyene cyclisation to form carbocyclic rings, as well as heterocyclisation to form novel lactones, has been explored. High levels of diastereoselectivity in setting up new stereocentres during the cyclisation were achieved. …”

Molecular features associated with response to enasidenib plus azacitidine in newly diagnosed IDH2-mutated acute myeloid leukemia by Risueño, A, See, WL, Prebet, T, DiNardo, C, Döhner, H, Stein, EM, Fathi, AT, Vyas, P, Quek, L, Gandhi, A, Hasan, M

“…Of note, combination therapy improved event-free survival in patients with RAS-pathway mutations, which have been associated with resistance to enasidenib monotherapy. …”

Iranian and Saudi mutual (mis)representations: a study of the relationship between discourses of othering, political confrontation and sectarian strife by Mohammad, T

“…</p> <p>The study findings identify a paradigm shift in analysis of the Saudi-Iranian relationship, moving away from conventional geopolitical and sectarian paradigms, which have been dominant. I conclude that religious and sectarian identities remained a propaganda tool, whereas, the nature of the agenda promoted by both sides was political in nature. …”

Ottoman painting and painters during the First World War by Tongo, G

“…In modern Turkish history and art history too, the art of the war years has either been overlooked―buried in the images of the Independence War that followed―or distorted for ideological purposes―emphasizing the militaristic and pro-war aspects of wartime artworks and marginalizing or excluding non-Muslim Ottoman artists from the story. …”

A simulation study showed that linear regression and Mann-Whitney test can be used to analyse the Days Alive and at Home by day 30 (DAH30) outcome in a randomized controlled trial by Cook, J

“…</p> <br> <p><strong>Study Design and Setting:</strong> The days alive and at home by day 30 (DAH30) has been proposed a patient-centric outcome, and clinically relevant outcome suitable for clinical trials. …”

Essays on time series econometrics and financial econometrics by Xu, W

“…</p> <p>Time-varying volatility is common in macroeconomic data and has been incorporated into macroeconomic models in recent work. …”

HGVS Nomenclature 2024: improvements to community engagement, usability, and computability by Hart, RK, Fokkema, IFAC, DiStefano, M, Hastings, R, Laros, JFJ, Taylor, R, Wagner, AH, den Dunnen, JT

“…Methods: The HGVS Variant Nomenclature Committee (HVNC) now operates under the Human Genome Organization (HUGO), facilitating broader community feedback and collaboration with related standards organizations. The website has been redesigned using modern documentation tools and practices. …”