The Pandemic EVIDENCE Collaboration Pillar 1: diagnostics and transmission by Conly, J, Plüddemann, A, Jefferson, T, Rosca, C, Heneghan, C

“…The evidence produced to support the optimal deployment of NPIs to reduce transmission of SARS-CoV-2 was often of poor quality, and decisions were made without considering the wealth of previous research on respiratory virus transmission from human challenge studies. …”

The Pandemic EVIDENCE Collaboration Pillar 2: interventions and evidence by Fretheim, A, Onakpoya, I, Bartoszko, J, Jones, M, Gandini, S

“…The use of non-pharmacological interventions (NPIs) on a global scale to reduce the transmission of SARS-CoV-2 was unprecedented. However, there was a lack of high-quality evidence to fully understand the benefits and harms of these interventions. …”

From Sample to Answer: Innovations in sample processing and CRISPR-based diagnostics for enhanced clinical translation and field deployment by Arizti Sanz, Jon

“…However, the global diagnostic testing capacity is currently insufficient to effectively respond to emerging infectious disease threats, which has fueled the spread of Lassa, Ebola, SARS-CoV-2, and Zika virus in recent years. Globally, this diagnostic gap is particularly pronounced at the primary care or community level, an essential site for swift and effective response. …”
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Design language in packaging. by Wijaya, Merwyn.

“…Craid is a fictitious brand of Irish beer that is designed based on this essential role. …”
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Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Chapter 5 discusses the establishment of a medium-throughput drug screening platform against SARS-CoV-2. FDA-approved compounds were prioritised and triaged within the screen for clinical committees such as the UK steering group for therapeutics for COVID-19. …”

Strategies to increase response rate and reduce non-response bias in population health research: a series of randomised controlled trials during a large COVID-19 study by Atchison, CJ, Gilby, N, Pantelidou, G, Clemens, S, Pickering, K, Chadeau-Hyam, M, Ashby, D, Barclay, WS, Cooke, G, Darzi, A, Riley, S, Donnelly, C, Ward, H, Elliott, P

“…</p> <br> <p><strong>Methods:</strong> Over 19 rounds, a random sample of individuals aged 5 years and older from the general population in England were invited by mail to complete an online questionnaire and return a swab for SARS-CoV-2 testing. …”

Spooky action in the film/novel debate. by Lee, Tracy Marie Shiyin., Luo, Esmonde Jianwen., Wong, Kai Wing., Manoj Prabhoda Chandran., Chee, Kang Xiong.

“…The installation follows a Collector, Photographer, Writer and a Collective (a beer garden group that gathers at the local coffeeshop) in their daily life as they contemplate the curious events, and each other, in an attempt to cope with the boredom they face in the neighbourhood. …”
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Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics by Roney, Miah, Huq, AKM Moyeenul, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…COVID-19, a viral infection caused by the coronavirus SARS-CoV-2, is one of the world's most challenging diseases to cure. …”
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Synthesis and development of novel small molecule inhibitors of nucleophilic hydrolases by Gayatri

“…The work focused on the synthesis and structure activity relationship (SAR) exploration of two small molecule templates, i.e. …”

A study of Singapore pandemic by Muhammad Hafiz Abdul Rahim

“…(Transport and housing editor, 2016) Studies have shown that the number of incoming tourist and aeronautics-job related will greatly increase in 20 years’ time (Transport and housing editor, 2016). …”
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Practical and analytical considerations when performing interim analyses in diagnostic test accuracy studies by Fleming, S, Mwandigha, L, Fanshawe, T

“…The method is illustrated using two simulated data sets and data from a published diagnostic accuracy study for point-of-care testing for SARS-CoV-2. The considerations described in this paper can be used to guide decisions as to when an interim analysis in a diagnostic accuracy study is suitable and highlight areas for further methodological development.…”

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-... by Schumacher, AE, Kyu, HH, Aali, A, Almidani, O, Bandyopadhyay, S, Basnyat, B, Maude, RJ, Bennett, D, Browne, AJ, Dolecek, C, Dunachie, SJ, Newton, CRJ, Rodriguez, JAB

