Incidence and mortality rates of 14 site-specific infectious diseases in 10 diverse areas of China: findings from China Kadoorie Biobank, 2006-2018 by Huang, R, Kartsonaki, C, Turnbull, I, Pei, P, Chen, Y, Liu, J, Du, H, Sun, D, Yang, L, Barnard, M, Lv, J, Yu, C, Chen, J, Li, L, Chen, Z, Bragg, F

“…During the 12 years of follow-up, 101,673 participants were hospitalized for any infectious disease. …”

A hand-targeted auxiliary personal protective equipment for intervention of fomite transmission of viruses by Tan, Justin Kok Soon, Song, Shang Wei, Zeng, Jialiu, Lo, Chih Hung

“…In COVID-19, fomite transmission has been shown to be a major route for the spreading of the SARS-CoV-2 virus due to its ability to remain on surfaces for extended durations. …”
Get full text

De-risking clinical trial failure through mechanistic simulation -- simulation code by Brown, L, Brown, L

“…<p>This code was written two years ago and used to generate results for a manuscript of the same title.…”

Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases by Vinogradova, Y, Coupland, C, Hippisley-Cox, J

“…In recent oestrogen only users, between three (in younger women) and eight (in older women) extra cases per 10 000 women years would be expected, and in oestrogen-progestogen users between nine and 36 extra cases per 10 000 women years. …”

Understanding the intermittency of the wintertime North Atlantic Oscillation and East Atlantic Pattern seasonal forecast skill in the Copernicus C3S multi-model ensemble by Baker, L, Shaffrey, L, Johnson, S, Weisheimer, A

“…The wintertime North Atlantic Oscillation (NAO) and East Atlantic Pattern (EA) are the two leading modes of North Atlantic pressure variability and have a substantial impact on winter weather in Europe. The year-to-year contributions to multi-model seasonal forecast skill in the Copernicus C3S ensemble of seven prediction systems are assessed for the wintertime NAO and EA, and well-forecast and poorly-forecast years are identified. …”

The battle for Asia in crude oil markets: an easier road ahead for India? by Sen, A

“…Even though the drop in prices is unlikely to last (given the high cost on the supply side) and prices are likely to pick back up to at least the US$80–100 per barrel range in the coming years, India will remain in a privileged position compared to a few years ago, as the continued growth of US tight oil means producers from all around the world will still focus on Asia to sell their crude. …”

Collective reflective equilibrium, algorithmic bioethics and complex ethics by Savulescu, J

“…Resources should be provided to ensure people have a fair innings—when Harris first wrote this, around 70 years of life, but perhaps now 80. Secondly, Harris famously advanced the egalitarian position in response to utilitarian approaches to allocation (such as maximizing Quality Adjusted Life Years [QALYs]) that what people want is the greatest chance of the longest, best quality life for themselves, and justice requires treating these claims equally. …”

Injustice: why social inequality still persists (revised edition) by Dorling, D

“…In the five years since the first edition of Injustice there have been devastating increases in poverty, hunger and destitution in the UK. …”

Progressive encephalomyelitis with rigidity: a Taiwanese case and review of literature by Chang, A, Lin, K-Y, Chuang, K-J, Waters, P, Irani, SR, Mgbachi, V, Yeh, H-L, Lien, L-M, Chiu, H-C, Chen, W-H

“…<p><strong>Conclusion</strong></p> We recommend tumor surveillance up to 2 years in patients with PERM and early administration of immunotherapies and maintain with non-steroid immunotherapy with or without oral corticosteroid for a minimum of 2 years to reduce the risk of relapse in GlyR-Ab-positive patients.…”

Hot and round: How temperature and shape impact the multisensory appreciation of cornmeal by Juravle, G, Duca, R, Feghiuș, C, Spence, C

“…In a between-participants experimental design conducted in an ecologically-valid restaurant setting, we investigated the appreciation of differently-shaped pieces of cornmeal (rounded vs. rectangular) for different serving temperatures (room-temperature vs. hot presentation). 282 participants (165 female, mean age of 37 years, SD = 11 years, age range 17–62 years) tasted the cornmeal and evaluated it with respect to several sensorial qualities (i.e., temperature, wetness, texture, elasticity, and liking) and indicated the perceived dominant taste from amongst the five basic tastes. …”

