Vypal2: a versatile peptide ligase for precision tailoring of proteins by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa

“…The last two decades have seen an increasing demand for new protein-modification methods from the biotech industry and biomedical research communities. Owing to their mild aqueous reaction conditions, enzymatic methods based on the use of peptide ligases are particularly desirable. …”
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Experimental Characterization of Iron-Sulfur Cluster Excited States and their Relevance to Electron Transfer Reactions by Skeel, Brighton A.

“…We find additionally that the primary coordination sphere has a strong influence on the topography of these excited state landscapes, in particular that the donor properties of the ligands binding an [Fe₄S₄]¹⁺ cluster determine its ground state valence electron distribution. …”
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Methyl and dimethyl o-xylenyl-substituted fullerene acceptors for polymer solar cells by Kim, Hee Un, Park, Jong Baek, Grimsdale, Andrew Clive, Hwang, Do-Hoon

“…These values correlate with the binding affinities of the fluorophore and quencher. …”
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Use of peptide asparginyl ligases (PALs) in generating alternative non-Ig protein-drug conjugates for cancer therapy by See, Julia Jing Yi

“…Due to challenges regarding limited time constraints and unforeseen power outage, future investigation to assess Affibody & DARPin binding affinity (Kd) and half-maximal inhibitory concentration (IC50) to unravel further insights into non-Ig proteins with enzymatic ligation for therapeutic applications.…”
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Structure of the C-terminal domain of the multifunctional ICP27 protein from herpes simplex virus 1 by Nordlund, Par, Patel, Vidhi, Dahlroth, Sue-Li, Rajakannan, Venkatachalam, Ho, Hai Ting, Cornvik, Tobias

“…The structure reveals the C-terminal half of ICP27 to have a novel fold consisting of -helices and long loops, along with a unique CHCC-type of zinc-binding motif. …”
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A study of human monoclonal antibodies to influenza and ebola viruses by Rijal, P

“…Despite these features, half of the antibodies neutralised an Ebola surrogate virus <em>in vitro</em>, and many were therapeutic in a murine infection model. …”

Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum by Song, Yutong, Zhao, Zhihao, Xu, Linyu, Huang, Peiyuan, Gao, Jiayang, Li, Jingxuan, Wang, Xuejie, Zhou, Yiren, Wang, Jinhui, Zhao, Wenting, Wang, Likun, Zheng, Chaogu, Gao, Bo, Jiang, Liwen, Liu, Kai, Guo, Yusong, Yao, Xiaoqiang, Duan, Liting

“…Sustained mechanostimuli increase the levels of binding-immunoglobulin protein (BiP) expression and phosphorylated eIF2α, two markers for ER stress. …”
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Label-free microfluidic cell sorting and detection for rapid blood analysis by Lu, Nan, Tay, Hui Min, Petchakup, Chayakorn, He, Linwei, Gong, Lingyan, Maw, Kay Khine, Leong, Sheng Yuan, Lok, Wan Wei, Ong, Hong Boon, Guo, Ruya, Li, Holden King Ho, Hou, Han Wei

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Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell] by He, Zuxing

“…Synsepalum dulcificum, is a kind of berries, when eaten causes sour foods subsequently consumed to taste sweet. …”
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π-fused diazocines with controllable photoswitching properties as molecular tweezers by Yuan, Wei, Wu, Mengjiao, Qian, Cheng, Guo, Jingjing, Wu, Yinglong, He, Ting, Wei, Haipeng, Chen, Xiaokai, Wang, Dongdong, Liu, Jiawei, Zhao, Yue, Wang, Shihuai, Yang, Jie, Zhang, Zhongzheng, Chen, Yulan, Zhao, Yanli

“…This work may pave the way for designing novel photoswitches with long half-lives and lightcontrolled properties.…”
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Surface plasmon resonance (SPR) enhanced biosensors by Zhang, Jinling

“…A biosensor is a device that employs biomolecules or biomimetic components as capturing elements to detect analyte, record the information, which is translated mostly into electric signals. Different kinds of biosensors are based on different detection principles. …”
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Crack healing in reactive MgO-slag system via bacteria induced carbonate precipitation by Zheng, Yanying

“…In the Concrete industry, the most widely used binding ingredient for concrete, portland cement (PC), is accountable for around 8% of global anthropogenic carbon dioxide (CO2) emissions. …”
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Nonreciprocal phenomena in superconductivity by Davydova, Marharyta

“…Nonreciprocal superconductors describe certain classes of unconventional superconductors that include certain kinds of mixed-pairing and finite-momentum ones. …”
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Conformational changes involved in signal transduction in avian cryptochromes by Gehrckens, AS

“…</p> <p>Finally, by mapping conformational changes found in molecular dynamics simulations onto changes observed in a previous HDX-MS data set on the <em>Drosophila</em> cryptochrome, a few gaps left by the incomplete coverage of the current experimental data were filled by acquiring information on the phosphate-binding loop and the protrusion motif, two regions which have also been found to undergo light-induced structural changes for the avian cryptochromes investigated. …”

Three-component Friedel-Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(iii) electrophile by Kikuchi, Jun, Nagata, Toya, Ito, Shingo, Yoshikai, Naohiko

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Investigation of fluorescence lifetime imaging for quantitative cervical cancer screening and diagnosis by Gu, Jun

“…In addition, analyzing only the top-half of the cervical epithelium shortens the calculation time. …”
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Fabrication and characterization of hybrid perovskite thin films for solar cell application by Dayal, Akhilesh

“…Over the decades, various kinds of research and experimentations have been done to increase the efficiency of the solar cell. …”
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Restoring product focus across the value stream through organizational restructuring by Pasqual, Jeffrey M. (Jeffrey Michael)

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Theoretical Modelling and Facile Synthesis of a Highly Active Boron-Doped Palladium Catalyst for the Oxygen Reduction Reaction by Vo Doan, Tat Thang, Wang, Jingbo, Poon, Kee Chun, Tan, Desmond Chun Long, Khezri, Bahareh, Webster, Richard David, Su, Haibin, Sato, Hirotaka

“…Our theoretical modelling reveals that B-doped Pd (Pd-B) weakens the absorption of ORR intermediates with nearly optimal binding energy by lowering the barrier associated with O2 dissociation, suggesting Pd-B should be highly active for ORR. …”
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清末女性解放运动的厌女症研究 = Feminism in China : an analysis of misogyny in the feminism movement in late Qing dynasty by 朱彤萱 Cho, Tong Xuan

“…Following the defeat of China in the Sino-Japanese War, reform-minded Chinese intellectuals showed their concerns on the women’s liberation as the women are the cause to the failure of the country. …”
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