“…Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). …”

Optimising the surveillance and control of communicable diseases: the effects of population heterogeneity on early outbreak transmission dynamics by Lovell-Read, F

“…Then, we extend our model to account for age-dependent factors that affect SARS-CoV-2 transmission, including patterns of social contacts, variation in susceptibility to infection, and the likelihood of developing clinical symptoms. …”

The neurological consequences of contracting COVID-19 by Aknin, LB, De Neve, JE, Dunn, EW, Fancourt, DE, Goldberg, E, Helliwell, JF, Jones, SP, Karam, E, Layard, R, Lyubomirsky, S, Rzepa, A, Saxena, S, Thornton, EM, VanderWeele, TJ, Whillans, AV, Zaki, J, Caman, O, Amor, YB

“…Since the first confirmed case in Wuhan, China on December 31, 2019, the novel coronavirus (SARS-CoV-2) has spread quickly, infecting 165 million people as of May 2021. …”

Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England by Copland, E, Patone, M, Saatci, D, Handunnetthi, L, Hirst, J, Hunt, DPJ, Mills, NL, Moss, P, Sheikh, A, Coupland, CAC, Harnden, A, Robertson, C, Hippisley-Cox, J

“…In 12-17-year-olds, we estimated 3 (95%CI 0–5) and 5 (95%CI 3–6) additional cases of myocarditis per million following a first and second dose with BNT162b2, respectively. …”

An emerging network for COVID-19 CT-scan classification using an ensemble deep transfer learning model by Yousefpanah, Kolsoum, Ebadi, M. J., Sabzekar, Sina, Zakaria, Nor Hidayati, Osman, Nurul Aida, Ali Ahmadian, Ali Ahmadian

“…Over the past few years, the widespread outbreak of COVID-19 has caused the death of millions of people worldwide. …”

First nosocomial cluster of COVID-19 due to the Delta variant in a major acute care hospital in Singapore: investigations and outbreak response by Lim, Wei Yen, Tan, Glorijoy Shi En, Htun, Htet Lin, Phua, Hwee Pin, Kyaw, Win Mar, Guo, Huiling, Cui, Lin, Mak, Tze Minn, Poh, Bee Fong, Wong, Judith Chui Ching, Setoh, Yin Xiang, Ang, Brenda Sze Peng, Chow, Angela Li Ping

“…Ward air exhaust filters were tested for SARS-CoV-2. Results: In total, there were 47 cases, comprising 29 patients, nine staff, six visitors and three household contacts. …”
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Modelling the impact of testing, contact tracing and household quarantine on second waves of COVID-19 by Aleta, Alberto, Martín-Corral, David, Pastore y Piontti, Ana, Ajelli, Marco, Litvinova, Maria, Chinazzi, Matteo, Dean, Natalie E., Halloran, M. Elizabeth, Longini Jr, Ira M., Merler, Stefano, Pentland, Alex, Vespignani, Alessandro, Moro, Esteban, Moreno, Yamir

“…Here we integrate anonymized, geolocalized mobility data with census and demographic data to build a detailed agent-based model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in the Boston metropolitan area. …”
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Transfer learning-based approach for detecting COVID-19 ailment in lung CT scan by Arora, Vinay, Ng, Eddie Yin Kwee, Leekha, Rohan Singh, Darshan, Medhavi, Singh, Arshdeep

“…On the dataset Covid-CT Scan and SARS-COV-2 CT-Scan, the MobileNet model provided a precision of 94.12% and 100% respectively.…”
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Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics by Perochon, T, Krsnik, Z, Massimo, M, Ruchiy, Y, Romero, AL, Mohammadi, E, Li, X, Long, KR, Parkkinen, L, Blomgren, K, Lagache, T, Menassa, DA, Holcman, D

“…Additionally, we uncover an association between microglia and blood vessels in fetal brains exposed to maternal SARS-CoV-2. These findings offer insights into whether various microglial phenotypes form networks in the developing brain to occupy space, and in conditions involving haemorrhages, whether microglia respond to, or influence changes in blood vessel integrity. …”