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61
Interaction of TiO2 and ZnO NPs with human skin cells
Published 2019“…Therefore, the goal of this study is to assess the physiological effects of TiO2 and ZnO NPs interactions with primary human epidermal keratinocytes and dermal fibroblasts, with attention to accurate dosimetry measurements and particle solubility considerations. Since the current findings on NPs interaction with skin cells are mostly based on 2D monolayer cell culture and animal models, in this study, 3D human skin explants have also been used to better understand the effects of NPs in the skin tissue. …”
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Thesis -
62
Anchoring charge selective self-assembled monolayers for tin-lead perovskite solar cells
Published 2024“…Self-assembled monolayers (SAMs) have displayed great potential for improving efficiency and stability in p-i-n perovskite solar cells (PSCs). The anchoring of SAMs at the conductiv metal oxide substrates and their interaction with perovskite materials must be rationally tailored to ensure efficient charge carrier extraction and improved quality of the perovskite films. …”
Journal article -
63
Modeling the Impact of Electrolyte Flow on Heat Management in a Li-Ion Convection Cell
Published 2024“…We show, through physics-based electrothermal modeling and dimensional analysis of a single, planar LIB cell, that electrolyte convection can simultaneously draw heat from the cell and suppress heat generation from entropy change, charge-transfer, and ohmic losses, and that the cell temperature rise can be effectively mitigated when heat removal matches or exceeds heat generation. …”
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64
Non-targeted metabolomics revealing the effects of bisphenol analogues on human liver cancer cells
Published 2022“…Overall, BPs altered metabolites which are associated with energy metabolism, oxidative stress, cell proliferation and nucleotides synthesis. The primary dysregulated pathways included energy and nucleotides synthesis related Purine and Glycolysis/Gluconeogenesis metabolism. …”
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Journal Article -
65
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis
Published 2024“…In addition, we find an expansion of YeiH-specific CD8 T cells in the blood of axSpA and B27AAU over healthy controls, whereas influenza-specific CD8 T cells were equivalent across groups. …”
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66
Understanding the disease mechanisms of cerebellar ataxia through induced pluripotent stem cell models
Published 2018“…Finally, to determine the developmental changes in Purkinje cells, human Purkinje cells were generated from control and SCA14 iPSCs using a novel simplified protocol. …”
Thesis -
67
Techniques for analysis and integration of histology data and agent-based modelling of T cell-tumour interactions
Published 2023“…<p>Cytotoxic (CD8+) T cells form an important part of the adaptive immune response. …”
Thesis -
68
Conformational antibody binding to a native, cell-free expressed GPCR in block copolymer membranes
Published 2014“…Their biophysical characterization is, however, highly challenging because of their innate instability outside a stabilizing membrane and the difficulty of finding a suitable expression system. We here show the cell-free expression of a GPCR, CXCR4, and its direct embedding in diblock copolymer membranes. …”
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Journal Article -
69
Evaluating the ecotoxicity of agropesticides and environmental water contaminants using cell-line and zebrafish embryonic assays
Published 2023“…The results showed that the pesticides tested exhibited acute lethality and sublethal effects on the model organisms tested, albeit some to a lesser extent than previously reported findings on single active compounds. Our findings also revealed challenges in using a single broad-spectrum solid-phase extraction method to retain pesticide analytes due to their chemical complexity. …”
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Final Year Project (FYP) -
70
Analysis of hepatocyte antigen presentation and T cell/hepatocyte interaction in the context of hepatitis B virus Infection.
Published 2010“…This study aimed to analyze strategies employed by HBV to evade host’s cellular immune response, which requires an interaction of T cell receptor (TCR) and major histocompatibility complex class I (MHC I)/peptide complex for T cell activation. …”
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Final Year Project (FYP) -
71
Critical analysis of the role of biodegradable polymeric scaffolds in differentiation of human embryonic stem cell into cardiomyocytes
Published 2010“…Owing to the shortage of donors there has been a constant quest to find alternatives to organ transplant. Cell replacement therapy is a promising approach for the treatment of cardiac diseases, but is challenged by a limited supply of appropriate cells. …”
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Thesis -
72
A cross-scale framework for evaluating flexibility values of battery and fuel cell electric vehicles
Published 2024“…This article analyzed and compared the flexibility values of battery electric vehicles and fuel cell electric vehicles for planning and operating interdependent electricity and hydrogen supply chains while considering battery degradation costs. …”
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73
Preparation and characterization of photo electrochemical cells based on nanostructured ZnO and multiwalled carbon nanotubes
Published 2010“…The synthesis of the PEC cell with glass/FtO as base is done using Chemical Bath Deposition Technique. …”
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Final Year Project (FYP) -
74
Characterization of progesterone receptor isoform-selective activities of progesterone receptor modulators in breast cancer cells.
Published 2008“…This study reveals the effects of progesterone receptor modulators (PRMs) mediated by PR isoforms in PR-transfected MDA-MB-231 cells. Through PR-A and PR-B, PRMs CP8668, AED and Dex-Mes exhibited progesterone agonist effect in which they induced cell spreading, focal adhesion, cell migration and inhibited cell cycle progression. …”
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Thesis -
75
B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination
Published 2022“…B cells are important in immunity to both severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and vaccination, but B cell receptor (BCR) repertoire development in these contexts has not been compared. …”
Journal article -
76
Elucidating the size-dependency of in vitro digested polystyrene microplastics on human intestinal cells health and function
Published 2022“…Interestingly, it is found that the 0.1 µm PS-MPs can perturb redox homeostasis in NCM460 but not in Caco-2 cells. Based on the in vitro experimental boundaries and findings, it is concluded that ingested PS-MPs pose little acute cytotoxic harm to human gastrointestinal health.…”
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Journal Article -
77
Sygyzium claviflorum fruit extract preadipocyte differentiation inhibition in 3T3-L1 cells
Published 2024“…Similarly, this study aimed to establish Sygyzium claviflorum fruit extract (SCFE) anti-adipogenic attributes in 3T3-L1 cells. Methods: The polyphenolic compounds in SCFE were identified with Reverse phase-high performance liquid chromatography (RP-HPLC). …”
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78
The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy
Published 2017“…We therefore sought to find a conclusive answer to the question of whether Aβ affects cell plasma membrane fluidity. …”
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Thesis -
79
Cathodoluminescence of self-organized heterogeneous phases in multidimensional perovskite thin films
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Journal Article -
80
A novel method for segmenting growth of cells in sheared endothelial culture reveals the secretion of an anti-inflammatory mediator
Published 2018“…In one paradigm, endothelial cells are cultured in devices that produce spatially varying shear stress profiles, and the local profile is compared with the properties of cells at the same position. …”
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Journal Article