Biotin-streptavidin binding interactions of dielectric filled silicon bulk acoustic resonators for smart label-free biochemical sensor applications by Heidari, Amir, Yoon, Yong-Jin, Park, Woo-Tae, Su, Pei-Chen, Miao, Jianmin, Park, Mi Kyoung, Lin, Julius Tsai Ming

“…Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. …”
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The ties that bind: on affective ties, power, nationalism, and competition over the global distribution of feeling by Hall, T, James, P

Unveiling the chirality of the quantum anomalous Hall effect by Chen, Hongyu, Jin, Yuanjun, Mohammad Yahyavi, Belopolski, Ilya, Shao, Sen, Hou, Tao, Wang, Naizhou, Hsu, Chia-Hsiu, Zhao, Yilin, Yang, Bo, Ma, Qiong, Yin, Jia-Xin, Xu, Su-Yang, Gao, Weibo, Chang, Guoqing

“…The ordinary and quantum Hall effects with fixed carrier types, electron or hole, exhibit well-defined chirality under external magnetic fields, but the analogous chirality of the quantum anomalous Hall effect (QAHE) remains little explored. …”
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Biocementation of sand filled geotextile tubes by Yong, Hoi Zett

“…Nonetheless, the strength and durability of geotextile tubes that filled with sand or clay slurry still need to be improved. …”
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Skyrmion-driven topological Hall effect in a Shastry-Sutherland magnet by Swain, N., Shahzad, M., Paradezhenko, G. V., Pervishko, A. A., Yudin, D., Sengupta, Pinaki

“…By constructing an effective tight-binding model of conduction electrons coupled to the skyrmion lattice, we clearly demonstrate the appearance of the topological Hall effect. …”
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Structural and functional characterisation of the collagen binding domain of fibronectin by Millard, CJ

“…However, the presence of at least a single GlcNAc sugar residue on the second sugar chain site on 8Fn1 (N- linked to N511) is essential for full affinity binding to collagen. Direct binding of the 8Fn1-9Fn1 module pair to collagen is assessed with a short collagen peptide and the binding is monitored by NMR. …”

Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics by Lukman, Suryani., Lane, David P., Verma, Chandra S.

“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…In silico analysis using RosettaLigand and GLIDE demonstrated a well-converged pose of SKA-346 in a binding pocket at the interface between the calmodulin N-lobe and the S45A helix in the S4-S5 linker of the KCa3.1 channel. …”
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Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore by Ivan, Fransiskus Xaverius, Zhou, Xinrui, Lau, Suk Hiang, Rashid, Shamima, Teo, Jasmine S. M., Lee, Hong Kai, Koay, Evelyn S., Chan, Kwai Peng, Leo, Yee Sin, Chen, Mark I. Cheng, Kwoh, Chee Keong, Chow, Vincent T.

“…Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificity. …”
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Induction of z-conformation in ribosomal RNA by Z-DNA binding domain Zα of the human double-stranded RNA deaminase I (ADAR1) by Zhao, Jing

“…Therefore, our theoretical model shall predict whether the chemical shifts perturbations observed through the small binding partner can be used to delineate the involved binding interface, and whether changes of the positions of NMR resonances or only attenuation of the cross-peak intensities are to be expected upon binding to a solid partner.…”
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Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro,... by Yang, Z, Sheehan, AM, Messer, AE, Tsui, S, Sparrow, A, Redwood, C, Kren, V, Gould, IR, Marston, SB

“…Results: Silybin B, EGCG and resveratrol restored the phosphorylation-induced change in molecular dynamics to wild-type values, whilst silybin A, an inactive isomer of silybin B, and Epicatechin gallate, an EGCG analogue that does not recouple, did not. …”

Myopathy-causing Q147P TPM2 mutation shifts tropomyosin strands further towards the open position and increases the proportion of strong-binding cross-bridges during the ATPase cyc... by Karpicheva, OE, Simonyan, AO, Kuleva, NV, Redwood, CS, Borovikov, YS

“…Despite its reduced affinity for actin in co-sedimentation assay, the Q147P mutant incorporates into the muscle fiber. However, compared to wild-type tropomyosin, it locates closer to the center of the actin filament. …”

Structural features that affect β2 integrin expression and regulation of adhesion by Guan, Siyu

“…(It should be noted that wild-type LFA-1 requires one activating agent to bind ICAM-1 and two to bind ICAM-3.) …”
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The role of growth factor receptor bound protein 2 (GRB2) in gain of function of mutant p53. by Lau, Sok Ting.

“…In this study, GRB2, a binding partner of mutant p53 was explored to uncover its role in mutant p53 “gain-of-function”. …”
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Computational investigations of HIV-1 protease and protease inhibitors interactions by Sham, Hoi Fung

“…Both wild type HIV-1 proteases and mutated HIV-1 proteases were used in the docking simulations. …”
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Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…</p> <br> <p>The findings of ‘STORY’ confirm that SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalisation. …”

Recognition of A-U and U-A base pairs in RNA duplexes by modified peptide nucleic acids by Yuan, Zhen

“…Fluorescence binding studies were carried out to measure the binding affinity at physiological pH conditions. …”
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Structural basis of haptoglobin-haemoglobin scavenging by CD163 by Zhou, X

“…Indeed, biophysical assays show that calcium ions are critical for ligand binding. Mutational studies demonstrate that while monomeric CD163 can scavenge the multimeric Hp(2-2)Hb, uptake of the dimeric Hp(1-1)Hb and Hb is impaired compared to the wild-type receptor, suggesting that receptor multimerisation evolved to facilitate uptake of lower affinity ligands. …”

Thermal induced coupling of cell adhesion/deadhesion and migration under HBV replication and EGCG treatment by Li, Xi

“…In the first part of my thesis, TRP was applied as a model system for elucidating the effect of HBV replication on the biophysical responses of HepG2 cells transfected by wild type HBV genome. Moreover, mutant HBV genome is designed to assess the specific activity of the SH3-binding domain of HBx during HBV replication. …”
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Effect of post-deposition annealing on the interface electronic structures of Al2O3-Capped GaN and GaN/AlGaN/GaN heterostructure by Duan, Tian Li, Pan, Ji Sheng, Ang, Diing Shenp

“…The interface electronic structures of GaN and GaN/AlGaN/GaN samples, capped with atomic-layer-deposited Al2O3 and subjected to varying post-deposition annealing (PDA) temperatures, are investigated by X-ray photoelectron spectroscopy (XPS) and Hall-effect measurement. XPS study shows a decrease in the Ga 3d and N 1s core level binding energy after a high-temperature PDA, implying a decrease of the interface defect density and the associated positive trapped-charge. …”
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