中国成年人文化程度与体格指标的长期变化关系 by Tan, Y, Shen, Z, Yu, C, Guo, Y, Bian, Z, Pei, P, Du, H, Chen, J, Chen, Z, Lyu, J, Li, L

“…Both body weight and waist circumference (WC) increased with age. From age 25 years to baseline survey (mean age 45.2±6.5), the mean weight change per 5-year was (1.70±2.63) kg for men and (1.27±2.10) kg for women. …”

Comparative legal history: methodology for morphology by Dyson, M

“…This chapter discusses the boundaries, terminology and purpose of methodology and a collection of five methodological steps that can assist in doing comparative legal history, drawing on examples from a range of legal systems in the last 200 years.…”

The Trapezuntine poems in Panagiou Taphou 370 by Lauxtermann, MD

“…Panagiou Taphou 370 (commonly attributed to Stephen Sgouropoulos) and identify references to historical events that took place in Trebizond during the first thirty years of the fifteenth century.…”

Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets by Burchardt, JM, Mei, XW, Ranger, T, McDermott, CJ, Radunovic, A, Coupland, C, Hippisley-Cox, J

“…The median age of diagnosis was 72 years. Peak incidence occurred in the 80–84 year age group in men and 75–79 in women. …”

Exploring and Exploiting Ribonuclease 1: from Protein Biochemistry to Protein Engineering by Wralstad, Evans Christian

“…Efforts to establish a zymogen directed toward the coronavirus SARS-CoV-2 are described in two parts of this thesis. …”
Get full text
Get full text

Covid-19 antibody discovery with topology-enhanced learning models by Wang, Zihong

“…The recent global spread of Coronavirus disease 2019 (COVID-19) has been fueled by the appearance of various new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including Alpha, Beta, Gamma, Delta, Omicron, etc. …”
Get full text

The relationship between leisure time physical activity patterns, Alzheimer’s disease markers and cognition by James, S, Sudre, CH, Barnes, J, Cash, DM, Chiou, Y, Coath, W, Keshavan, A, Lu, K, Malone, I, Murray-Smith, H, Nicholas, JM, Orini, M, Parker, T, Almeida-Meza, P, Fox, NC, Richards, M, Schott, JM

“…Findings drawn from 468 participants (49% female) demonstrated a direct association between being active before 50 years old (≤43 years) and throughout life (up to age 69 years), with larger hippocampal volume at age 70 (P &lt; 0.05). …”

Detection of Mycoplasma pneumoniae in hospitalized children with pneumonia in Laos by Vilivong, K, Mayxay, M, Dance, DAB, De Lamballerie, X, Newton, PN, Dubot-Pérès, A

“…<i>M. pneumoniae</i> was detected by FTD33 in the upper respiratory tract of three patients, two girls and one boy, 5.7 and 3.9 years old and 13.6 years old, respectively. They presented with clinical features compatible with <i>M. pneumoniae</i> infection. …”

Vitamin D in Gambian children with discordant tuberculosis (TB) infection status despite matched TB exposure: a case control study by Stockdale, L, Sambou, B, Sissoko, M, Egere, U, Sillah, AK, Kampmann, B, Basu Roy, R

“…Median ages of groups (infected; 10.0 years, uninfected 8.8 years) were not significantly different (p = 0.13). …”

Diagnostic performance of GENEDIA W and ActiveXpress+ COVID-19 antigens tests among symptomatic individuals in Peru and The United Kingdom by Palomino-Padilla, S, Finch, L, de Vos, M, Savage, H, Villa-Castillo, L, Hayward, G, Cook, E, LSTM diagnostics group, UTB-IMTAvH group, CONDOR steering group, Escadafal, C, Body, R, Adams, ER, Ugarte-Gil, C, Cubas-Atienzar, AI

“…Analytical evaluation of both Ag-RDTs was assessed using serial dilutions of direct culture supernatant of a clinical SARS-CoV-2 isolate from the B.1.1.7 lineage.</p> <p><strong>Results: </strong>For GENEDIA brand, the values of overall sensitivity and specificity were 60.4% [95% CI 52.4–67.9%], and 99.2% [95% CI 97.6–99.7%] respectively; and for Active Xpress+ the overall values of sensitivity and specificity were 66.2% [95% CI 54.0–76.5%], and 99.6% [95% CI 97.9–99.9%] respectively. …”